All journal publications (1904-2014)

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2014
Daskalakis, N.P., Diamantopoulou, A., Claessens, S.E., Remmers, E., Tjalve, M., Oitzl, M.S., Champagne, D.L., de Kloet, E.R. , Early experience of a novel-environment in isolation primes a fearful phenotype characterized by persistent amygdala activation, Psychoneuroendocrinology, vol. 39, pp. 39-57. DOI
2013
Diamantopoulou, A., Raftogianni, A., Stamatakis, A., Oitzl, M.S., Stylianopoulou, F. , Effects of denial of reward through maternal contact in the neonatal period on adult hypothalamic-pituitary-adrenal axis function in the rat, Psychoneuroendocrinology, vol. 38, issue 6, pp. 830-841. DOI
Albrecht, A., Caliskan, G., Oitzl, M.S., Heinemann, U., Stork, O. , Long-Lasting Increase of Corticosterone After Fear Memory Reactivation: Anxiolytic Effects and Network Activity Modulation in the Ventral Hippocampus, Neuropsychopharmacology, vol. 38, pp. 386–394. DOI
Harris, A.P., Holmes, M.C., de Kloet, E.R., Chapman, K.E., Seckl, J.R. , Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour, Psychoneuroendocrinology, vol. 38, no. 5, pp. 648-658. DOI
Schumann, G., Binder, E.B., Holte, A., de Kloet, E.R., Oedegaard, K.J., Robbins, T.W., Walker-Tilley, T.R., Bitter, I, Brown, V.J., Buitelaar, J., Ciccocioppo, R., Cools, R., Escera, C., Fleischhacker, W., Flor, H., Frith, C.D., Heinz, A., Johnsen, E., Kirschbaum, C., Klingberg, T., Lesch, K.P., Lewis, S., Maier, W., Mann, K., Martinot, J.L., Meyer-Lindenberg, A., Muller, C.P., Muller, W.E., Nutt, D.J., Persico, A., Perugi, G., Pessiglione, M., Preuss, U.W., Roiser, J.P., Rossini, P.M., Ryba, , Stratified medicine for mental disorders, Eur Neuropsychopharmacol. DOI
Zalachoras, I, Houtman, R., Atucha, E., Devos, R., Tijssen, A.M., Hu, P., Lockey, P.M., Datson, N.A., Belanoff, J.K., Lucassen, P.J., Joels, M., de Kloet, E.R., Roozendaal, B., Hunt, H., Meijer, O.C. , Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator, PNAS, vol. 110, no. 19, pp. 7910-7015. DOI
Evers, M.M., Tran, H.D., Zalachoras, I, Pepers, B.A., Meijer, O.C., den Dunnen, J.T., van Ommen, G.J., Aartsma-Rus, A., van Roon-Mom, W.M. , Ataxin-3 protein modification as a treatment strategy for Spinocerebellar Ataxia type 3: Removal of the CAG containing exon, Neurobiology of disease. DOI
Aubert, Y., Bohl, M.A., Lange, J.R., Diol, N.R., Allers, K.A., Sommer, B., Datson, N.A., Abbott, D.H. , Chronic systemic administration of serotonergic ligands flibanserin and 8-OH-DPAT enhance HPA axis responses to restraint in female marmosets, Psychoneuroendocrinology, vol. 38, no. 1, pp. 145-154. DOI
Zalachoras, I, Houtman, R., Meijer, O.C. , Understanding stress-effects in the brain via transcriptional signal transduction pathways, Neuroscience, vol. 242, pp. 97-109. DOI
Daskalakis, N.P., Bagot, R.C., Parker, K.J., Vinkers, C.H., de Kloet, E.R. , The three-hit concept of vulnerability and resilience: Toward understanding adaptation to early-life adversity outcome, Psychoneuroendocrinology. DOI
Zalachoras, I, Grootaers, G., van Weert, L.T., Aubert, Y., de Kreij, S.R., Datson, N.A., van Roon-Mom, W.M., Aartsma-Rus, A., Meijer, O.C. , Antisense-mediated isoform switching of steroid receptor coactivator-1 in the central nucleus of the amygdala of the mouse brain, BMC neuroscience, vol. 14, no. 1, pp. 5. DOI
Vreeburg, S.A., Hoogendijk, W.J., de Rijk, R.H., van Dyck, R., Smit, J.H., Zitman, F.G., Penninx, B.W. , Salivary cortisol levels and the 2-year course of depressive and anxiety disorders, Psychoneuroendocrinology. DOI
Eising, E., Datson, N.A., van den Maagdenberg, A.M., Ferrari, M.D. , Epigenetic mechanisms in migraine: a promising avenue?, BMC medicine, vol. 11, no. 1, pp. 26. DOI
Ter Horst, J.P., Kentrop, J., de Kloet, E.R., Oitzl, M.S. , Stress and estrous cycle affect strategy but not performance of female C57BL/6J mice, Behavioural Brain Research, vol. 241, pp. 92-95. DOI
Fitzsimons, C.P., van Hooijdonk, L.W., Schouten, M., Zalachoras, I, Brinks, V., Zheng, T., Schouten, T.G., Saaltink, D.J., Dijkmans, T., Steindler, D.A., Verhaagen, J., Verbeek, F.J., Lucassen, P.J., de Kloet, E.R., Meijer, O.C., Karst, H., Joels, M., Oitzl, M.S., Vreugdenhil, E. , Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior, Molecular Psychiatry, vol. 18, issue 9, pp. 993-1005. DOI
Schilling, T.M., de Ferreira Sa, D.S., Westerhausen, R., Strelzyk, F., Larra, M.F., Hallschmid, M., Savaskan, E., Oitzl, M.S., Busch, H.P., Naumann, E., Schachinger, H. , Intranasal insulin increases regional cerebral blood flow in the insular cortex in men independently of cortisol manipulation, Human brain mapping. DOI
Reynolds, R.M., Hii, H.L., Pennell, C.E., McKeague, I.W., de Kloet, E.R., Lye, S., Stanley, F.J., Mattes, E., Foster, J.K. , Analysis of baseline hypothalamic-pituitary-adrenal activity in late adolescence reveals gender specific sensitivity of the stress axis, Psychoneuroendocrinology, vol. 38, no. 8, pp. 1271-1280. DOI
Kruk, M.R., Haller, J., Meelis, W., de Kloet, E.R. , Mineralocorticoid receptor blockade during a rat's first violent encounter inhibits its subsequent propensity for violence, Behavioral Neuroscience, vol. 127, no. 4, pp. 505-514. DOI
Datson, N.A., van den Oever, J.M., Korobko, O.B., Magarinos, A.M., de Kloet, E.R., McEwen, B. , Prior history of chronic stress changes the transcriptional response to glucocorticoid challenge in the dentate gyrus region of the male rat hippocampus, Endocrinology. DOI
Speksnijder, N. , Determinants of psychosis vulnerability: Focus on MEF2- and glucocorticoid signaling, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 160.
de Kloet, E.R., Joels, M. , Stress Research: Past, Present, and Future, Neuroscience in the 21st Century: Springer New York, pp. 1979-2007. DOI
de Kloet, E.R. , Resilience and Vulnerability: A Matter of Stress, Genes and Balance, Biological Psychiatry, vol. 73, no. 9, pp. 112s-112s. DOI
Ter Horst, J.P., Kentrop, J., Arp, M., Hubens, C.J., de Kloet, E.R., Oitzl, M.S. , Spatial learning of female mice: a role of the mineralocorticoid receptor during stress and the estrous cycle, Frontiers in Behavioral Neuroscience, vol. 7, pp. 56. DOI
Verissimo, C.S., Elands, R., Cheng, S., Saaltink, D.J., ter Horst, J.P., Alme, M.N., Pont, C., van de Water, B., Håvik, B., Fitzsimons, C.P., Vreugdenhil, E. , Silencing of Doublecortin-Like (DCL) Results in Decreased Mitochondrial Activity and Delayed Neuroblastoma Tumor Growth, PLoS One, vol. 8, no. 9: Public Library of Science, pp. e75752. DOI
2012
Joels, M., de Kloet, E.R. , Nothing is written in stone, Biological Psychiatry, vol. 72, no. 6, pp. 432-433. DOI
Verissimo, C.S., Molenaar, J.J., Meerman, J.H., Puigvert, J.C., Pont, C., Danen, E.H.J., van de Water, B., Versteeg, R., Fitzsimons, C.P., Vreugdenhil, E. , Doublecortin-Like Kinase: A Potential Therapeutic Target for Neuroblastoma, Neuro-Oncology, vol. 14, no. Suppl. 3, pp. 91-91. DOI
Polman, J.A., Hunter, R.G., Speksnijder, N., van den Oever, J.M., Korobko, O.B., McEwen, B.S., de Kloet, E.R., Datson, N.A. , Glucocorticoids Modulate the mTOR Pathway in the Hippocampus: Differential Effects Depending on Stress History, Endocrinology, vol. 153, no. 9, pp. 4317-4327. DOI
Claessens, S.E., Belanoff, J.K., Kanatsou, S., Lucassen, P.J., Champagne, D.L., de Ronald Kloet, E. , Acute effects of neonatal dexamethasone treatment on proliferation and astrocyte immunoreactivity in hippocampus and corpus callosum: towards a rescue strategy, Brain Research, vol. 1482, pp. 1-12. DOI
Polman, J.A., Welten, J.E., Bosch, D.S., de Jonge, R.T., Balog, J., van der Maarel, S.M., de Kloet, E.R., Datson, N.A. , A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells, BMC neurosci, vol. 13, no. 1, pp. 118. DOI
Hunter, R.G., Murakami, G., Dewell, S., Seligsohn, M., Baker, M.E., Datson, N.A., McEwen, B.S., Pfaff, D.W. , Acute stress and hippocampal histone H3 lysine 9 trimethylation, a retrotransposon silencing response, Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 43, pp. 17657-17662. DOI
de Vrij, J., Dautzenberg, I.J., van den Hengel, S.K., Magnusson, M.K., Uil, T.G., Cramer, S.J., Vellinga, J., Verissimo, C.S., Lindholm, L., Koppers-Lalic, D., Hoeben, R.C. , A cathepsin-cleavage site between the adenovirus capsid protein IX and a tumor-targeting ligand improves targeted transduction, Gene Ther, vol. 19, no. 9, pp. 899-906. DOI
Ter Horst, J.P., de Kloet, E.R., Schachinger, H., Oitzl, M.S. , Relevance of Stress and Female Sex Hormones for Emotion and Cognition, Cell Mol Neurobiol, vol. 32, no. 5, pp. 725-735. DOI
Witzmann, S.R., Turner, J.D., Meriaux, S.B., Meijer, O.C., Muller, C.P. , Epigenetic regulation of the glucocorticoid receptor promoter 1 7 in adult rats, Epigenetics, vol. 7, no. 11, pp. 1290-1301. DOI
Speksnijder, N., Christensen, K.V., Didriksen, M., De Kloet, E.R., Datson, N.A. , Glucocorticoid Receptor and Myocyte Enhancer Factor 2 Cooperate to Regulate the Expression of c-JUN in a Neuronal Context, J Mol Neurosci, vol. 48, no. 1, pp. 209-218. DOI
Saaltink, D.J., Håvik, B., Verissimo, C.S., Lucassen, P., Vreugdenhil, E. , Doublecortin and doublecortin-like are expressed in overlapping and non-overlapping neuronal cell population: Implications for neurogenesis, J Comp Neurol, vol. 13, pp. 2805–2823. DOI
Tolmacheva, E.A., Oitzl, M.S., van Luijtelaar, G. , Stress, glucocorticoids and absences in a genetic epilepsy model, Horm Behav, vol. 61, no. 5, pp. 706-710. DOI
Groeneweg, F.L., Karst, H., de Kloet, E.R., Joels, M. , Mineralocorticoid and glucocorticoid receptors at the neuronal membrane, regulators of nongenomic corticosteroid signalling, Mol Cell Endocrinol, vol. 350, no. 2, pp. 299-309. DOI
Oitzl, M.S., Schwabe, L., Aggleton, J.P. , Memory formation: Its changing face, Neurosci Biobehav Rev, vol. 36, no. 7, pp. 1577–1578. DOI
Schnörr, S.J., Steenbergen, P.J., Richardson, M.K., Champagne, D.L. , Measuring thigmotaxis in larval zebrafish, Behav Brain Res, vol. 228, no. 2, pp. 367-374. DOI
Converse, A.K., Aubert, Y., Farhoud, M., Weichert, J.P., Rowland, I.J., Ingrisano, N.M., Allers, K.A., Sommer, B., Abbott, D.H. , Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets, Neuroimage, vol. 60, no. 1, pp. 447-55. DOI
Ter Horst, J.P., Carobrez, A.P., van der Mark, M.H., de Kloet, E.R., Oitzl, M.S. , Sex differences in fear memory and extinction of mice with forebrain-specific disruption of the mineralocorticoid receptor, Eur J Neurosci, vol. 36, no. 8, pp. 3096–3102. DOI
Daskalakis, N.P., Oitzl, M.S., Schachinger, H., Champagne, D.L., de Kloet, E.R. , Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity, Physiol Behav, vol. 106, no. 5, pp. 707–721. DOI
Strelzyk, F., Hermes, M., Naumann, E., Oitzl, M.S., Walter, C., Busch, H.P., Richter, S., Schachinger, H. , Tune it down to live it up? Rapid, nongenomic effects of cortisol on the human brain, J Neurosci, vol. 32, no. 2, pp. 616-625. DOI
Claessens, S.E., Daskalakis, N.P., Oitzl, M.S., de Kloet, E.R. , Neonatal Handling Rescues Later-Life Cognitive Impairment Programmed by Early-Life Glucocorticoid Treatment, Age and Ageing, vol. 41, pp. 47-47. DOI
Aubert, Y., Gustison, M.L., Gardner, L.A., Bohl, M.A., Lange, J.R., Allers, K.A., Sommer, B., Datson, N.A., Abbott, D.H. , Flibanserin and 8-OH-DPAT Implicate Serotonin in Association between Female Marmoset Monkey Sexual Behavior and Changes in Pair-Bond Quality, J Sex Med, vol. 9, no. 3, pp. 694–707. DOI
Boelen, A., van Beeren, M., Vos, X., Surovtseva, O., Belegri, E., Saaltink, D.J., Vreugdenhil, E., Kalsbeek, A., Kwakkel, J., Fliers, E. , Leptin administration restores the fasting-induced increase of hepatic type 3 deiodinase expression in mice, Thyroid, vol. 22, no. 2, pp. 192-199. DOI
Datson, N.A., Speksnijder, N., Mayer, J.L., Steenbergen, P.J., Korobko, O., Goeman, J., de Kloet, E.R., Joels, M., Lucassen, P.J. , The transcriptional response to chronic stress and glucocorticoid receptor blockade in the hippocampal dentate gyrus, Hippocampus, vol. 22, no. 2, pp. 359-371. DOI
Sarabdjitsingh, R.A., Conway-Campbell, B.L., Leggett, J.D., Waite, E.J., Meijer, O.C., de Kloet, E.R., Lightman, S.L. , Stress Responsiveness Varies over the Ultradian Glucocorticoid Cycle in a Brain-Region-Specific Manner (vol 151, pg 5369, 2010), Endocrinology, vol. 153, no. 12, pp. 6159-6159. DOI
Claessens, S.E., Daskalakis, N.P., Oitzl, M.S., de Kloet, E.R. , Early handling modulates outcome of neonatal dexamethasone exposure, Horm Behav, vol. 62, no. 4, pp. 433–441. DOI
Schwabe, L., Joels, M., Roozendaal, B., Wolf, O.T., Oitzl, M.S. , Stress effects on memory: An update and integration, Neurosci Biobehav Rev, vol. 36, no. 7, pp. 1740-1749. DOI
Verissimo, C.S., Cheng, S., Puigvert, J.C., Qin, Y., Vroon, A., van Deutekom, J., Price, L.S., Danen, E.H., van de Water, B., Fitzsimons, C.P., Vreugdenhil, E. , Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells, J Pharmacol Exp Ther, vol. 342, no. 1, pp. 119-130. DOI
Ter Horst, J.P., van der Mark, M.H., Arp, M., Berger, S., de Kloet, E.R., Oitzl, M.S. , Stress or no stress: Mineralocorticoid receptors in the forebrain regulate behavioral adaptation, Neurobiol Learn Mem, vol. 98, no. 1, pp. 33–40. DOI
Sarabdjitsingh, R.A., Joels, M., de Kloet, E.R. , Glucocorticoid pulsatility and rapid corticosteroid actions in the central stress response, Physiol Behav, vol. 106, no. 1, pp. 73-80. DOI
Claessens, S.E. , Programming the brain: Towards intervention strategies, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Dalm, S. , Towards a mouse model of depression : a psychoneuroendocrine approach, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 248.
Aubert, Y. , Sex, Aggression and Pair-Bond: A study on the serotonergic regulation of female sexual function in the Marmoset Monkey, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 191.
