Circadian variation in BDNF mRNA expression in the rat hippocampus

Publication Type:

Journal Article

Source:

Brain Res Mol Brain Res, Volume 75, Number 2, p.342-344 (2000)

ISBN:

0169-328X (Print)0169-32

DOI Name (links to online publication)

10.1016/S0169-328X(99)00314-9

Keywords:

Animals; Brain-Derived Neurotrophic Factor/biosynthesis/*genetics; Circadian Rhythm/*genetics; Corticosterone/physiology; Gene Expression Regulation; Hippocampus/*metabolism; In Situ Hybridization; Male; RNA; Messenger/biosynthesis; Rats; Rats; Wistar

Abstract:

BDNF mRNA levels in the hippocampus were studied during the circadian cycle by in situ hybridization. These levels display a circadian pattern, which may be due to regulation by corticosterone. This may have consequences for hippocampal functioning at different time points of the circadian cycle.

18/01/2013