Verissimo, C.S.L. , Doublecortin-like kinase: a potential therapeutic target for neuroblastoma, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Joels, M., de Kloet, E.R., Karst, H. , Corticosteroid Actions on Neurotransmission, Handbook of Neuroendocrinology, San Diego, Academic Press, pp. 415-431. DOI
Diamantopoulou, A., Raftogianni, A., Stamatakis, A., Alikaridis, F., Oitzl, M.S., Stylianopoulou, F. , Denial of reward in the neonate shapes sociability and serotonergic activity in the adult rat, PLoS One, vol. 7, no. 3, pp. e33793. DOI
Deuter, C.E., Kuehl, L.K., Blumenthal, T.D., Schulz, A., Oitzl, M.S., Schachinger, H. , Effects of cold pressor stress on the human startle response, PLoS One, vol. 7, no. 11, pp. e49866. DOI
Steenbergen, P.J., Metz, J.R., Flik, G., Richardson, M.K., Champagne, D.L. , Methods to Quantify Basal and Stress-Induced Cortisol Response in Larval Zebrafish, Zebrafish Neurobehavioral Protocols, vol. 66: Humana Press, Springer, pp. 121-141. DOI
Dalm, S., de Kloet, E.R., Oitzl, M.S. , Post-training reward partially restores chronic stress induced effects in mice, PLoS One, vol. 7, no. 6, pp. e39033. DOI
de Kloet, E.R. , Stress and the Hippocampus, The Clinical Neurobiology of the Hippocampus: An integrative view , Oxford, Oxford University Press. DOI
Sarabdjitsingh, R.A., Kofink, D., Karst, H., de Kloet, E.R., Joels, M. , Stress-induced enhancement of mouse amygdalar synaptic plasticity depends on glucocorticoid and ss-adrenergic activity, PLoS One, vol. 7, no. 8, pp. e42143. DOI
Steenbergen, P.J., Richardson, M.K., Champagne, D.L. , The light-dark preference test for larval zebrafish, Zebrafish Protocols for Neurobehavioral Research, vol. 66: Humana Press, Springer, pp. 21-35. DOI
2011
Klok, M.D., Vreeburg, S.A., Penninx, B.W., Zitman, F.G., de Kloet, E.R., De Rijk, R.H. , Common functional mineralocorticoid receptor polymorphisms modulate the cortisol awakening response: Interaction with SSRIs, Psychoneuroendocrinology, vol. 36, no. 4, pp. 484-494. DOI
Steenbergen, P.J., Richardson, M.K., Champagne, D.L. , Patterns of avoidance behaviours in the light/dark preference test in young juvenile zebrafish: a pharmacological study, Behav Brain Res, vol. 222, no. 1, pp. 15-25. DOI
Strelzyk, F., Hermes, M., Naumann, E., Oitzl, M.S., Walter, C., Busch, H.P., Richter, S., Schachinger, H. , Rapid, Non-Genomic Effects of Cortisol on the Central Nervous System in Humans, Psychophysiology, vol. 48, pp. S113-S113. DOI
Verissimo, C.S., Molenaar, J.J., Fitzsimons, C.P., Vreugdenhil, E. , Neuroblastoma therapy: what's in the pipeline?, Endocr Relat Cancer, vol. 18, no. 6, pp. R213-R231. DOI
Veen, G., Giltay, E.J., van Vliet, I.M., De Rijk, R.H., Klaassens, E.R., van Pelt, J., Zitman, F.G. , C-reactive protein polymorphisms are associated with the cortisol awakening response in basal conditions in human subjects, Stress, vol. 14, no. 2, pp. 128-135. DOI
Steenbergen, P.J., Richardson, M.K., Champagne, D.L. , The use of the zebrafish model in stress research, Prog Neuropsychopharmacol Biol Psychiatry, vol. 35, no. 6, pp. 1432-1451. DOI
Datson, N.A., Polman, J.A., de Jonge, R.T., van Boheemen, P.T., van Maanen, E.M., Welten, J., McEwen, B.S., Meiland, H.C., Meijer, O.C. , Specific regulatory motifs predict glucocorticoid responsiveness of hippocampal gene expression, Endocrinology, vol. 152, no. 10, pp. 3749-3757. DOI
de Leeuw-van Weenen, J.E., Auvinen, H.E., Parlevliet, E.T., Coomans, C.P., der Schröder-van Elst, J.P., Meijer, O.C., Pijl, H. , Blocking dopamine D2 receptors by haloperidol curtails the beneficial impact of calorie restriction on the metabolic phenotype of high fat diet induced obese mice, J Neuroendocrinol, vol. 23, no. 2, pp. 158-167. DOI
van Leeuwen, N., Bellingrath, S., de Kloet, E.R., Zitman, F.G., De Rijk, R.H., Kudielka, B.M., Wust, S. , Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: Implication for the stress response, Psychoneuroendocrinology, vol. 36, no. 5, pp. 699-709. DOI
Schmidt, M.V., Wang, X.D., Meijer, O.C. , Early life stress paradigms in rodents: potential animal models of depression?, Psychopharmacology, vol. 214, no. 1, pp. 131-140. DOI
Datson, N.A., Speksnijder, N., de Jong, I.E.M., Steenbergen, P.J., Vielsted Christensen, K., Potempa, K., Torleif Pedersen, J., Egebjerg, J., Kallunki, P., Nielsen, E.B., de Kloet, E.R., Didriksen, M. , Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility?, Psychopharmacology, vol. 217, no. 4, pp. 525-538. DOI
Daskalakis, N.P., Claessens, S.E., Laboyrie, J.J., Enthoven, L., Oitzl, M.S., Champagne, D.L., de Kloet, E.R. , The newborn rat's stress system readily habituates to repeated and prolonged maternal separation, while continuing to respond to stressors in context dependent fashion, Horm Behav, vol. 60, no. 2, pp. 165-176. DOI
Veen, G., van Vliet, I.M., De Rijk, R.H., Giltay, E.J., van Pelt, J., Zitman, F.G. , Basal cortisol levels in relation to dimensions and DSM-IV categories of depression and anxiety, Psychiatry Res, vol. 185, no. 1-2, pp. 121-128. DOI
Kuribara, M., Jenks, B.G., Dijkmans, T.F., de Gouw, D., Ouwens, D.T., Roubos, E.W., Vreugdenhil, E., Scheenen, W.J. , ERK-Regulated Double Cortin-Like Kinase (DCLK)-Short Phosphorylation and Nuclear Translocation Stimulate POMC Gene Expression in Endocrine Melanotrope Cells, Endocrinology, vol. 152, no. 6, pp. 2321-2329. DOI
Daskalakis, N.P., Martens, G.J., Cools, A.R., de Kloet, E.R. , Schizophrenia endophenotypes and stress hyper-reactivity co-precipitate following adverse life events in genetically susceptible rats, European Neuropsychopharmacology, vol. 21, pp. S85-S86. DOI
Ali, S., Champagne, D.L., Spaink, H.P., Richardson, M.K. , Zebrafish embryos and larvae: a new generation of disease models and drug screens, Birth Defects Res C Embryo Today, vol. 93, no. 2, pp. 115-133. DOI
van der Veen, D.R., Saaltink, D.J., Gerkema, M.P. , Behavioral Responses to Combinations of Timed Light, Food Availability, and Ultradian Rhythms in the Common Vole (Microtus arvalis), Chronobiol Int, vol. 28, no. 7, pp. 563-571. DOI
Schwabe, L., Joels, M., Roozendaal, B., Wolf, O.T., Oitzl, M.S. , Stress effects on memory: An update and integration, Neurosci Biobehav Rev. DOI
Groeneweg, F.L., Karst, H., de Kloet, E.R., Joels, M. , Rapid non-genomic effects of corticosteroids and their role in the central stress response, J Endocrinol, vol. 209, pp. 153-167. DOI
van Tijn, P., Hobo, B., Verhage, M.C., Oitzl, M.S., van Leeuwen, F.W., Fischer, D.F. , Alzheimer-associated mutant ubiquitin impairs spatial reference memory, Physiol Behav, vol. 102, no. 2, pp. 193-200. DOI
Bertsch, K., Bohnke, R., Kruk, M.R., Richter, S., Naumann, E. , Exogenous cortisol facilitates responses to social threat under high provocation, Horm Behav, vol. 59, no. 4, pp. 428-434. DOI
Klok, M.D., Alt, S.R., Irurzun Lafitte, A.J., Turner, J.D., Lakke, E.A., Huitinga, I, Muller, C.P., Zitman, F.G., de Kloet, E.R., De Rijk, R.H. , Decreased expression of mineralocorticoid receptor mRNA and its splice variants in postmortem brain regions of patients with major depressive disorder, J Psychiatr Res, vol. 45, no. 7, pp. 871-878. DOI
Schenk, G.J., Vreugdenhil, E., Hubens, C.J., Veldhuisen, B., de Kloet, E.R., Oitzl, M.S. , Hippocampal CARP over-expression solidifies consolidation of contextual fear memories, Physiol Behav, vol. 102, no. 3-4, pp. 323-331. DOI
Claessens, S.E., Daskalakis, N.P., van der Veen, R., Oitzl, M.S., de Kloet, E.R., Champagne, D.L. , Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences, Psychopharmacology, vol. 214, no. 1, pp. 141-154. DOI
Richter, S., Schulz, A., Zech, C.M., Oitzl, M.S., Daskalakis, N.P., Blumenthal, T.D., Schachinger, H. , Cortisol rapidly disrupts prepulse inhibition in healthy men, Psychoneuroendocrinology, vol. 36, no. 1, pp. 109-114. DOI
Spijker, A.T., Giltay, E.J., van Rossum, E.F., Manenschijn, L., de Rijk, R.H., Haffmans, J., Zitman, F.G., Hoencamp, E. , Glucocorticoid and mineralocorticoid receptor polymorphisms and clinical characteristics in bipolar disorder patients, Psychoneuroendocrinology. DOI
Llorente, R., Miguel-Blanco, C., Aisa, B., Lachize, S., Borcel, E., Meijer, O.C., Ramirez, M.J., De Kloet, E.R., Viveros, M.P. , Long term sex-dependent psychoneuroendocrine effects of maternal deprivation and juvenile unpredictable stress in rats, J Neuroendocrinol, vol. 23, no. 4, pp. 329-344. DOI
Hendriks, M.L., Lambalk, C.B., Helder, M.N., de Koning, J. , Purification of a candidate gonadotrophin surge-inhibiting/attenuating factor (GnSIF/AF) showing MAPK as a possible target, Mol Reprod Dev, vol. 78, no. 4, pp. 292-304. DOI
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2008
van der Laan, S., Sarabdjitsingh, R.A., Van Batenburg, M.F., Lachize, S.B., Li, H., Dijkmans, T.F., Vreugdenhil, E., de Kloet, E.R., Meijer, O.C. , Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain, J Neurochem, vol. 106, no. 6, pp. 2515-2523. DOI
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2007
Schmidt, M.V., Oitzl, M.S., Steenbergen, P.J., Lachize, S.B., Wurst, W., Muller, M.B., de Kloet, E.R., Meijer, O.C. , Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function, Brain Res, vol. 1174, pp. 1-6. DOI
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Sibug, R.M., Datson, N.A., Tijssen, A.M., Morsink, M.C., de Koning, J., de Kloet, E.R., Helmerhorst, F.M. , Effects of urinary and recombinant gonadotrophins on gene expression profiles during the murine peri-implantation period, Hum Reprod, vol. 22, no. 1, pp. 75-82. DOI
Klok, M.D., Jakobsdottir, S., Drent, M.L. , The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review, Obes Rev, vol. 8, no. 1, pp. 21-34. DOI
de Jong, I.E., Oitzl, M.S., de Kloet, E.R. , Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner, Behav Brain Res, vol. 177, no. 2, pp. 329-339. DOI
de Kloet, E.R., De Rijk, R.H., Meijer, O.C. , Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?, Nat Clin Pract Endocrinol Metab, vol. 3, no. 2, pp. 168-179. DOI
Schenk, G.J., Engels, B.M., Zhang, Y.P., Fitzsimons, C.P., Schouten, T., Kruidering, M., de Kloet, E.R., Vreugdenhil, E. , A potential role for calcium / calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence, Eur J Neurosci, vol. 26, no. 12, pp. 3411-3420. DOI
Oomen, C.A., Mayer, J.L., de Kloet, E.R., Joels, M., Lucassen, P.J. , Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress, Eur J Neurosci, vol. 26, no. 12, pp. 3395-3401. DOI
Enthoven, L. , Early life experience: neuroendocrine adaptations to maternal absence, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Morsink, M.C. , Glucocorticoid control of gene transcription in neural tissue, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
de Jong, I.E.M. , Vulnerability to cocaine: role of stress hormones, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
de Kloet, E.R. , Commentary: neuroendocrine basis, Prog Brain Res, vol. 167, pp. 53-62. DOI
Oitzl, M.S. , Commentary: behavioral phenotype, Prog Brain Res, vol. 167, pp. 111-117. DOI
Vreugdenhil, E., de Rijk, R.H. , Stressgenen en genetische variaties: implicaties voor hersenfuncties, Neuropraxis, vol. 11, no. 3, pp. 77-83. DOI
Oitzl, M.S. , Avoidance, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 297-301. DOI
Glas, C.A.W., Korobko, O.B. , A Marginal Maximum Likelihood Procedure for an IRT Model with Single-Peaked Response Functions, OMD Progress Report 07-01, vol. 07, no. 01, pp. 1-10.
Meijer, O.C., De Kloet, E.R., McEwen, B.S. , Corticosteroid Receptors, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 594-605. DOI
Brinks, V., van der Mark, M.H., de Kloet, E.R., Oitzl, M.S. , Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition, Neural Plast, vol. 2007, no. Articlr ID, pp. 1-11. DOI
Datson, N.A., Morsink, M.C., Atanasova, S., Armstrong, V.W., Zischler, H., Schlumbohm, C., Dutilh, B.E., Huynen, M.A., Waegele, B., Ruepp, A., de Kloet, E.R., Fuchs, E. , Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate, BMC Genomics, vol. 8, no. 190, pp. 1-9. DOI
Gorter, J.A., van Vliet, E.A., Rauwerda, H., Breit, T., Stad, R., van Schaik, L., Vreugdenhil, E., Redeker, S., Hendriksen, E., Aronica, E., Lopes da Silva, F.H., Wadman, W.J. , Dynamic changes of proteases and protease inhibitors revealed by microarray analysis in CA3 and entorhinal cortex during epileptogenesis in the rat, Epilepsia, vol. 48, no. Suppl-5, pp. 53-64. DOI
Vreugdenhil, E., Kolk, S.M., Boekhoorn, K., Fitzsimons, C.P., Schaaf, M.J., Schouten, T., Sarabdjitsingh, R.A., Sibug, R.M., Lucassen, P.J. , Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability, Eur J Neurosci, vol. 25, no. 3, pp. 635-648. DOI
Zitman, F.G., Vreeburg, S., Kruijtzer, B., van Pelt, H., van Dyck, R., de Rijk, R.H., Hoogendijk, W., Penninx, B. , Depression and HPA-axis dysregulation: A large cohort study, Eur Psychiatry, vol. 22, pp. S25-S25. DOI
Fink, G. , Encyclopedia of stress, , vol. 2nd: Elsevier / Academic Press.
Datson, N.A., Morsink, M.C. , Expression Profiling of Stress Responsive Gene Patterns, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 986-991. DOI
Brinks, V., van der Mark, M.H., De Kloet, E.R., Oitzl, M.S. , Emotion and cognition in high and low stress sensitive mouse strains: a combined neuroendocrine and behavioral study in BALB/c and C57BL/6J mice, Front Behav Neurosci, vol. 1, no. 8, pp. 1-12. DOI
Vos, J.B., Datson, N.A., Rabe, K.F., Hiemstra, P.S. , Exploring host-pathogen interactions at the epithelial surface: application of transcriptomics in lung biology, Am J Physiol Lung Cell Mol Physiol, vol. 292, no. 2, pp. L367-L377. DOI
Sonneveld, E., Jonas, A., Meijer, O.C., Brouwer, A., van der Burg, B. , Glucocorticoid-Enhanced Expression of Dioxin Target Genes through Regulation of the Rat Aryl Hydrocarbon Receptor, Toxicol Sci, vol. 99, no. 2, pp. 455-469. DOI
de Rijk, R.H., De Kloet, E.R. , Mineralocorticoid Receptor Polymorphisms, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 744-748. DOI
Kuningas, M., de Rijk, R.H., Westendorp, R.G., Jolles, J., Slagboom, P.E., van Heemst, D. , Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors, Neuropsychopharmacology, vol. 32, no. 6, pp. 1295-1301. DOI
De Kloet, E.R., Rinne, T. , Neuroendocrine markers of early trauma : implications for posttraumatic stress disorders, Traumatic dissociation neurobiology and treatment, vol. 1st ed, Washington, DC, American Psychiatric Pub, pp. 139-156.
Revsin, Y., Oitzl, M.S., Saravia, F.E., De Nicola, A.E., De Kloet, E.R. , Neuroendocrine markers in streptozotocin (STZ)-induced type 1 diabetes, Diabetologia, vol. 50, pp. S282-S283, 0684. DOI
Bemelmans, K.J., Noort, A., de Rijk, R.H., Middelkoop, H.A.M., van Kempen, G.M.J., Goekoop, J.G. , Plasma cortisol and norepinephrine in Alzheimer's disease: opposite relations with recall performance and stage of progression, Acta Neuropsychiatrica, vol. 19, no. 4, pp. 231-237. DOI
Kap, Y.S., Hoozemans, J.J., Bodewes, A.J., Zwart, R., Meijer, O.C., Baas, F., Scheper, W. , Pin1 levels are downregulated during ER stress in human neuroblastoma cells, Neurogenetics, vol. 8, no. 1, pp. 21-27. DOI
De Kloet, E.R., Oitzl, M.S., Vermetten, E. , Stress hormones and post traumatic stress disorder basic studies and clinical perspectives, Prog Brain Res, vol. 167, no. xviii, 320, Amsterdam, Elsevier, pp. 1-320. DOI
Brinks, V., de Kloet, E.R., Oitzl, M.S. , Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice, Stress Hormones and Post Traumatic Stress Disorder: Basic Studies and Clinical Perspectives, vol. 167, Amsterdam, Elsevier Science Bv, pp. 257-261. DOI
De Kloet, E.R. , Stress System Balance Hypothesis, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 646-650. DOI
Helmerhorst, F.M., Sibug, R.M., De Kloet, E.R. , Stress Effect of Assisted Reproduction, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 596-598. DOI
Karssen, A.M., De Kloet, E.R. , Synthetic Glucocorticoids, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 704-708. DOI
Levine, S., De Kloet, E.R., Dent, G., Schmidt, M.V. , Stress Hyporesponsive Period, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 606-611. DOI
De Kloet, E.R. , Susceptibility or resilience to psychopathology? A question of stress, genes and balance, Eur Neuropsychopharmacol, vol. 17, pp. S173-S173. DOI
Schwabe, L., Oitzl, M.S., Philippsen, C., Richter, S., Bohringer, A., Wippich, W., Schachinger, H. , Stress modulates the use of spatial versus stimulus-response learning strategies in humans, Learn Mem, vol. 14, no. 1, pp. 109-116. DOI
Van Eekelen, J.A.M., Mattes, E., Foster, J.K., De Kloet, E.R., McKeague, I.W. , The effects of HPA development on adolescent brain maturation, Early Human Development, vol. 83, pp. S122-S123, P1-140. DOI
Veen, G., Van Vliet, I.M., de Rijk, R.H., Zitman, F.G. , The cortisol awakening response in mood, anxiety and somatoform disorders - additional impact of severity and sleep quality, Eur Neuropsychopharmacol, vol. 17, pp. S308-S309. DOI
2006
van Gemert, N.G., Meijer, O.C., Morsink, M.C., Joels, M. , Effect of brief corticosterone administration on SGK1 and RGS4 mRNA expression in rat hippocampus, Stress, vol. 9, no. 3, pp. 165-170. DOI
Schmidt, M.V., Deussing, J.M., Oitzl, M.S., Ohl, F., Levine, S., Wurst, W., Holsboer, F., Muller, M.B., de Kloet, E.R. , Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice, Eur J Neurosci, vol. 24, no. 8, pp. 2291-2298. DOI
Lucassen, P.J., Heine, V.M., Muller, M.B., van der Beek, E.M., Wiegant, V.M., De Kloet, E.R., Joels, M., Fuchs, E., Swaab, D.F., Czeh, B. , Stress, depression and hippocampal apoptosis, CNS Neurol Disord Drug Targets, vol. 5, no. 5, pp. 531-546. DOI
van Leeuwen, N., Wust, S., Meijer, O.C., de Kloet, E.R., Zitman, F.G., de Rijk, R.H. , The role of single nucleotide polymorphisms (SNPs) in the mineralocorticoid receptor (MR) in stress response and psychopathology, American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, vol. 141B, no. 7, pp. 752-752. DOI
Schoonman, G.G., Evers, D.J., Ballieux, B.E., de Geus, E.J., de Kloet, E.R., Terwindt, G.M., van Dijk, J.G., Ferrari, M.D. , Is stress a trigger factor for migraine?, Cephalalgia, vol. 26, no. 11, pp. 1384-1385. DOI
Schmidt, M.V., Levine, S., Alam, S., Harbich, D., Sterlemann, V., Ganea, K., de Kloet, E.R., Holsboer, F., Muller, M.B. , Metabolic signals modulate hypothalamic-pituitary-adrenal axis activation during maternal separation of the neonatal mouse, J Neuroendocrinol, vol. 18, no. 11, pp. 865-874. DOI
Morsink, M.C., Joels, M., Sarabdjitsingh, R.A., Meijer, O.C., De Kloet, E.R., Datson, N.A. , The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells, J Neurochem, vol. 99, no. 4, pp. 1282-1298. DOI
Feldker, D.E., Morsink, M.C., Veenema, A.H., Datson, N.A., Proutski, V., Lathouwers, D., de Kloet, E.R., Vreugdenhil, E. , The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates, Brain Res, vol. 1089, no. 1, pp. 10-20. DOI
van Gemert, N.G., van Riel, E., Meijer, O.C., Fehr, S., Schachner, M., Joels, M. , No effect of prolonged corticosterone over-exposure on NCAM, SGK1, and RGS4 mRNA expression in rat hippocampus, Brain Res, vol. 1093, no. 1, pp. 161-166. DOI
Herbert, J., Goodyer, I.M., Grossman, A.B., Hastings, M.H., de Kloet, E.R., Lightman, S.L., Lupien, S.J., Roozendaal, B., Seckl, J.R. , Do corticosteroids damage the brain?, J Neuroendocrinol, vol. 18, no. 6, pp. 393-411. DOI
Saravia, F.E., Beauquis, J., Revsin, Y., Homo-Delarche, F., de Kloet, E.R., De Nicola, A.F. , Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment, Cell Mol Neurobiol, vol. 26, no. 4-6, pp. 943-957. DOI
Tjin, E.P., Groen, R.W., Vogelzang, I, Derksen, P.W., Klok, M.D., Meijer, H.P., van Eeden, S., Pals, S.T., Spaargaren, M. , Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma, Blood, vol. 107, no. 2, pp. 760-768. DOI
de Kloet, E.R. , From punch to profile, Neurochem Res, vol. 31, no. 2, pp. 131-135. DOI
De Rijk, R.H., Wust, S., Meijer, O.C., Zennaro, M.C., Federenko, I.S., Hellhammer, D.H., Giacchetti, G., Vreugdenhil, E., Zitman, F.G., de Kloet, E.R. , A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness, J Clin Endocrinol Metab, vol. 91, no. 12, pp. 5083-5089. DOI
Mayer, J.L., Klumpers, L., Maslam, S., de Kloet, E.R., Joels, M., Lucassen, P.J. , Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis, J Neuroendocrinol, vol. 18, no. 8, pp. 629-631. DOI
Morsink, M.C., Steenbergen, P.J., Vos, J.B., Karst, H., Joels, M., De Kloet, E.R., Datson, N.A. , Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time, J Neuroendocrinol, vol. 18, no. 4, pp. 239-252. DOI
Gabor, K., Verissimo, C.S., Cyran, B.C., Ter Horst, P., Meijer, N.P., Smidt, H., de Vos, W.M., van der Oost, J. , Characterization of CprK1, a CRP/FNR-type transcriptional regulator of halorespiration from Desulfitobacterium hafniense, Journal of Bacteriology, vol. 188, no. 7, pp. 2604-2613. DOI
Bekker, M.N., van den Akker, N.M., Bartelings, M.M., Arkesteijn, J.B., Fischer, S.G., Polman, J.A., Haak, M.C., Webb, S., Poelmann, R.E., van Vugt, J.M., Gittenberger-de Groot, A.C. , Nuchal edema and venous-lymphatic phenotype disturbance in human fetuses and mouse embryos with aneuploidy, J Soc Gynecol Investig, vol. 13, no. 3, pp. 209-216. DOI
Kruk, M.R., de Kloet, E.R., Meelis, W., Halasz, J., Mikics, E., Haller, J. , Corticosteroids curiously change current and coming conflicts, ISRA XVII World Meeting, Minneapolis, Minnesota, USA.
Haller, J., Mikics, E., Toth, M., Halasz, J., Kruk, M.R. , Normal and abnormal aggression: human disorders and novel laboratory models, ISRA XVII World Meeting, Minneapolis, Minnesota, USA.
Vos, J.B., Datson, N.A., van Kampen, A.H., Luyf, A.C., Verhoosel, R.M., Zeeuwen, P.L., Olthuis, D., Rabe, K.F., Schalkwijk, J., Hiemstra, P.S. , A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes, BMC Genomics, vol. 7, no. 1, pp. 1-9. DOI
Wright, R.L., Lightner, E.N., Harman, J.S., Meijer, O.C., Conrad, C.D. , Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory, Eur J Neurosci, vol. 24, no. 2, pp. 595-605. DOI
De Kloet, E.R., Oitzl, M.S. , Cortisol and PTSD: Animal Experiments and Clinical Perspectives, PTSD, brain mechanisms and clinical implications, no. Part 1, New York, Springer, pp. 13-27.
Goekoop, J.G., de Winter, R.P., de Rijk, R.H., Zwinderman, K.H., Frankhuijzen-Sierevogel, A., Wiegant, V.M. , Depression with above-normal plasma vasopressin: validation by relations with family history of depression and mixed anxiety and retardation, Psychiatry Res, vol. 141, no. 2, pp. 201-211. DOI
Steigenga, M.J., Helmerhorst, F.M., de Koning, J., Tijssen, A.M. I, Ruinard, S.A.T., Galis, F. , Evolutionary conserved structures as indicators of medical risks: increased incidence of cervical ribs after ovarian hyperstimulation in mice, Animal Biology, vol. 56, no. 1, pp. 63-68. DOI
Jeurissen, S.M., Bogaards, J.J., Boersma, M.G., Ter Horst, J.P., Awad, H.M., Fiamegos, Y.C., van Beek, T.A., Alink, G.M., Sudholter, E.J., Cnubben, N.H., Rietjens, I.M. , Human cytochrome p450 enzymes of importance for the bioactivation of methyleugenol to the proximate carcinogen 1'-hydroxymethyleugenol, Chem Res Toxicol, vol. 19, no. 1, pp. 111-116. DOI
Revsin, Y., van Wijk, D., Saravia, F.E., De Nicola, A.F., Oitzl, M.S., De Kloet, E.R. , HPA axis regulation reaches a new setpoint in acute and chronic type 1 diabetes: implications for brain pathology, Diabetologia, vol. 49, pp. 329-330. DOI
Joels, M., Pu, Z., Wiegert, O., Oitzl, M.S., Krugers, H.J. , Learning under stress: how does it work?, Trends Cogn Sci, vol. 10, no. 4, pp. 152-158. DOI
Hoekstra, M., Stitzinger, M., van Wanrooij, E.J., Michon, I.N., Kruijt, J.K., Kamphorst, J., Van Eck, M., Vreugdenhil, E., Van Berkel, T.J., Kuiper, J. , Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet, J Lipid Res, vol. 47, no. 10, pp. 2198-2207. DOI
De Kloet, E.R. , Neurodevelopmental setpoint and vulnerability to disease, Eur Neuropsychopharmacol, vol. 16, pp. S202-S202. DOI
Haller, J., Kruk, M.R. , Normal and abnormal aggression: human disorders and novel laboratory models, Neurosci Biobehav Rev, vol. 30, no. 3, pp. 292-303. DOI
de Rijk, R.H., De Kloet, E.R. , Stress, glucocorticoids, and the brain, Nutrients, stress, and medical disorders, Totowa, N.J, Humana Press, pp. 111-135. DOI
de Jong, I.E.M., van den Buuse, M. , SCH 23390 in the prefrontal cortex enhances the effect of apomorphine on prepulse inhibition of rats, Neuropharmacology, vol. 51, no. 3, pp. 438-446. DOI
De Kloet, E.R., Sibug, R.M., Helmerhorst, F.M., Schmidt, M.V. , Stress, genes and the mechanism of programming the brain for later life (vol 29, pg 271, 2005), Neurosci Biobehav Rev, vol. 30, no. 4, pp. 576-576. DOI
Meijer, O.C., van der Laan, S., Lachize, S.B., Steenbergen, P.J., de Kloet, E.R. , Steroid receptor coregulator diversity: what can it mean for the stressed brain?, Neuroscience, vol. 138, no. 3, pp. 891-899. DOI
Schmidt, M.V., Enthoven, L., van der Mark, M.H., Levine, S., De Kloet, E.R., Oitzl, M.S. , The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse (vol 23, pg 125, 2003), Int J Dev Neurosci, vol. 24, no. 4, pp. 293-293. DOI
Meijer, O.C. , Understanding stress through the genome, Stress, vol. 9, no. 2, pp. 61-67. DOI
2005
van der Laan, S., Lachize, S.B., Schouten, T.G., Vreugdenhil, E., de Kloet, E.R., Meijer, O.C. , Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain, Brain Res, vol. 1059, no. 2, pp. 113-121. DOI
Revsin, Y., Saravia, F., Roig, P., Lima, A., de Kloet, E.R., Homo-Delarche, F., De Nicola, A.F. , Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes, Brain Res, vol. 1038, no. 1, pp. 22-31. DOI
Veenema, A.H., Cremers, T.I.F.H., Jongsma, M.E., Steenbergen, P.J., de Boer, S.F., Koolhaas, J.M. , Differences in the effects of 5-HT1A receptor agonists on forced swimming behavior and brain 5-HT metabolism between low and high aggressive mice, Psychopharmacology, vol. 178, no. 2-3, pp. 151-160. DOI
Schmidt, M.V., Levine, S., Oitzl, M.S., van der Mark, M.H., Muller, M.B., Holsboer, F., de Kloet, E.R. , Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse, Endocrinology, vol. 146, no. 3, pp. 1458-1464. DOI
Meijer, O.C., Kalkhoven, E., van der Laan, S., Steenbergen, P.J., Houtman, S.H., Dijkmans, T.F., Pearce, D., de Kloet, E.R. , Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling, Endocrinology, vol. 146, no. 3, pp. 1438-1448. DOI
Sibug, R.M., de Koning, J., Tijssen, A.M., de Ruiter, M.C., de Kloet, E.R., Helmerhorst, F.M. , Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period, Hum Reprod, vol. 20, no. 3, pp. 649-656. DOI
de Kloet, E.R., Joels, M., Holsboer, F. , Stress and the brain: from adaptation to disease, Nat Rev Neurosci, vol. 6, no. 6, pp. 463-475. DOI
Veenema, A.H., Sijtsma, B., Koolhaas, J.M., de Kloet, E.R. , The stress response to sensory contact in mice: genotype effect of the stimulus animal, Psychoneuroendocrinology, vol. 30, no. 6, pp. 550-557. DOI
De Rijk, R.H., de Kloet, E.R. , Corticosteroid receptor genetic polymorphisms and stress responsivity, Endocrine, vol. 28, no. 3, pp. 263-270. DOI
Karssen, A.M., Meijer, O.C., Berry, A., Sanjuan Pinol, R., de Kloet, E.R. , Low doses of dexamethasone can produce a hypocorticosteroid state in the brain, Endocrinology, vol. 146, no. 12, pp. 5587-5595. DOI
de Kloet, E.R., Sibug, R.M., Helmerhorst, F.M., Schmidt, M.V. , Stress, genes and the mechanism of programming the brain for later life, Neurosci Biobehav Rev, vol. 29, no. 2, pp. 271-281. DOI
Engels, B.M. , Expression and functional characterization of DoubleCortin-Like Kinase (DCLK) splice variants, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 175.
Dalm, S., Enthoven, L., Meijer, O.C., van der Mark, M.H., Karssen, A.M., de Kloet, E.R., Oitzl, M.S. , Age-related changes in hypothalamic-pituitary-adrenal axis activity of male C57BL/6J mice, Neuroendocrinology, vol. 81, no. 6, pp. 372-380. DOI
Wust, S., de Rijk, R.H., Meijer, O.C., Federenko, I, Vreugdenhil, E., de Punder, K., Hellhammer, D., De Kloet, E.R. , A common mineralocorticoid receptor gene variant is associated with cortisol and heart rate response to psychosocial stress, J Psychophysiology, vol. 19, no. 2, pp. 154-155. DOI
De Kloet, E.R., Schmidt, M.V., Meijer, O.C. , Corticosteroid receptors and HPA axis regulation, Handbook of stress and the brain, vol. 1, Amsterdam, Elsevier, pp. 265-295.
Karssen, A.M., Meijer, O.C., de Kloet, E.R. , Corticosteroids and the blood-brain barrier, Handbook of stress and the brain, vol. 1, Amsterdam, Elsevier, pp. 329-341.
Meijer, O.C., Topic, B., Steenbergen, P.J., Jocham, G., Huston, J.P., Oitzl, M.S. , Correlations between hypothalamus-pituitary-adrenal axis parameters depend on age and learning capacity, Endocrinology, vol. 146, no. 3, pp. 1372-1381. DOI
Kruk, M.R., De Kloet, E.R. , Genen, glucocortico‹den en geweld, Tijdschrift voor Criminologie, vol. 47, no. 2, pp. 136-141.
Revsin, Y., Dalm, S., Saravia, F.E., Oitzl, M.S., De Nicola, A.F., De Kloet, E.R. , HPA axis regulation in type 1 diabetes, Diabetologia, vol. 48, pp. A234-A234.
Ingram, N., Martin, S., Wang, J.H., van der Laan, S., Loiacono, R., van den Buuse, M. , Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice, Neuropharmacology, vol. 48, no. 1, pp. 80-92. DOI
Schmidt, M.V., Oitzl, M.S., Muller, M.B., Ohl, F., Wurst, W., Holsboer, F., Levine, S., De Kloet, E.R. , Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice (vol 119, pg 589, 2003), Neuroscience, vol. 135, no. 4, pp. 1343-1343. DOI
De Kloet, E.R. , Stress, cortisol and cognition: Towards understanding a vulnerable phenotype for stress-related psychopathology, Nordic Journal of Psychiatry, vol. 59, no. 5, pp. 398-398. DOI
Oitzl, M.S., Enthoven, L., De Kloet, E.R. , Stress system regulation, glucocorticoid receptors and traumatic early life events, Eur Psychiatry, vol. 20, no. Suppl-1, pp. S102-S102. DOI
Schmidt, M.V., Oitzl, M.S., Levine, S., De Kloet, E.R. , The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation (vol 139, pg 39, 2002), Developmental Brain Research, vol. 160, no. 2, pp. 287-287. DOI
Vos, J.B., van Sterkenburg, M.A., Rabe, K.F., Schalkwijk, J., Hiemstra, P.S., Datson, N.A. , Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense, Physiol Genomics, vol. 21, no. 3, pp. 324-336. DOI
van Overveld, P.G., Enthoven, L., Ricci, E., Rossi, M., Felicetti, L., Jeanpierre, M., Winokur, S.T., Frants, R.R., Padberg, G.W., van der Maarel, S.M. , Variable hypomethylation of D4Z4 in facioscapulohumeral muscular dystrophy, Ann Neurol, vol. 58, no. 4, pp. 569-576. DOI
2004
Datson, N.A., Meijer, L., Steenbergen, P.J., Morsink, M.C., van der Laan, S., Meijer, O.C., de Kloet, E.R. , Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression, Eur J Neurosci, vol. 20, no. 10, pp. 2541-2554. DOI
Veenema, A.H., Koolhaas, J.M., de Kloet, E.R. , Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines, Ann N Y Acad Sci, vol. 1018, pp. 255-265. DOI
de Jong, I.E., de Kloet, E.R. , Glucocorticoids and vulnerability to psychostimulant drugs: toward substrate and mechanism, Ann N Y Acad Sci, vol. 1018, pp. 192-198. DOI
De Kloet, E.R. , Hormones and the stressed brain, Ann N Y Acad Sci, vol. 1018, pp. 1-15. DOI
van Riel, E., van Gemert, N.G., Meijer, O.C., Joels, M. , Effect of early life stress on serotonin responses in the hippocampus of young adult rats, Synapse, vol. 53, no. 1, pp. 11-19. DOI
Grootendorst, J., Enthoven, L., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice, Behav Brain Res, vol. 148, no. 1-2, pp. 167-177. DOI
Schmidt, M.V., Enthoven, L., van Woezik, J.H., Levine, S., de Kloet, E.R., Oitzl, M.S. , The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation, J Neuroendocrinol, vol. 16, no. 1, pp. 52-57. DOI
Karssen, A.M., Meijer, O.C., Pons, D., De Kloet, E.R. , Localization of mRNA expression of P-glycoprotein at the blood-brain barrier and in the hippocampus, Ann N Y Acad Sci, vol. 1032, pp. 308-311. DOI
Derksen, P.W., Tjin, E., Meijer, H.P., Klok, M.D., MacGillavry, H.D., van Oers, M.H., Lokhorst, H.M., Bloem, A.C., Clevers, H., Nusse, R., van der Neut, R., Spaargaren, M., Pals, S.T. , Illegitimate WNT signaling promotes proliferation of multiple myeloma cells, PNAS, vol. 101, no. 16, pp. 6122-6127. DOI
Enthoven, L., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Swim posture of mice does not affect performance in the water maze, Brain Res, vol. 1003, no. 1-2, pp. 36-41. DOI
Blain, J.F., Paradis, E., Gaudreault, S.B., Champagne, D.L., Richard, D., Poirier, J. , A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain, Neurobiol Dis, vol. 15, no. 3, pp. 510-9. DOI
Kruk, M.R., Halasz, J., Mikics, E., Meelis, W., Haller, J. , Corticosteroid Feedback to the Brain Tips the Flight-Fight Balance in the Brain towards Aggression, ISRA XVI World Meeting, Santorini, Greece.
Schmidt, M.V. , Stress system development: Molecular mechanisms of activation and inhibition, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 186.
De Kloet, E.R. , Corticosteroiden, Farmacologie, Utrecht, Wetenschappelijke Uitgeverij Bunge, pp. 212-224.
De Kloet, E.R., Karssen, A.M., Meijer, O.C., Oitzl, M.S. , Central effects of glucocorticoid antagonists: Preclinical studies, Biol Psychiatry, vol. 55, no. 8, Suppl-1, pp. 190S-191S. DOI
Haller, J., Halasz, J., Mikics, E., Kruk, M.R. , Chronic glucocorticoid deficiency-induced abnormal aggression, autonomic hypoarousal, and social deficit in rats, J Neuroendocrinol, vol. 16, no. 6, pp. 550-557. DOI
Engels, B.M., Schouten, T.G., van Dullemen, J., Gosens, I, Vreugdenhil, E. , Functional differences between two DCLK splice variants, Brain Res Mol Brain Res, vol. 120, no. 2, pp. 103-114. DOI
Kruk, M.R., Halasz, J., Meelis, W., Haller, J. , Fast positive feedback between the adrenocortical stress response and a brain mechanism involved in aggressive behavior, Behav Neurosci, vol. 118, no. 5, pp. 1062-1070. DOI
de Jong, I.E.M., Oitzl, M.S., De Kloet, E.R. , Genetic background and glucocorticoid hormones contribute to individual differences in sensitivity of mice to cocaine, Behavioural Pharmacology, vol. 15, no. 5-6, pp. A13-A13.
Mikics, E., Kruk, M.R., Haller, J. , Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats, Psychoneuroendocrinology, vol. 29, no. 5, pp. 618-635. DOI
Cullen, P., Lorkowski, S., Bauer, O., Guerasimova, A., Lehrach, H., Janitz, M., Herwig, R., Radelof, U., Panter, W., Harrington, J., Lorkowski, G., Amit, A., Bickel, R., Wagenhaus, A., Ermantraut, E., Wagner, G., Leube, I., Sachtschal, J., Ehricht, R., Ellinger, T., Chen, Z.J., Tew, K.D., Gate, L., Davis, W., Lübbert, H., Fisher, J.S., Walden, J., Meade, J., Liang, P., Guo, Z., Shimkets, R.A., Okubo, , High-Throughput and Industrial Methods for mRNA Expression Analysis, Analysing Gene Expression: Wiley-VCH Verlag GmbH & Co. KGaA. DOI
Fauser, B.J.C.M., De Kloet, E.R., Lips, P., Michels, R.P.J., Wiersinga, W.M., Sitsen, J.M.A., van Wimersma Greidanus, T.B. , Hormonen, Farmacologie, Maarssen, Elsevier Gezondheidszorg.
Mulder, M., Jansen, P.J., Janssen, B.J., van de Berg, W.D., van der Boom, H., Havekes, L.M., De Kloet, E.R., Ramaekers, F.C., Blokland, A. , Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus, Neurobiol Dis, vol. 16, no. 1, pp. 212-219. DOI
de Rijk, R.H., Zitman, F.G., De Kloet, E.R. , Neuroendocrinologie van de stress respons, Handboek voor Neurobiologische Psychiatrie: De Tijdstroom, pp. 65-85.
van der Beek, E.M., Wiegant, V.M., Schouten, W.G., van Eerdenburg, F.J., Loijens, L.W., van der Plas, C., Benning, M.A., de Vries, H., de Kloet, E.R., Lucassen, P.J. , Neuronal number, volume, and apoptosis of the left dentate gyrus of chronically stressed pigs correlate negatively with basal saliva cortisol levels, Hippocampus, vol. 14, no. 6, pp. 688-700. DOI
De Kloet, E.R. , Obituary: In Honour of David de Wied, Psychoneuroendocrinology, vol. 29, no. 7, pp. 823-824. DOI
Saravia, F.E., Revsin, Y., Lux-Lantos, V., Beauquis, J., Homo-Delarche, F., De Nicola, A.F. , Oestradiol restores cell proliferation in dentate gyrus and subventricular zone of streptozotocin-diabetic mice, J Neuroendocrinol, vol. 16, no. 8, pp. 704-710. DOI
Flugge, G., Van Kampen, M., Mijnster, M.J. , Perturbations in brain monoamine systems during stress, Cell Tissue Res, vol. 315, no. 1, pp. 1-14. DOI
Pacak, K. , Stress, current neuroendocrine and genetic approaches, Ann N Y Acad Sci, vol. 1018, no. xiv, 590 p, New York, New York Academy of Sciences. DOI
van Praag, H.M., De Kloet, E.R., van Os, J. , Stress, the brain and depression, , no. xii, 283 p, Cambridge, UK, Cambridge University Press. DOI
Heilbronner, U., Van Kampen, M., Flugge, G. , The alpha-2B adrenoceptor in the paraventricular thalamic nucleus is persistently upregulated by chronic psychosocial stress, Cell Mol Neurobiol, vol. 24, no. 6, pp. 815-831. DOI
Rinne, T., van den Brink, W., Goekoop, J., de Rijk, R.H., De Kloet, E.R. , The neuro-endocrine scars of childhood abuse in female borderline personality disorder patients, Eur Psychiatry, vol. 19, no. Suppl-1, pp. 1S-1S, S11.02. DOI
Sibug, R.M., de Koning, J., De Kloet, E.R., Helmerhorst, F.M. , VEGF(120) and its receptors Flt-1 and Flk-1 in the mouse uterus during the peri-implantation period are downregulated by urinary gonadotropins but not by recombinant gonadotropins, J Society for Gynecologic Investigation, vol. 11, no. Suppl-2, pp. 286A-286A. DOI
2003
Feldker, D.E., de Kloet, E.R., Kruk, M.R., Datson, N.A. , Large-scale gene expression profiling of discrete brain regions: potential, limitations, and application in genetics of aggressive behavior, Behav Genet, vol. 33, no. 5, pp. 537-48. DOI
Spaargaren, M., Beuling, E.A., Rurup, M.L., Meijer, H.P., Klok, M.D., Middendorp, S., Hendriks, R.W., Pals, S.T. , The B cell antigen receptor controls integrin activity through Btk and PLCgamma2, J Exp Med, vol. 198, no. 10, pp. 1539-1550. DOI
Bredy, T.W., Grant, R.J., Champagne, D.L., Meaney, M.J. , Maternal care influences neuronal survival in the hippocampus of the rat, Eur J Neurosci, vol. 18, no. 10, pp. 2903-9. DOI
de Kloet, E.R., Oitzl, M.S. , Who cares for a stressed brain? The mother, the kid or both?, Neurobiol Aging, vol. 24 Suppl 1, pp. S61-5; discussion S67-8. DOI
Schmidt, M.V., Enthoven, L., van der Mark, M.H., Levine, S., de Kloet, E.R., Oitzl, M.S. , The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse, Int J Dev Neurosci, vol. 21, no. 3, pp. 125-132. DOI
Veenema, A.H., Meijer, O.C., de Kloet, E.R., Koolhaas, J.M. , Genetic selection for coping style predicts stressor susceptibility, J Neuroendocrinol, vol. 15, no. 3, pp. 256-67. DOI
de Kloet, E.R. , Hormones, brain and stress, Endocr Regul, vol. 37, no. 2, pp. 51-68.
Meijer, O.C., Karssen, A.M., de Kloet, E.R. , Cell- and tIssue-specific effects of corticosteroids in relation to glucocorticoid resistance: examples from the brain, J Endocrinol, vol. 178, no. 1, pp. 13-18. DOI
Veenema, A.H., Meijer, O.C., de Kloet, E.R., Koolhaas, J.M., Bohus, B.G. , Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression, Horm Behav, vol. 43, no. 1, pp. 197-204. DOI
Rinne, T., de Kloet, E.R., Wouters, L., Goekoop, J.G., de Rijk, R.H., van den Brink, W. , Fluvoxamine reduces responsiveness of HPA axis in adult female BPD patients with a history of sustained childhood abuse, Neuropsychopharmacology, vol. 28, no. 1, pp. 126-132. DOI
Feldker, D.E., Datson, N.A., Veenema, A.H., Meulmeester, E., de Kloet, E.R., Vreugdenhil, E. , Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice, Eur J Neurosci, vol. 17, no. 2, pp. 379-387. DOI
Feldker, D.E., Datson, N.A., Veenema, A.H., Proutski, V., Lathouwers, D., De Kloet, E.R., Vreugdenhil, E. , GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications, J Neurosci Res, vol. 74, no. 5, pp. 701-16. DOI
De Rijk, R.H., Schaaf, M.J., Stam, F.J., de Jong, I.E., Swaab, D.F., Ravid, R., Vreugdenhil, E., Cidlowski, J.A., de Kloet, E.R., Lucassen, P.J. , Very low levels of the glucocorticoid receptor beta isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry, Brain Res Mol Brain Res, vol. 116, no. 1-2, pp. 17-26. DOI
Feldker, D.E.M. , Towards the molecular basis of individual differences in vulnerability to stress: Application of large scale gene expression profiling, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 188.
Karssen, A.M. , Glucocorticoid access to the brain: involvement of the efflux transporter P-glycoprotein, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 191.
Veenema, A.H. , Coping style and stressor susceptibility: neuroendocrine and neurochemical studies with genetically selected mouse lines, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Haller, J., Kruk, M.R. , Neuroendocrine Stress Responses and Aggression, Neurobiology of aggression: Understanding and preventing violence, Totowa, N.J, Humana Press, pp. 93-118. DOI
Arbesman, S., Enthoven, L., Monteiro, A. , Ancient Wings: animating the evolution of butterfly wing patterns, Biosystems, vol. 71, no. 3, pp. 289-295. DOI
de Winter, R.F., van Hemert, A.M., de Rijk, R.H., Zwinderman, K.H., Frankhuijzen-Sierevogel, A.C., Wiegant, V.M., Goekoop, J.G. , Anxious-retarded depression: relation with plasma vasopressin and cortisol, Neuropsychopharmacology, vol. 28, no. 1, pp. 140-147. DOI
Flugge, G., Van Kampen, M., Meyer, H., Fuchs, E. , Alpha2A and alpha2C-adrenoceptor regulation in the brain: alpha2A changes persist after chronic stress, Eur J Neurosci, vol. 17, no. 5, pp. 917-928. DOI
Jonker, D.M., van de Mheen, C., Eilers, P.H., Kruk, M.R., Voskuyl, R.A., Danhof, M. , Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat, Behav Neurosci, vol. 117, no. 5, pp. 1076-1085. DOI
Tolmacheva, E.A., Oitzl, M.S., Chepumov, S.A., van Luijtelaar, E.L.J.M. , Activity of the hypothalamus-pituitary-adrenal axis in female absence epileptic rats, Epilepsia, vol. 44, pp. 107-107. DOI
van Riel, E., Meijer, O.C., Steenbergen, P.J., Joels, M. , Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons, Neuroscience, vol. 120, no. 3, pp. 649-658. DOI
de Jong, I.E.M., Oitzl, M.S., De Kloet, E.R. , Differential effects of glucocorticoids on the dopaminergic reward system in two genetically distinct mouse strains, Behavioural Pharmacology, vol. 14, no. Suppl-1, pp. S78-S78.
Pfaff, D.W., Swaab, D.F., Finch, C.E., Kessler, R., Buitelaar, J.K., Heuser, I, Brosens, I, Slob, A.K., De Kloet, E.R., Goodwin, G.M. , Discussion to 'Sex differences in the hypothalamus in the different stages of human life' by Dick E Swaab et al, Neurobiol Aging, vol. 24, pp. Suppl-1, S17-S19. DOI
Toussaint, O., Heuser, I, Thijssen, J.H.H., Finch, C.E., Swaab, D.F., De Kloet, E.R., Saletu, B., De Wied, D. , Discussion to "Stress and the brain" by Isabella Heuser and Claas-Hinrich Lammers and "Stress and aging: theoretical and empirical challenges for interdisciplinary research" by Jacqui Smith, Neurobiol Aging, vol. 24, pp. S81-S82. DOI
Qin, Y., Nair, S., Karst, H., Vreugdenhil, E., Datson, N.A., Joels, M. , Gene expression changes in single dentate granule neurons after adrenalectomy of rats, Mol Brain Res, vol. 111, no. 1-2, pp. 17-23. DOI
van Overveld, P.G., Lemmers, R.J., Sandkuijl, L.A., Enthoven, L., Winokur, S.T., Bakels, F., Padberg, G.W., van Ommen, G.J., Frants, R.R., van der Maarel, S.M. , Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy, Nat Genet, vol. 35, no. 4, pp. 315-317. DOI
De Kloet, E.R. , Neurosteroïden, Ned Tijdschr Klin Chem, vol. 28, pp. 179-182.
Bemelmans, K.J., Goekoop, J.G., de Rijk, R.H., van Kempen, G.M. , Recall performance, plasma cortisol and plasma norepinephrine in normal human subjects, Biol Psychol, vol. 62, no. 1, pp. 1-15. DOI
Schmidt, M.V., Oitzl, M.S., Muller, M.B., Ohl, F., Wurst, W., Holsboer, F., Levine, S., De Kloet, E.R. , Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice, Neuroscience, vol. 119, no. 2, pp. 589-595. DOI
Champagne, D.L., Pearson, D., Dea, D., Rochford, J., Poirier, J. , The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease, Neuroscience, vol. 121, no. 1, pp. 99-110. DOI
2002
Grootendorst, J., Kempes, M.M., Lucassen, P.J., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Differential effect of corticosterone on spatial learning abilities in apolipoprotein E knockout and C57BL/6J mice, Brain Res, vol. 953, no. 1-2, pp. 281-285. DOI
Karssen, A.M., Meijer, O.C., van der Sandt, I.C., De Boer, A.G., De Lange, E.C., De Kloet, E.R. , The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone, J Endocrinol, vol. 175, no. 1, pp. 251-260. DOI
Sibug, R.M., Helmerhorst, F.M., Tijssen, A.M., de Kloet, E.R., de Koning, J. , Estrogen reduces vascular endothelial growth factor(164) expression in the mouse nucleus paraventricularis of the hypothalamus, Neurosci Lett, vol. 333, no. 3, pp. 199-202. DOI
Schmidt, M.V., Oitzl, M.S., Levine, S., de Kloet, E.R. , The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation, Brain Res Dev Brain Res, vol. 139, no. 1, pp. 39-49. DOI
de Kloet, E.R., Grootendorst, J., Karssen, A.M., Oitzl, M.S. , Gene x environment interaction and cognitive performance: animal studies on the role of corticosterone, Neurobiol Learn Mem, vol. 78, no. 3, pp. 570-7. DOI
De Rijk, R.H., Schaaf, M.J., de Kloet, E.R. , Glucocorticoid receptor variants: clinical implications, J Steroid Biochem Mol Biol, vol. 81, no. 2, pp. 103-22. DOI
Sibug, R.M., Helmerhorst, F.M., Tijssen, A.M., de Kloet, E.R., de Koning, J. , Gonadotrophin stimulation reduces VEGF(120) expression in the mouse uterus during the peri-implantation period, Hum Reprod, vol. 17, no. 6, pp. 1643-1648. DOI
van Acker, S.A., Oitzl, M.S., Fluttert, M.F., de Kloet, E.R. , Centrally regulated blood pressure response to vasoactive peptides is modulated by corticosterone, J Neuroendocrinol, vol. 14, no. 1, pp. 56-63. DOI
Rahmouni, K., Sibug, R.M., De Kloet, E.R., Barthelmebs, M., Grima, M., Imbs, J.L., De Jong, W. , Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension, Eur J Pharmacol, vol. 436, no. 3, pp. 207-16. DOI
van den Buuse, M., van Acker, S.A., Fluttert, M.F., de Kloet, E.R. , Involvement of corticosterone in cardiovascular responses to an open-field novelty stressor in freely moving rats, Physiol Behav, vol. 75, no. 1-2, pp. 207-15. DOI
Van Kampen, M., De Kloet, E.R., Flugge, G., Fuchs, E. , Blockade of glucocorticoid receptors with ORG 34116 does not normalize stress-induced symptoms in male tree shrews, Eur J Pharmacol, vol. 457, no. 2-3, pp. 207-16. DOI
Evans, S.J., Datson, N.A., Kabbaj, M., Thompson, R.C., Vreugdenhil, E., De Kloet, E.R., Watson, S.J., Akil, H. , Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis. Serial Analysis of Gene Expression, Eur J Neurosci, vol. 16, no. 3, pp. 409-413. DOI
Schaap, J. , Neurons of the mammalian circadian pacemaker: cellular and network properties, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Rinne, T. , The neuroendocrine scars of sustained childhood abuse in adult female borderline personality disorder, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
van Kampen, M. , Chronic psychosocial stress in male tree shrews: an animal model for depression, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 154.
Horvath, K.M., Hartig, W., van der Veen, R., Keijser, J.N., Mulder, J., Ziegert, M., Van der Zee, E.A., Harkany, T., Luiten, P.G.M. , 17 beta-estradiol enhances cortical cholinergic innervation and preserves synaptic density following excitotoxic lesions to the rat nucleus basalis magnocellularis, Neuroscience, vol. 110, no. 3, pp. 489-504. DOI
Champagne, D.L., Dupuy, J.B., Rochford, J., Poirier, J. , Apolipoprotein E knockout mice display procedural deficits in the Morris water maze: analysis of learning strategies in three versions of the task, Neuroscience, vol. 114, no. 3, pp. 641-54. DOI
De Kloet, E.R., Oitzl, M.S., Vreugdenhil, E. , Brain corticosteroid receptors and responsive genes: Targets for therapy of stress-related disorders, Br J Pharmacol, vol. 135, pp. Suppl, 401P.
Joels, M., Krugers, H.J., De Kloet, E.R. , Corticosteroid actions on electrical activity in the brain, Hormones, Brain and Behavior, vol. 3, San Diego, CA., USA, Academic Press/Elsevier-Science, pp. 601-626.
Meijer, O.C. , Coregulator proteins and corticosteroid action in the brain, J Neuroendocrinol, vol. 14, no. 6, pp. 499-505. DOI
Saravia, F.E., Pietranera, L., Lima, A., Roig, P., Revsin, Y., De Nicola, A.F. , Deoxycorticosterone stimulates the activity of nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase immunoreactivity in hypothalamic nuclei of rats, Neurosci Lett, vol. 329, no. 3, pp. 344-348. DOI
Halasz, J., Liposits, Z., Meelis, W., Kruk, M.R., Haller, J. , Hypothalamic attack area-mediated activation of the forebrain in aggression, Neuroreport, vol. 13, no. 10, pp. 1267-1270.
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Mulder, M., Janssen, B., Jansen, P., Van de Berg, W., Blokland, A., Havekes, L., De Kloet, E.R. , Impaired memory and reduced synaptic plasticity in low-density lipoprotein receptor-knockout mice, Neurobiol Aging, vol. 23, no. 1, pp. S244-S245. DOI
Saravia, F.E., Revsin, Y., Gonzalez Deniselle, M.C., Gonzalez, S.L., Roig, P., Lima, A., Homo-Delarche, F., De Nicola, A.F. , Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice, Brain Res, vol. 957, no. 2, pp. 345-353. DOI
Schmidt, M.V., Okimoto, D.K., Dent, G.W., Gordon, M.K., Levine, S. , Maternal regulation of the hypothalamic-pituitary-adrenal axis in the 20-day-old rat: consequences of laboratory weaning, J Neuroendocrinol, vol. 14, no. 6, pp. 450-457. DOI
Halasz, J., Liposits, Z., Kruk, M.R., Haller, J. , Neural background of glucocorticoid dysfunction-induced abnormal aggression in rats: involvement of fear- and stress-related structures, Eur J Neurosci, vol. 15, no. 3, pp. 561-569. DOI
Gijsman, H.J., Van Gerven, J.M., de Kam, M.L., Schoemaker, R.C., Pieters, M.S., Weemaes, M., de Rijk, R.H., van der Post, J., Cohen, A.F. , Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers, J Clin Psychopharmacol, vol. 22, no. 2, pp. 183-189.
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De Kloet, E.R. , Stress in the brain: implications for treatment of depression, Acta Neuropsychiatrica, vol. 14, no. 4, pp. 155-166. DOI
Van Kampen, M., Kramer, M., Hiemke, C., Flugge, G., Fuchs, E. , The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders, Stress, vol. 5, no. 1, pp. 37-46. DOI
2001
Van Acker, S.A., Fluttert, M.F., Sibug, R.M., De Kloet, E.R. , Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses to brief restraint stress, Eur J Pharmacol, vol. 430, no. 1, pp. 87-91. DOI
Oitzl, M.S., Reichardt, H.M., Joels, M., de Kloet, E.R. , Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory, PNAS, vol. 98, no. 22, pp. 12790-12795. DOI
Vreugdenhil, E., Engels, B.M., Middelburg, R., van Koningsbruggen, S., Knol, J., Veldhuisen, B., de Kloet, E.R. , Multiple transcripts generated by the DCAMKL gene are expressed in the rat hippocampus, Brain Res Mol Brain Res, vol. 94, no. 1-2, pp. 67-74. DOI
Schaaf, M.J., Workel, J.O., Lesscher, H.M., Vreugdenhil, E., Oitzl, M.S., de Kloet, E.R. , Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats, Brain Res, vol. 915, no. 2, pp. 227-33. DOI
Visser, J., Graffelman, W., Blauw, B., Haspels, I, Lentjes, E., de Kloet, E.R., Nagelkerken, L. , LPS-induced IL-10 production in whole blood cultures from chronic fatigue syndrome patients is increased but supersensitive to inhibition by dexamethasone, J Neuroimmunol, vol. 119, no. 2, pp. 343-349. DOI
Grootendorst, J., de Kloet, E.R., Vossen, C., Dalm, S., Oitzl, M.S. , Repeated exposure to rats has persistent genotype-dependent effects on learning and locomotor activity of apolipoprotein E knockout and C57Bl/6 mice, Behav Brain Res, vol. 125, no. 1-2, pp. 249-59. DOI
De Rijk, R.H., Schaaf, M.J., Turner, G., Datson, N.A., Vreugdenhil, E., Cidlowski, J., de Kloet, E.R., Emery, P., Sternberg, E.M., Detera-Wadleigh, S.D. , A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis, J Rheumatol, vol. 28, no. 11, pp. 2383-8.
Grootendorst, J., Oitzl, M.S., Dalm, S., Enthoven, L., Schachner, M., de Kloet, E.R., Sandi, C. , Stress alleviates reduced expression of cell adhesion molecules (NCAM, L1), and deficits in learning and corticosterone regulation of apolipoprotein E knockout mice, Eur J Neurosci, vol. 14, no. 9, pp. 1505-1514. DOI
van den Buuse, M., Van Acker, S.A., Fluttert, M.F., De Kloet, E.R. , Blood pressure, heart rate, and behavioral responses to psychological "novelty" stress in freely moving rats, Psychophysiology, vol. 38, no. 3, pp. 490-499. DOI
Karssen, A.M., Meijer, O.C., van der Sandt, I.C., Lucassen, P.J., de Lange, E.C., de Boer, A.G., de Kloet, E.R. , Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain, Endocrinology, vol. 142, no. 6, pp. 2686-2694. DOI
Mulder, M., Blokland, A., van den Berg, D.J., Schulten, H., Bakker, A.H., Terwel, D., Honig, W., de Kloet, E.R., Havekes, L.M., Steinbusch, H.W., de Lange, E.C. , Apolipoprotein E protects against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging, Lab Invest, vol. 81, no. 7, pp. 953-60. DOI
Lucassen, P.J., Vollmann-Honsdorf, G.K., Gleisberg, M., Czeh, B., De Kloet, E.R., Fuchs, E. , Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew, Eur J Neurosci, vol. 14, no. 1, pp. 161-166. DOI
Workel, J.O., Oitzl, M.S., Fluttert, M.F., Lesscher, H., Karssen, A.M., de Kloet, E.R. , Differential and age-dependent effects of maternal deprivation on the hypothalamic-pituitary-adrenal axis of brown norway rats from youth to senescence, J Neuroendocrinol, vol. 13, no. 7, pp. 569-80. DOI
Lucassen, P.J., Muller, M.B., Holsboer, F., Bauer, J., Holtrop, A., Wouda, J., Hoogendijk, W.J., De Kloet, E.R., Swaab, D.F. , Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure, Am J Pathol, vol. 158, no. 2, pp. 453-68. DOI
Vreugdenhil, E., de Kloet, E.R., Schaaf, M.J., Datson, N.A. , Genetic dissection of corticosterone receptor function in the rat hippocampus, Eur Neuropsychopharmacol, vol. 11, no. 6, pp. 423-30. DOI
Sibug, R.M., Oitzl, M.S., Workel, J.O., de Kloet, E.R. , Maternal deprivation increases 5-HT(1A) receptor expression in the CA1 and CA3 areas of senescent Brown Norway rats, Brain Res, vol. 912, no. 1, pp. 95-8. DOI
Datson, N.A., van der Perk, J., de Kloet, E.R., Vreugdenhil, E. , Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression, Eur J Neurosci, vol. 14, no. 4, pp. 675-689. DOI
Grootendorst, J. , Stress effects on cognitive performance of apolipoprotein E knockout mice: Implications for Alzheimer's disease, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 193.
Oitzl, M.S. , Animal models of (traumatic) early life events: vulnerability to stress and cognition in later life, De neurobiologische en klinische aspecten van emotie en geheugen na psychotrauma, pp. 17-32.
Hendriksen, H., Datson, N.A., Ghijsen, W.E., van Vliet, E.A., da Silva, F.H., Gorter, J.A., Vreugdenhil, E. , Altered hippocampal gene expression prior to the onset of spontaneous seizures in the rat post-status epilepticus model, Eur J Neurosci, vol. 14, no. 9, pp. 1475-1484. DOI
Kruk, M.R., Halasz, J., Haller, J. , A dynamic adrenocortical stress system is crucial for the expression of hypothalamic aggression, Aggressive Behavior, vol. 27, no. 3, pp. 160-160. DOI
de Rijk, R.H., Meijer, O.C., De Kloet, E.R. , Brain corticosteroid receptors: targets for treatment of depression, Physical Consequences of Depression, Petersfield, UK, Wrightson Biomedical Pub, pp. 23-52.
De Kloet, E.R. , Corticosteroiden, Farmacologie, Utrecht, Wetenschappelijke Uitgeverij Bunge, pp. 194-205.
Kruidering, M., Schouten, T., Evan, G. I, Vreugdenhil, E. , Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis, J Biol Chem, vol. 276, no. 42, pp. 38417-38425. DOI
Meyer, U., Van Kampen, M., Isovich, E., Flugge, G., Fuchs, E. , Chronic psychosocial stress regulates the expression of both GR and MR mRNA in the hippocampal formation of tree shrews, Hippocampus, vol. 11, no. 3, pp. 329-336. DOI
Haller, J., van de Schraaf, J., Kruk, M.R. , Dynamics of steroids and territorial aggressive behavior, Aggressive Behavior, vol. 27, no. 3, pp. 159-160. DOI
Haller, J., van de Schraaf, J., Kruk, M.R. , Deviant forms of aggression in glucocorticoid hyporeactive rats: a model for 'pathological' aggression?, J Neuroendocrinol, vol. 13, no. 1, pp. 102-107. DOI
Kipling, ., Hoeijmakers, ., Kenemans, ., Naftolin, ., De Kloet, E.R., Gompel, . , DNA repair mechanisms - Discussion, Maturitas, vol. 38, no. 1, pp. 22-23. DOI
Datson, N.A., Vreugdenhil, E. , Expression Studies, Encyclopedia of Life Sciences: John Wiley & Sons, Ltd. DOI
Datson, N.A., van der Perk, J., de Kloet, E.R., Vreugdenhil, E. , Expression profile of 30,000 genes in rat hippocampus using SAGE, Hippocampus, vol. 11, no. 4, pp. 430-44. DOI
Hof, P.R., Mobbs, C.V. , Functional neurobiology of aging, , no. xxvii, 960, San Diego, Calif, Academic.
Lucassen, P.J., De Kloet, E.R. , Glucocorticoids and the Aging Brain: Cause or Consequence?, Functional Neurobiology of Aging, San Diego, Calif, Academic, pp. 883-905.
Vreugdenhil, E. , Glucocorticoid-mediated cell death in neuronal cell lines: an alternative model system to study neurodegenerative processes, Newsletter of the Netherlands Centre Alternatives to Animal Use (NCA), no. 11, Utrecht, Netherlands Centre Alternatives to Animal Use, pp. 4-6.
de Koning, J., Lambalk, C.B., Helmerhorst, F.M., Helder, M.N. , Is GnRH self-priming an obligatory feature of the reproductive cycle?, Hum Reprod, vol. 16, no. 2, pp. 209-214. DOI
Kreeft, A.J., Moen, C.J., Hofker, M.H., Frants, R.R., Vreugdenhil, E., Gijbels, M.J., Havekes, L.M., Datson, N.A. , Identification of differentially regulated genes in mildly hyperlipidemic ApoE3-Leiden mice by use of serial analysis of gene expression, Arterioscler Thromb Vasc Biol, vol. 21, no. 12, pp. 1984-1990. DOI
Visser, J., Lentjes, E., Haspels, I, Graffelman, W., Blauw, B., De Kloet, E.R., Nagelkerken, L. , Increased sensitivity to glucocorticoids in peripheral blood mononuclear cells of chronic fatigue syndrome patients, without evidence for altered density or affinity of glucocorticoid receptors, J Investig Med, vol. 49, no. 2, pp. 195-204. DOI
Rinne, T., van den Brink, W., Goekoop, J.G., de Rijk, R.H., De Kloet, E.R. , Neuroendocrine scars of severe childhood abuse in adult female borderline patients, Biol Psychiatry, vol. 49, no. 8, pp. 71S-71S. DOI
Haller, J., Fabich, K., Kruk, M.R. , Pulsating corticosterone secretion in male rats: Fast effects on aggressiveness, Aggressive Behavior, vol. 27, no. 3, pp. 221-222. DOI
Vis, P., Della Paschoa, O.E., Kruk, M.R., Martin, D., Mocaer, E., Danhof, M., Jochemsen, R. , Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-HT(1A) receptor agonist, using a behavioural model in rats, Eur J Pharmacol, vol. 414, no. 2-3, pp. 233-243. DOI
Grootendorst, J., de Kloet, E.R., Dalm, S., Oitzl, M.S. , Reversal of cognitive deficit of apolipoprotein E knockout mice after repeated exposure to a common environmental experience, Neuroscience, vol. 108, no. 2, pp. 237-47. DOI
De Kloet, E.R. , Stress in de Hersenen, Natuurkundige Voordrachten, vol. Nieuwe ree, Alphen a/d Rijn, Vis Offset, pp. 104-110.
Czeh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., Van Kampen, M., Bartolomucci, A., Fuchs, E. , Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine, PNAS, vol. 98, no. 22, pp. 12796-12801. DOI
Fuchs, E., Kruk, M.R. , Symposium: Glucocorticoids and aggression, Aggressive Behavior, vol. 27, no. 3, pp. 159-159. DOI
Gompel, ., Kipling, ., Ropers, ., Naftolin, ., De Kloet, E.R. , Telomeres, replicative senescence and human ageing - Discussion, Maturitas, vol. 38, no. 1, pp. 37-38. DOI
Ropers, ., Diczfalusy, ., De Kloet, E.R., Hulka, . , The demographic revolution and our common future - Discussion, Maturitas, vol. 38, no. 1, pp. 14-15. DOI
2000
de Kloet, E.R. , Stress in the brain, Eur J Pharmacol, vol. 405, no. 1-3, pp. 187-98. DOI
Sibug, R.M., Compaan, J.C., Meijer, O.C., Van der Gugten, J., Olivier, B., De Kloet, E.R. , Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus, Eur J Pharmacol, vol. 404, no. 1-2, pp. 111-9. DOI
Karst, H., Karten, Y.J., Reichardt, H.M., de Kloet, E.R., Schutz, G., Joels, M. , Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers, Nat Neurosci, vol. 3, no. 10, pp. 977-8. DOI
Oitzl, M.S., Workel, J.O., Fluttert, M.F., Frosch, F., De Kloet, E.R. , Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats, Eur J Neurosci, vol. 12, no. 10, pp. 3771-3780. DOI
Schaaf, M.J., De Kloet, E.R., Vreugdenhil, E. , Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation, Stress, vol. 3, no. 3, pp. 201-208. DOI
Grootendorst, J., Mulder, M., Haasdijk, E., de Kloet, E.R., Jaarsma, D. , Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion, Brain Res, vol. 868, no. 2, pp. 165-75. DOI
Meijer, O.C., Steenbergen, P.J., De Kloet, E.R. , Differential expression and regional distribution of steroid receptor coactivators SRC-1 and SRC-2 in brain and pituitary, Endocrinology, vol. 141, no. 6, pp. 2192-2199. DOI
Schaaf, M.J., Duurland, R., de Kloet, E.R., Vreugdenhil, E. , Circadian variation in BDNF mRNA expression in the rat hippocampus, Brain Res Mol Brain Res, vol. 75, no. 2, pp. 342-344. DOI
Dalm, S., Grootendorst, J., de Kloet, E.R., Oitzl, M.S. , Quantification of swim patterns in the Morris water maze, Behav Res Methods Instrum Comput, vol. 32, no. 1, pp. 134-139. DOI
de Kloet, E.R., Meijer, O.C., Vreugdenhil, E., Joels, M. , The Yin and Yang of nuclear receptors: symposium on nuclear receptors in brain, Oegstgeest, The Netherlands, 13-14 April 2000, Trends Endocrinol Metab, vol. 11, no. 6, pp. 245-8. DOI
de Kloet, E.R., Van Acker, S.A., Sibug, R.M., Oitzl, M.S., Meijer, O.C., Rahmouni, K., de Jong, W. , Brain mineralocorticoid receptors and centrally regulated functions, Kidney Int, vol. 57, no. 4, pp. 1329-36. DOI
Griep, E.N. , Fybromyalgia Syndrome. Neuroendocrine perspectives with clinical implications, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden, pp. 235.
Visser, J.T.J. , Cytokine Regulation by Glucocorticoids in the Chronic Fatigue Syndrome, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, LACDR, Dept. Medical Pharmacology, pp. 144.
Kruk, M.R. , Agressie: hypothalamus tussen hersenen en hormonen, Behandelingsstrategieën bij agressieve gedragsstoornissen, Houten/Diegem, Bohn Stafleu Van Loghem, pp. 1-13.
Bhatnagar, S., Viau, V., Chu, A., Soriano, L., Meijer, O.C., Dallman, M.F. , A cholecystokinin-mediated pathway to the paraventricular thalamus is recruited in chronically stressed rats and regulates hypothalamic-pituitary-adrenal function, J Neurosci, vol. 20, no. 14, pp. 5564-5573.
Fluttert, M.F., Dalm, S., Oitzl, M.S. , A refined method for sequential blood sampling by tail incision in rats, Lab Anim, vol. 34, no. 4, pp. 372-378. DOI
Visser, J.T., De Kloet, E.R., Nagelkerken, L. , Altered glucocorticoid regulation of the immune response in the chronic fatigue syndrome, Ann N Y Acad Sci, vol. 917, pp. 868-75. DOI
Meijer, O.C., De Kloet, E.R., McEwen, B.S. , Corticosteroid Receptors, Encyclopedia of Stress, vol. 1st, New York, Academic Press, pp. 557-569.
Lucassen, P.J., Vollmann-Honsdorf, G.K., Gleisberg, M., De Kloet, E.R., Fuchs, E. , Chronic psychosocial stress differentially influences the occurrence of apoptosis in the adult tree shrew hippocampus and cortex, Eur J Neurosci, vol. 12, pp. 303-303.
Van Kampen, M., Schmitt, U., Hiemke, C., Fuchs, E. , Diazepam has no beneficial effects on stress-induced behavioural and endocrine changes in male tree shrews, Pharmacol Biochem Behav, vol. 65, no. 3, pp. 539-546. DOI
Fink, G. , Encyclopedia of stress, , vol. 1st, no. 3 v, San Diego, Academic Press.
Gijsman, H.J., Verkes, R.J., Schouten-Verhagen, J.C., Schoemaker, R.C., Van Gerven, J.M., de Rijk, R.H., van Kempen, G.M. , Estimation of plasma serotonin using isopycnic centrifugation, Hum Psychopharmacol, vol. 15, no. 6, pp. 417-421. DOI
Oitzl, M.S., Grootendorst, J., Joels, M., Reichardt, H.M., Schutz, G., De Kloet, E.R. , Facilitation of spatial learning requires DNA-binding of the glucocorticoid receptor, Eur J Neurosci, vol. 12, pp. 170-170.
Lucassen, P.J., Labat-Moleur, F., Negoescu, A., van Lookeren Campagne, M. , Microwave-enhanced in situ end-labeling of apoptotic cells in tissue sections: pitfalls and possibilities, Antigen Retrieval Techniques, Natrick, MA, Eaton Publishing, pp. 71-91.
Bhargava, A., Meijer, O.C., Dallman, M.F., Pearce, D. , Plasma membrane calcium pump isoform 1 gene expression is repressed by corticosterone and stress in rat hippocampus, J Neurosci, vol. 20, no. 9, pp. 3129-3138.
Pearce, D., Verrey, F., Chen, S.Y., Mastroberardino, L., Meijer, O.C., Wang, J., Bhargava, A. , Role of SGK in mineralocorticoid-regulated sodium transport, Kidney Int., vol. 57, no. 4, pp. 1283-1289. DOI
Wissink, S., Meijer, O.C., Pearce, D., van der Burg, B., van der Saag, P.T. , Regulation of the rat serotonin-1A receptor gene by corticosteroids, J Biol Chem, vol. 275, no. 2, pp. 1321-1326. DOI
Karssen, A.M., De Kloet, E.R. , Synthetic Glucocorticoids, Encyclopedia of Stress, vol. 1st, New York, Academic Press, pp. 566-570.
Levine, S., Dent, G., De Kloet, E.R. , Stress Hyporesponsive Period, Encyclopedia of Stress, vol. 1st, New York, Academic Press, pp. 518-526.
Cabrera, R., Korte, S.M., Lentjes, E.G., Romijn, F., Schonbaum, E., De Nicola, A., De Kloet, E.R. , The amount of free corticosterone is increased during lipopolysaccharide-induced fever, Life Sci, vol. 66, no. 7, pp. 553-562. DOI
Haller, J., Millar, S., van de Schraaf, J., De Kloet, E.R., Kruk, M.R. , The active phase-related increase in corticosterone and aggression are linked, J Neuroendocrinol, vol. 12, no. 5, pp. 431-436. DOI
Meijer, O.C., Williamson, A., Dallman, M.F., Pearce, D. , Transcriptional repression of the 5-HT1A receptor promoter by corticosterone via mineralocorticoid receptors depends on the cellular context, J Neuroendocrinol, vol. 12, no. 3, pp. 245-254. DOI
Haller, J., Halasz, J., Mikics, E., Kruk, M.R., Makara, G.B. , Ultradian corticosterone rhythm and the propensity to behave aggressively in male rats, J Neuroendocrinol, vol. 12, no. 10, pp. 937-940. DOI
Simic, G., Seso-Simic, D., Lucassen, P.J., Islam, A., Krsnik, Z., Cviko, A., Jelasic, D., Barisic, N., Winblad, B., Kostovic, I, Kruslin, B. , Ultrastructural analysis and TUNEL demonstrate motor neuron apoptosis in Werdnig-Hoffmann disease, J Neuropathol Exp Neurol, vol. 59, no. 5, pp. 398-407.
1999
de Kloet, E.R., Oitzl, M.S., Joels, M. , Stress and cognition: are corticosteroids good or bad guys?, Trends Neurosci, vol. 22, no. 10, pp. 422-6. DOI
Datson, N.A., van der Perk-de Jong, J., van den Berg, M.P., de Kloet, E.R., Vreugdenhil, E. , MicroSAGE: a modified procedure for serial analysis of gene expression in limited amounts of tissue, Nucleic Acids Res, vol. 27, no. 5, pp. 1300-1307. DOI
Saravia, F.E., Grillo, C.A., Ferrini, M., Roig, P., Lima, A.E., de Kloet, E.R., De Nicola, A.F. , Changes of hypothalamic and plasma vasopressin in rats with deoxycorticosterone-acetate induced salt appetite, J Steroid Biochem Mol Biol, vol. 70, no. 1-3, pp. 47-57. DOI
Engels, B.M., Lucassen, P.J., de Kloet, E.R., Vreugdenhil, E. , Regional distribution of a novel calcium/calmodulin-dependent protein kinase mRNA in the rat brain, Brain Res, vol. 835, no. 2, pp. 365-8. DOI
Schaaf, M.J., Sibug, R.M., Duurland, R., Fluttert, M.F., Oitzl, M.S., De Kloet, E.R., Vreugdenhil, E. , Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training, Stress, vol. 3, no. 2, pp. 173-183. DOI
van Oers, H.J., de Kloet, E.R., Levine, S. , Persistent effects of maternal deprivation on HPA regulation can be reversed by feeding and stroking, but not by dexamethasone, J Neuroendocrinol, vol. 11, no. 8, pp. 581-8. DOI
Vreugdenhil, E., Datson, N.A., Engels, B.M., de Jong, J., van Koningsbruggen, S., Schaaf, M.J., de Kloet, E.R. , Kainate-elicited seizures induce mRNA encoding a CaMK-related peptide: a putative modulator of kinase activity in rat hippocampus, J Neurobiol, vol. 39, no. 1, pp. 41-50. DOI
Schaaf, M.J.M. , Corticosterone, BDNF and memory formation, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 119.
Kruk, M.R., Haller, J. , Corticosteroids and the escalation of violence in hypothalamic and territorial aggression in male rats, 5th IBRO world congress of neurosience: IBRO world congress, 11.-15.7.1999, pp. 36-36.
Workel, J.O. , Maternal deprivation: Implications for stress, cognition and aging, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, LACDR, Dept. Medical Pharmacology.
Lentjes, E.G.W.M. , Cortisol: bioavailability and receptors in stress-related disorders, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Kruk, M.R., Haller, J. , Acute Increases in Corticosterone and Attack Patterns in Rats, Behavioural Pharmacology, vol. 10, no. Suppl-1, pp. S54-S55.
Danik, M., Champagne, D.L., Petit-Turcotte, C., Beffert, U., Poirier, J. , Brain lipoprotein metabolism and its relation to neurodegenerative disease, Crit Rev Neurobiol, vol. 13, no. 4, pp. 357-407.
Chen, S.Y., Bhargava, A., Mastroberardino, L., Meijer, O.C., Wang, J., Buse, P., Firestone, G.L., Verrey, F., Pearce, D. , Epithelial sodium channel regulated by aldosterone-induced protein sgk, PNAS, vol. 96, no. 5, pp. 2514-2519. DOI
De Kloet, E.R. , Genetische verschillen in stressreacties, Ziekten maken en breken. Over farmacogenomie, Amsterdam, Boom/Belvédère, pp. 76-83.
Haller, J., Kruk, M.R. , Interactions Between Acute Corticosterone Activation and the Behavioral Effects of Noradrenergic and Serotonergic Agents, Behavioural Pharmacology, vol. 10, no. Suppl-1, pp. S43.
Karten, Y.J.G., Nair, S.M., van Essen, L., Sibug, R.M., Joels, M. , Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons, PNAS, vol. 96, no. 23, pp. 13456-13461. DOI
De Kloet, E.R. , Neurobiology of diseases in adaptation, Acta Neuropsychiatrica, vol. 11, no. 1, pp. 11-14.
Siegel, A., Roeling, T.A.P., Gregg, T.R., Kruk, M.R. , Neuropharmacology of brain-stimulation-evoked aggression, Neurosci Biobehav Rev, vol. 23, no. 3, pp. 359-389. DOI
van Dieten, J.A.M.J., Helder, M.N., van den Oever, C., de Koning, J. , Non-steroidal factors in bovine follicular fluid inhibit or facilitate the action of pulsatile administration of GnRH on LH release in the female rat, J Endocrinol, vol. 161, no. 2, pp. 237-243. DOI
Dallman, M.F., Akana, S.F., Bhatnagar, S., Bell, M.E., Choi, S., Chu, A., Horsley, C., Levin, N., Meijer, O.C., Soriano, L.R., Strack, A.M., Viau, V. , Starvation: early signals, sensors, and sequelae, Endocrinology, vol. 140, no. 9, pp. 4015-4023. DOI
1998
Mulder, M., Ravid, R., Swaab, D.F., de Kloet, E.R., Haasdijk, E.D., Julk, J., van der Boom, J.J., Havekes, L.M. , Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4, Alzheimer Dis Assoc Disord, vol. 12, no. 3, pp. 198-203.
Betancur, C., Cabrera, R., de Kloet, E.R., Pelaprat, D., Rostene, W. , Role of endogenous neurotensin in the behavioral and neuroendocrine effects of cocaine, Neuropsychopharmacology, vol. 19, no. 4, pp. 322-32. DOI
Schaaf, M.J., de Jong, J., de Kloet, E.R., Vreugdenhil, E. , Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone, Brain Res, vol. 813, no. 1, pp. 112-120. DOI
Beffert, U., Bertrand, P., Champagne, D.L., Gauthier, S., Poirier, J. , HSV-1 in brain and risk of Alzheimer's disease, Lancet, vol. 351, no. 9112, pp. 1330-1. DOI
Oitzl, M.S., Fluttert, M.F., de Kloet, E.R. , Acute blockade of hippocampal glucocorticoid receptors facilitates spatial learning in rats, Brain Res, vol. 797, no. 1, pp. 159-162. DOI
Meijer, O.C., Kortekaas, R., Oitzl, M.S., de Kloet, E.R. , Acute rise in corticosterone facilitates 5-HT(1A) receptor-mediated behavioural responses, Eur J Pharmacol, vol. 351, no. 1, pp. 7-14. DOI
Visser, J., van Boxel-Dezaire, A., Methorst, D., Brunt, T., de Kloet, E.R., Nagelkerken, L. , Differential regulation of interleukin-10 (IL-10) and IL-12 by glucocorticoids in vitro, Blood, vol. 91, no. 11, pp. 4255-4264.
De Kloet, E.R., Vreugdenhil, E., Oitzl, M.S., Joels, M. , Brain corticosteroid receptor balance in health and disease, Endocr Rev, vol. 19, no. 3, pp. 269-301. DOI
van Oers, H.J., de Kloet, E.R., Li, C., Levine, S. , The ontogeny of glucocorticoid negative feedback: influence of maternal deprivation, Endocrinology, vol. 139, no. 6, pp. 2838-2846. DOI
Sibug, R.M., Compaan, J.C., Meijer, O.C., Van der Gugten, J., Olivier, B., De Kloet, E.R. , Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels, Eur J Pharmacol, vol. 353, no. 2-3, pp. 207-14. DOI
Griep, E.N., Boersma, J.W., Lentjes, E.G., Prins, A.P., van der Korst, J.K., de Kloet, E.R. , Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain, J Rheumatol, vol. 25, no. 7, pp. 1374-1381.
Champagne, D.L., Beaulieu, J., Drolet, G. , CRFergic innervation of the paraventricular nucleus of the rat hypothalamus: a tract-tracing study, J Neuroendocrinol, vol. 10, no. 2, pp. 119-31. DOI
Visser, J., Blauw, B., Hinloopen, B., Brommer, E., de Kloet, E.R., Kluft, C., Nagelkerken, L. , CD4 T lymphocytes from patients with chronic fatigue syndrome have decreased interferon-gamma production and increased sensitivity to dexamethasone, J Infect Dis, vol. 177, no. 2, pp. 451-454. DOI
Gomez, F., De Kloet, E.R., Armario, A. , Glucocorticoid negative feedback on the HPA axis in five inbred rat strains, Am J Physiol Regul Integr Comp Physiol, vol. 274, no. 2, pp. R420-R427.
van Oers, H.J., de Kloet, E.R., Levine, S. , Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress, Brain Res Dev Brain Res, vol. 111, no. 2, pp. 245-252. DOI
van Oers, H.J., de Kloet, E.R., Whelan, T., Levine, S. , Maternal deprivation effect on the infant's neural stress markers is reversed by tactile stimulation and feeding but not by suppressing corticosterone, J Neurosci, vol. 18, no. 23, pp. 10171-10179.
Oitzl, M.S., Fluttert, M.F., Sutanto, W., de Kloet, E.R. , Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats, Eur J Neurosci, vol. 10, no. 12, pp. 3759-3766. DOI
Grillo, C.A., Saravia, F., Ferrini, M., Piroli, G., Roig, P., Garcia, S. I, de Kloet, E.R., De Nicola, A.F. , Increased expression of magnocellular vasopressin mRNA in rats with deoxycorticosterone-acetate induced salt appetite, Neuroendocrinology, vol. 68, no. 2, pp. 105-115. DOI
Meijer, O.C., de Lange, E.C., Breimer, D.D., de Boer, A.G., Workel, J.O., de Kloet, E.R. , Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice, Endocrinology, vol. 139, no. 4, pp. 1789-1793. DOI
De Nicola, A.F., Ferrini, M., Gonzalez, S.L., Gonzalez Deniselle, M.C., Grillo, C.A., Piroli, G., Saravia, F., de Kloet, E.R. , Regulation of gene expression by corticoid hormones in the brain and spinal cord, J Steroid Biochem Mol Biol, vol. 65, no. 1-6, pp. 253-272. DOI
Haller, J., Abraham, I, Zelena, D., Juhasz, G., Makara, G.B., Kruk, M.R. , Aggressive experience affects the sensitivity of neurons towards pharmacological treatment in the hypothalamic attack area, Behavioural Pharmacology, vol. 9, no. 5-6, pp. 469-475.
Haller, J., Halasz, J., Makara, G.B., Kruk, M.R. , Acute effects of glucocorticoids: behavioral and pharmacological perspectives, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 337-344. DOI
Ohl, F., Oitzl, M.S., Fuchs, E. , Assessing cognitive functions in tree shrews: visuo-spatial and spatial learning in the home cage, J Neurosci Methods, vol. 81, no. 1-2, pp. 35-40. DOI
Van Kampen, M., Fuchs, E. , Age-related levels of urinary free cortisol in the tree shrew, Neurobiol Aging, vol. 19, no. 4, pp. 363-366. DOI
Kruk, M.R. , Behavioral measurement in perspective? Reply, Trends Neurosci, vol. 21, no. 1, pp. 21-21. DOI
Vreugdenhil, E., de Kloet, E.R. , Corticosteroid hormones and neuronal vulnerability: Towards identification of candidate vulnerability genes, Prog Brain Res, vol. 117: Elsevier, pp. 9-22. DOI
Haller, J., Makara, G.B., Kruk, M.R. , Catecholaminergic involvement in the control of aggression: hormones, the peripheral sympathetic, and central noradrenergic systems, Neurosci Biobehav Rev, vol. 22, no. 1, pp. 85-97. DOI
Joels, M., Vreugdenhil, E. , Corticosteroids in the brain. Cellular and molecular actions, Mol Neurobiol, vol. 17, no. 1-3, pp. 87-108. DOI
Smits, H.H., Grunberg, K., de Rijk, R.H., Sterk, P.J., Hiemstra, P.S. , Cytokine release and its modulation by dexamethasone in whole blood following exercise, Clin Exp Immunol, vol. 111, no. 2, pp. 463-468. DOI
Laban, O., de Rijk, R.H., Sternberg, E.M. , Differential corticosteroid sensitivity of pro- and anti-inflammatory cytokines, FASEB Journal, vol. 12, no. 5, pp. A1052-A1052.
Vreugdenhil, E., de Jong, J., De Kloet, E.R., Datson, N.A. , Differential display, serial analysis of gem expression and corticosteroid actions in brain, Eur J Neurosci, vol. 10, pp. 265-265.
Della Paschoa, O.E., Kruk, M.R., Voskuyl, R.A., Danhof, M. , Effects of repeated seizure induction on seizure activity, post-ictal and interictal behavior, Brain Res, vol. 814, no. 1-2, pp. 199-208. DOI
Rodgers, J., Haller, J., Krsiak, M., Kruk, M.R. , Editorial, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 141-141. DOI
van Kesteren, R.E., Fainzilber, M., Hauser, G., van Minnen, J., Vreugdenhil, E., Smit, A.B., Ibanez, C.F., Geraerts, W.P., Bulloch, A.G. , Early evolutionary origin of the neurotrophin receptor family, EMBO J, vol. 17, no. 9, pp. 2534-2542. DOI
Rostene, W., Nicot, A., Scarceriaux, V., De Kloet, E.R., P‚laprat, D., B‚rod, A. , Interaction between glucocorticoids and neurotensin in normal and stress responses, New Frontiers in Stress Research; Modulation of Brain Function, Amsterdam, Harwood Academic Publishers, pp. 83-94.
Muler, M., van der Boom, H., Haasdijk, E.D., Dalm, S., De Kloet, E.R., Havekes, L.M., Holstege, J.C., Jaarsma, D. , Increased apolipoprotein E expression in a transgenic mouse model for amyotrophic lateral sclerosis, Eur J Neurosci, vol. 10, pp. 374-374.
Haller, J., Millar, S., Kruk, M.R. , Mineralocorticoid receptor blockade inhibits aggressive behaviour in male rats, Stress, vol. 2, no. 3, pp. 201-207. DOI
Tensen, C.P., Cox, K.J., Burke, J.F., Leurs, R., van der Schors, R.C., Geraerts, W.P., Vreugdenhil, E., Heerikhuizen, H. , Molecular cloning and characterization of an invertebrate homologue of a neuropeptide Y receptor, Eur J Neurosci, vol. 10, no. 11, pp. 3409-3416. DOI
van Oers, H.J. , Maternal Deprivation: Implications for the ontogeny of the neural stress circuitry, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, LACDR, Dept. Medical Pharmacology.
Levy, A., Grauer, E., Ben-Nathan, B., De Kloet, E.R. , New frontiers in stress research: modulation of brain function, , no. xix, 299 p, Australia, Harwood Academic.
Della Paschoa, O.E., Kruk, M.R., Danhof, M. , Phamacokinetic-pharmacodynamic modelling of behavioural responses, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 229-236. DOI
Della Paschoa, O.E., Kruk, M.R., Hamstra, R., Voskuyl, R.A., Danhof, M. , Pharmacodynamic interaction between phenytoin and sodium valproate changes seizure thresholds and pattern, Br J Pharmacol, vol. 125, no. 5, pp. 997-1004. DOI
Grootendorst, J., Dalm, S., De Kloet, E.R., Oitzl, M.S. , Spatial learning of apolipoprotein E knockout mice in a water maze: Influence of repeated exposure to rats, Brain Res, vol. 809, no. 1, pp. A29-A29.
Kruk, M.R., Westphal, K.G., Van Erp, A.M.M., van Asperen, J., Cave, B.J., Slater, E., de Koning, J., Haller, J. , The hypothalamus: cross-roads of endocrine and behavioural regulation in grooming and aggression, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 163-177. DOI
Tensen, C.P., Cox, K.J., Smit, A.B., van der Schors, R.C., Meyerhof, W., Richter, D., Planta, R.J., Hermann, P.M., van Minnen, J., Geraerts, W.P., Knol, J.C., Burke, J.F., Vreugdenhil, E., van Heerikhuizen, H. , The lymnaea cardioexcitatory peptide (LyCEP) receptor: a G-protein-coupled receptor for a novel member of the RFamide neuropeptide family, J Neurosci, vol. 18, no. 23, pp. 9812-9821.
1997
De Kloet, E.R. , Why Dexamethasone Poorly Penetrates in Brain, Stress, vol. 2, no. 1, pp. 13-20. DOI
Karst, H., de Kloet, E.R., Joels, M. , Effect of ORG 34116, a corticosteroid receptor antagonist, on hippocampal Ca2+ currents, Eur J Pharmacol, vol. 339, no. 1, pp. 17-26. DOI
Workel, J.O., Oitzl, M.S., Ledeboer, A., De Kloet, E.R. , The Brown Norway rat displays enhanced stress-induced ACTH reactivity at day 18 after 24-h maternal deprivation at day 3, Brain Res Dev Brain Res, vol. 103, no. 2, pp. 199-203. DOI
Karst, H., Bosma, A., Hendriksen, E., Kamphuis, W., de Kloet, E.R., Joels, M. , Effect of adrenalectomy in kindled rats, Neuroendocrinology, vol. 66, no. 5, pp. 348-359. DOI
van Haarst, A.D., Oitzl, M.S., de Kloet, E.R. , Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus, Neurochem Res, vol. 22, no. 11, pp. 1323-1328. DOI
Lentjes, E.G., Griep, E.N., Boersma, J.W., Romijn, F.P., de Kloet, E.R. , Glucocorticoid receptors, fibromyalgia and low back pain, Psychoneuroendocrinology, vol. 22, no. 8, pp. 603-614. DOI
Oitzl, M.S., de Kloet, E.R., Joels, M., Schmid, W., Cole, T.J. , Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption, Eur J Neurosci, vol. 9, no. 11, pp. 2284-2296. DOI
Bhatnagar, M., Cintra, A., Chadi, G., Lindberg, J., Oitzl, M.S., De Kloet, E.R., Moller, A., Agnati, L.F., Fuxe, K. , Neurochemical changes in the hippocampus of the brown Norway rat during aging, Neurobiol Aging, vol. 18, no. 3, pp. 319-327. DOI
Schaaf, M.J., Hoetelmans, R.W., de Kloet, E.R., Vreugdenhil, E. , Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus, J Neurosci Res, vol. 48, no. 4, pp. 334-41. DOI
Sandrenan, N., Sioufi, A., Godbillon, J., Netter, C., Donker, M., van Valkenburg, C.F. , Determination of artemether and its metabolite, dihydroartemisinin, in plasma by high-performance liquid chromatography and electrochemical detection in the reductive mode, J Chromatogr B, vol. 691, no. 1, pp. 145-153. DOI
Oitzl, M.S., Mulder, M., Lucassen, P.J., Havekes, L.M., Grootendorst, J., de Kloet, E.R. , Severe learning deficits in apolipoprotein E-knockout mice in a water maze task, Brain Res, vol. 752, no. 1-2, pp. 189-196. DOI
Meijer, O.C., Cole, T.J., Schmid, W., Schutz, G., Joels, M., De Kloet, E.R. , Regulation of hippocampal 5-HT1A receptor mRNA and binding in transgenic mice with a targeted disruption of the glucocorticoid receptor, Brain Res Mol Brain Res, vol. 46, no. 1-2, pp. 290-296. DOI
Krugers, H.J., Mulder, M., Korf, J., Havekes, L., de Kloet, E.R., Joels, M. , Altered synaptic plasticity in hippocampal CA1 area of apolipoprotein E deficient mice, Neuroreport, vol. 8, no. 11, pp. 2505-2510.
Szuran, T.F., van Haarst, A.D., de Kloet, E.R., Pliska, V. , Steroid receptors in the rat hippocampus: a note to the methodology of their binding assay, J Recept Signal Transduct Res, vol. 17, no. 1-3, pp. 337-354. DOI
De Kloet, E.R., Vreugdenhil, E., Oitzl, M.S., Joels, M. , Glucocorticoid feedback resistance, Trends Endocrinol Metab, vol. 8, no. 1, pp. 26-33. DOI
Ferrini, M.G., Grillo, C.A., Piroli, G., de Kloet, E.R., De Nicola, A.F. , Sex difference in glucocorticoid regulation of vasopressin mRNA in the paraventricular hypothalamic nucleus, Cell Mol Neurobiol, vol. 17, no. 6, pp. 671-686. DOI
van Oers, H.J., de Kloet, E.R., Levine, S. , Persistent, but Paradoxical, Effects on HPA Regulation of Infants Maternally Deprived at Different Ages, Stress, vol. 1, no. 4, pp. 249-262. DOI
Nicot, A., Rowe, W.B., De Kloet, E.R., Betancur, C., Jessop, D.S., Lightman, S.L., Quirion, R., Rostene, W., Berod, A. , Endogenous neurotensin regulates hypothalamic-pituitary-adrenal axis activity and peptidergic neurons in the rat hypothalamic paraventricular nucleus, J Neuroendocrinol, vol. 9, no. 4, pp. 263-269. DOI
Oitzl, M.S., van Haarst, A.D., de Kloet, E.R. , Behavioral and neuroendocrine responses controlled by the concerted action of central mineralocorticoid (MRS) and glucocorticoid receptors (GRS), Psychoneuroendocrinology, vol. 22, no. Suppl-1, pp. S87-S93. DOI
Cox, K.J., Tensen, C.P., van der Schors, R.C., Li, K.W., van Heerikhuizen, H., Vreugdenhil, E., Geraerts, W.P., Burke, J.F. , Cloning, characterization, and expression of a G-protein-coupled receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide, PSFHSWSamide, as its endogenous ligand, J Neurosci, vol. 17, no. 4, pp. 1197-1205.
de Rijk, R.H., Sternberg, E.M. , Corticosteroid resistance and disease, Ann Med, vol. 29, no. 1, pp. 79-82. DOI
Gerhardt, C.C., Lodder, H.C., Vincent, M., Bakker, R.A., Planta, R.J., Vreugdenhil, E., Kits, K.S., van Heerikhuizen, H. , Cloning and expression of a complementary DNA encoding a molluscan octopamine receptor that couples to chloride channels in HEK293 cells, J Biol Chem, vol. 272, no. 10, pp. 6201-6207. DOI
Joels, M., Karten, Y., Hesen, W., de Kloet, E.R. , Corticosteroid effects on electrical properties of brain cells: temporal aspects and role of antiglucocorticoids, Psychoneuroendocrinology, vol. 22 Suppl 1, pp. S81-S86. DOI
De Kloet, E.R. , Early experience, genotype and vulnerability to depressive illness, De pathogenese van stoornissen in de affectregulatie; een psychobiologische integratie. Boerhaave course, pp. 53-59.
de Rijk, R.H., Michelson, D., Karp, B., Petrides, J., Galliven, E., Deuster, P., Paciotti, G., Gold, P.W., Sternberg, E.M. , Exercise and circadian rhythm-induced variations in plasma cortisol differentially regulate interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor-alpha (TNF alpha) production in humans: high sensitivity of TNF alpha and resistance of IL-6, J Clin Endocrinol Metab, vol. 82, no. 7, pp. 2182-2191. DOI
Zant, J.L., Mooij, A., Griep, E.N., Boersma, J.W., De Kloet, E.R. , Fibromyalgia in relation to the process of early attachment, Nederlands Tijdschrift voor Pijn en Pijnbestrijding (NTPP), vol. 17, no. 2, pp. 25-27.
de Rijk, R.H., Sternberg, E.M., De Kloet, E.R. , Glucocorticoid receptor function in health and disease, Current Opinion in Endocrinology & Diabetes, vol. 4, no. 3, pp. 185-193.
Wilckens, T., de Rijk, R.H. , Glucocorticoids and immune function: unknown dimensions and new frontiers, Immunol Today, vol. 18, no. 9, pp. 418-424. DOI
Gerhardt, C.C., Bakker, R.A., Piek, G.J., Planta, R.J., Vreugdenhil, E., Leysen, J.E., van Heerikhuizen, H. , Molecular cloning and pharmacological characterization of a molluscan octopamine receptor, Mol Pharmacol, vol. 51, no. 2, pp. 293-300.
Kruk, M.R. , Measuring behaviour into the twenty-first century, Trends Neurosci, vol. 20, no. 5, pp. 187-189. DOI
Smith, M.A., Kim, S.Y., van Oers, H.J., Levine, S. , Maternal deprivation and stress induce immediate early genes in the infant rat brain, Endocrinology, vol. 138, no. 11, pp. 4622-4628. DOI
Brus, L., Lambalk, C.B., de Koning, J., Helder, M.N., Janssens, R.M., Schoemaker, J. , Specific gonadotrophin-releasing hormone analogue binding predominantly in human luteinized follicular aspirates and not in human pre-ovulatory follicles, Hum Reprod, vol. 12, no. 4, pp. 769-773. DOI
De Kloet, E.R., Oitzl, M.S. , Special issue dedicated to Dr. Bruce S. McEwen - Preface, Neurochem Res, vol. 22, no. 11, pp. 1319-1320. DOI
Della Paschoa, O.E., Kruk, M.R., Hamstra, R., Voskuyl, R.A., Danhof, M. , Seizure patterns in kindling and cortical stimulation models of experimental epilepsy, Brain Res, vol. 770, no. 1-2, pp. 221-227. DOI
De Kloet, E.R. , Toekomstperspectieven in de behandeling van de ziekte van Alzheimer, Folia Pharmaceutica, vol. 9, pp. 21-31.
1996
Vreugdenhil, E., de Jong, J., Schaaf, M.J., Meijer, O.C., Busscher, J., Vuijst, C., de Kloet, E.R. , Molecular dissection of corticosteroid action in the rat hippocampus. Application of the differential display techniques, J Mol Neurosci, vol. 7, no. 2, pp. 135-146. DOI
De Kloet, E.R., Korte, S.M., Rots, N.Y., Kruk, M.R. , Stress hormones, genotype, and brain organization. Implications for aggression, Ann N Y Acad Sci, vol. 794, pp. 179-91. DOI
Korte, S.M., Meijer, O.C., de Kloet, E.R., Buwalda, B., Keijser, J., Sluyter, F., van Oortmerssen, G., Bohus, B. , Enhanced 5-HT1A receptor expression in forebrain regions of aggressive house mice, Brain Res, vol. 736, no. 1-2, pp. 338-343. DOI
Hesen, W., Karst, H., Meijer, O.C., Cole, T.J., Schmid, W., de Kloet, E.R., Schutz, G., Joels, M. , Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption, J Neurosci, vol. 16, no. 21, pp. 6766-6774.
Korte-Bouws, G.A., Korte, S.M., De Kloet, E.R., Bohus, B. , Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis, J Neuroendocrinol, vol. 8, no. 11, pp. 877-881. DOI
van Haarst, A.D., Oitzl, M.S., Workel, J.O., de Kloet, E.R. , Chronic brain glucocorticoid receptor blockade enhances the rise in circadian and stress-induced pituitary-adrenal activity, Endocrinology, vol. 137, no. 11, pp. 4935-4943. DOI
Rots, N.Y., Cools, A.R., Oitzl, M.S., de Jong, J., Sutanto, W., de Kloet, E.R. , Divergent prolactin and pituitary-adrenal activity in rats selectively bred for different dopamine responsiveness, Endocrinology, vol. 137, no. 5, pp. 1678-1686. DOI
Korte, S.M., Korte-Bouws, G.A., Koob, G.F., De Kloet, E.R., Bohus, B. , Mineralocorticoid and glucocorticoid receptor antagonists in animal models of anxiety, Pharmacol Biochem Behav, vol. 54, no. 1, pp. 261-267. DOI
de Kloet, E.R., Rots, N.Y., Cools, A.R. , Brain-corticosteroid hormone dialogue: slow and persistent, Cell Mol Neurobiol, vol. 16, no. 3, pp. 345-356. DOI
Vreugdenhil, E., de Jong, J., Busscher, J.S., de Kloet, E.R. , Kainic acid-induced gene expression in the rat hippocampus is severely affected by adrenalectomy, Neurosci Lett, vol. 212, no. 2, pp. 75-78. DOI
Hornsby, C.D., Grootendorst, J., de Kloet, E.R. , Dexamethasone Does Not Prevent Seven-Day ADX-Induced Apoptosis in the Dentate Gyrus of the Rat Hippocampus, Stress, vol. 1, no. 1, pp. 51-64. DOI
Rots, N.Y., de Jong, J., Workel, J.O., Levine, S., Cools, A.R., De Kloet, E.R. , Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine, J Neuroendocrinol, vol. 8, no. 7, pp. 501-506. DOI
Korte, S.M., Buwalda, B., De Kloet, E.R., Bohus, B. , Adrenaline release by the 5-HT1A receptor agonist 8-OH-DPAT is partly responsible for pituitary activation, Eur J Pharmacol, vol. 309, no. 3, pp. 281-286. DOI
van Haarst, A.D., Welberg, L.A., Sutanto, W., Oitzl, M.S., de Kloet, E.R. , 11 beta-Hydroxysteroid dehydrogenase activity in the hippocampus: implications for in vivo corticosterone receptor binding and cell nuclear retention, J Neuroendocrinol, vol. 8, no. 8, pp. 595-600. DOI
Rots, N.Y., Workel, J., Oitzl, M.S., Berod, A., Rostene, W., Cools, A.R., De Kloet, E.R. , Development of divergence in dopamine responsiveness in genetically selected rat lines is preceded by changes in pituitary-adrenal activity, Brain Res Dev Brain Res, vol. 92, no. 2, pp. 164-171. DOI
Sutanto, W., Rosenfeld, P., de Kloet, E.R., Levine, S. , Long-term effects of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors, Brain Res Dev Brain Res, vol. 92, no. 2, pp. 156-163. DOI
Korte, S.M., De Kloet, E.R., Buwalda, B., Bouman, S.D., Bohus, B. , Antisense to the glucocorticoid receptor in hippocampal dentate gyrus reduces immobility in forced swim test, Eur J Pharmacol, vol. 301, no. 1-3, pp. 19-25. DOI
Beaulieu, J., Champagne, D.L., Drolet, G. , Enkephalin innervation of the paraventricular nucleus of the hypothalamus: distribution of fibers and origins of input, J Chem Neuroanat, vol. 10, no. 2, pp. 79-92. DOI
van Steensel, B., van Binnendijk, E.P., Hornsby, C.D., van der Voort, H.T., Krozowski, Z.S., de Kloet, E.R., van Driel, R. , Partial colocalization of glucocorticoid and mineralocorticoid receptors in discrete compartments in nuclei of rat hippocampus neurons, J Cell Sci, vol. 109, no. 4, pp. 787-792.
Meijer, O.C. , Corticosterone and Hippocampal 5-HT 1A Receptors: Functional implications of central corticosteroid receptor diversity, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
De Kloet, E.R. , Corticosteroiden, Farmacologie, Utrecht, Wetenschappelijke Uitgeverij Bunge, pp. 175-184.
Datson, N.A., Semina, E., van Staalduinen, A.A., Dauwerse, H.G., Meershoek, E.J., Heus, J.J., Frants, R.R., den Dunnen, J.T., Murray, J.C., van Ommen, G.J. , Closing in on the Rieger syndrome gene on 4q25: mapping translocation breakpoints within a 50-kb region, Am J Hum Genet, vol. 59, no. 6, pp. 1297-1305.
De Kloet, E.R., Joels, M. , Corticosteroid hormones in neuroprotection and brain damage, Current Opinion in Endocrinology & Diabetes, vol. 3, no. 2, pp. 184-192.
de Rijk, R.H., Petrides, J., Deuster, P., Gold, P.W., Sternberg, E.M. , Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans, J Clin Endocrinol Metab, vol. 81, no. 1, pp. 228-235. DOI
Semina, E.V., Reiter, R., Leysens, N.J., Alward, W.L., Small, K.W., Datson, N.A., Siegel-Bartelt, J., Bierke-Nelson, D., Bitoun, P., Zabel, B.U., Carey, J.C., Murray, J.C. , Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome, Nat Genet, vol. 14, no. 4, pp. 392-399. DOI
van Kesteren, R.E., Tensen, C.P., Smit, A.B., van Minnen, J., Kolakowski, L.F., Meyerhof, W., Richter, D., van Heerikhuizen, H., Vreugdenhil, E., Geraerts, W.P. , Co-evolution of ligand-receptor pairs in the vasopressin/oxytocin superfamily of bioactive peptides, J Biol Chem, vol. 271, no. 7, pp. 3619-3626. DOI
de Rijk, R.H., Michelson, D., Gold, P.W., Sternberg, E.M. , Different sensitivity of IL-1 beta, IL-6 and TNF alpha to corticosteroids as measured ex vivo, FASEB Journal, vol. 10, no. 6, pp. 312-312.
Semina, E.V., Datson, N.A., Leysens, N.J., Zabel, B.U., Carey, J.C., Bell, G. I, Bitoun, P., Lindgren, C., Stevenson, T., Frants, R.R., van Ommen, G.J., Murray, J.C. , Exclusion of epidermal growth factor and high-resolution physical mapping across the Rieger syndrome locus, Am J Hum Genet, vol. 59, no. 6, pp. 1288-1296.
De Kloet, E.R. , Functional implications of brain corticosteroid receptor diversity, Medicina-Buenos Aires, vol. 56, no. 5, pp. 633-633.
Gerhardt, C.C., Leysen, J.E., Planta, R.J., Vreugdenhil, E., van Heerikhuizen, H. , Functional characterisation of a 5-HT2 receptor cDNA cloned from Lymnaea stagnalis, Eur J Pharmacol, vol. 311, no. 2-3, pp. 249-258. DOI
Sibug, R.M., Kuppers, E., Beyer, C., Maxson, S.C., Pilgrim, C., Reisert, I , Genotype-dependent sex differentiation of dopaminergic neurons in primary cultures of embryonic mouse brain, Brain Res Dev Brain Res, vol. 93, no. 1-2, pp. 136-142. DOI
De Kloet, E.R. , Hormones, stress and cognitive failure, Medicina-Buenos Aires, vol. 56, no. 5, pp. 629-629.
Molewijk, H.E., Hartog, K., van der Poel, A.M., Mos, J., Olivier, B. , Reduction of guinea pig pup isolation calls by anxiolytic and antidepressant drugs, Psychopharmacology, vol. 128, no. 1, pp. 31-38. DOI
Vazquez, D.M., van Oers, H.J., Levine, S., Akil, H. , Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat, Brain Res, vol. 731, no. 1-2, pp. 79-90. DOI
Datson, N.A., van de Vosse, E., Dauwerse, H.G., Bout, M., van Ommen, G.J., den Dunnen, J.T. , Scanning for genes in large genomic regions: cosmid-based exon trapping of multiple exons in a single product, Nucleic Acids Res, vol. 24, no. 6, pp. 1105-1111. DOI
De Kloet, E.R. , Toekomstperspectieven in de behandeling van de Ziekte van Alzheimer, De Ziekte van Alzheimer; Boerhaave course, pp. 101-115.
1995
van Steensel, B., Brink, M., van der Meulen, K., van Binnendijk, E.P., Wansink, D.G., de Jong, L., de Kloet, E.R., van Driel, R. , Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus, J Cell Sci, vol. 108, no. 9, pp. 3003-3011.
Van de Vosse, E., Van der Bent, P., Datson, N.A., Schuurman, E.J.M., Bergen, A.A.B., Van Ommen, G.J.B., Den Dunnen, J.T. , Construction of a transcription map in the region of the retinoschisis disease gene, Am J Hum Genet, vol. 57, no. 4, pp. 1988-1988.
Datson, N.A., Van Staalduinen, A.A., Semina, E., Meershoek, E.M., Heus, J.J., Hofker, M.H., Murray, J., Frants, R.R., Van Ommen, G.J.B., Den Dunnen, J.T. , Mapping translocation breakpoints in Rieger syndrome within a 200 KB region, Am J Hum Genet, vol. 57, no. 4, pp. 1496-1496.
de Kloet, E.R. , Steroids, stability and stress, Front Neuroendocrinol, vol. 16, no. 4, pp. 416-425. DOI
Den Dunnen, J.T., Datson, N.A., Van de Vosse, E., Dauwerse, J.G., Van Ommen, G.J.B. , Scanning for genes with a cosmid-based exon trap vector, Am J Hum Genet, vol. 57, no. 4, pp. 149-149.
Sutanto, W., de Kloet, E.R. , Corticosteroid receptor antagonists: a current perspective, Pharm World Sci, vol. 17, no. 2, pp. 31-41. DOI
Van Eekelen, J.A., Oitzl, M.S., De Kloet, E.R. , Adrenocortical hyporesponsiveness and glucocorticoid feedback resistance in old male brown Norway rats, J Gerontol A Biol Sci Med Sci, vol. 50A, no. 2, pp. B83-B89. DOI
Joels, M., Hesen, W., de Kloet, E.R. , Long-term control of neuronal excitability by corticosteroid hormones, J Steroid Biochem Mol Biol, vol. 53, no. 1-6, pp. 315-323. DOI
Korte, S.M., Buwalda, B., Meijer, O.C., De Kloet, E.R., Bohus, B. , Socially defeated male rats display a blunted adrenocortical response to a low dose of 8-OH-DPAT, Eur J Pharmacol, vol. 272, no. 1, pp. 45-50. DOI
Rots, N.Y., Cools, A.R., de Jong, J., De Kloet, E.R. , Corticosteroid feedback resistance in rats genetically selected for increased dopamine responsiveness, J Neuroendocrinol, vol. 7, no. 2, pp. 153-161. DOI
Vallee, S.M., Grillo, C.A., Gonzalez, S., Cosen-Binker, L., de Kloet, E.R., McEwen, B.S., De Nicola, A.F. , Further studies in deoxycorticosterone acetate treated rats: brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake, Neuroendocrinology, vol. 61, no. 2, pp. 117-124. DOI
Carey, M.P., Deterd, C.H., de Koning, J., Helmerhorst, F., de Kloet, E.R. , The influence of ovarian steroids on hypothalamic-pituitary-adrenal regulation in the female rat, J Endocrinol, vol. 144, no. 2, pp. 311-321. DOI
Cruts, M., Backhovens, H., Wang, S.Y., Van Gassen, G., Theuns, J., De Jonghe, C., Wehnert, A., De Voecht, J., De Winter, G., Cras, P., Bruyland, M., Datson, N.A., Weissenbach, J., Den Dunnen, J.T., Martin, J.J., Hendriks, L., Van Broeckhoven, C. , Molecular-genetic analysis of familial early-onset Alzheimers-disease linked to chromosome 14Q24.3, Human Molecular Genetics, vol. 4, no. 12, pp. 2363-2371. DOI
Rots, N.Y. , Dopamine and Stress, studies with genetically selected rat lines, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden.
Wiegers, G.J. , Glucocorticoid hormone action in the immune system revisited, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden, pp. 186.
Tio, S. , GnSIF/AF: purification and physiological aspects, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden, pp. 176 p..
Bressers, W.M., Kruk, M.R., Van Erp, A.M.M., Willekens-Bramer, D.C., Haccou, P., Meelis, E. , A time-structured analysis of hypothalamically induced increases in self-grooming and activity in the rat, Behav Neurosci, vol. 109, no. 6, pp. 1158-1171. DOI
Knol, J.C., van der Slik, A.R., van Kesteren, E.R., Planta, R.J., van Heerikhuizen, H., Vreugdenhil, E. , A novel G protein alpha subunit containing atypical guanine nucleotide-binding domains is differentially expressed in a molluscan nervous system, J Biol Chem, vol. 270, no. 32, pp. 18804-18808. DOI
Korte, S.M., de Boer, S.F., de Kloet, E.R., Bohus, B. , Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze, Psychoneuroendocrinology, vol. 20, no. 4, pp. 385-394. DOI
Suchecki, D., Nelson, D.Y., van Oers, H.J., Levine, S. , Activation and inhibition of the hypothalamic-pituitary-adrenal axis of the neonatal rat: effects of maternal deprivation, Psychoneuroendocrinology, vol. 20, no. 2, pp. 169-182. DOI
van Kesteren, R.E., Tensen, C.P., Smit, A.B., van Minnen, J., van Soest, P.F., Kits, K.S., Meyerhof, W., Richter, D., van Heerikhuizen, H., Vreugdenhil, E. , A novel G protein-coupled receptor mediating both vasopressin- and oxytocin-like functions of Lys-conopressin in Lymnaea stagnalis, Neuron, vol. 15, no. 4, pp. 897-908. DOI
Joels, M., De Kloet, E.R. , Corticosteroid Hormones - Endocrine Messengers in the Brain, News Physiol Sci, vol. 10, no. 2, pp. 71-76.
Knol, J.C., Ramnatsingh, S., van Kesteren, E.R., van Minnen, J., Planta, R.J., van Heerikhuizen, H., Vreugdenhil, E. , Cloning of a molluscan G protein alpha subunit of the Gq class which is expressed differentially in identified neurons, Eur J Biochem, vol. 230, no. 1, pp. 193-199. DOI
Molewijk, H.E., van der Poel, A.M., Mos, J., Van der Heyden, J.A.M., Olivier, B. , Conditioned ultrasonic distress vocalizations in adult male rats as a behavioural paradigm for screening anti-panic drugs, Psychopharmacology, vol. 117, no. 1, pp. 32-40. DOI
Roovers, E., Vincent, M.E., van Kesteren, E.R., Geraerts, W.P., Planta, R.J., Vreugdenhil, E., van Heerikhuizen, H. , Characterization of a putative molluscan insulin-related peptide receptor, Gene, vol. 162, no. 2, pp. 181-188. DOI
Noach, E.L. , Ethical assessment of biomedical experiments in The Netherlands, Verh K Acad Geneeskd Belg, vol. 57, no. 3, pp. 158-179; discussion 179-182.
Powis, D.A., Bunn, S.J. , Neurotransmitter release and its modulation biochemical mechanisms, physiological function, and clinical relevance, , no. xviii, 356, Cambridge, Cambridge University Press, pp. 143-159.
Van Erp, A.M.M., Kruk, M.R., Veening, J.G., Roeling, T.A.P., Meelis, W. , Neuronal substrate of electrically induced grooming in the PVH of the rat: involvement of oxytocinergic systems?, Physiol Behav, vol. 57, no. 5, pp. 881-885. DOI
Van Erp, A.M.M., Kruk, M.R., Willekens-Bramer, D.C., Fermont, P.C., Nijsen, M.J. , PVH lesions do not inhibit stressor-induced grooming in the rat, Physiol Behav, vol. 57, no. 5, pp. 887-892. DOI
Drolet, G., Beaulieu, J., Mansi, J.A., Champagne, D.L., Laforest, S. , Relationship between exposure to stress and development of hypertension, Ann Endocrinol (Paris), vol. 56, no. 3, pp. 187-191.
De Kloet, E.R., Wiegant, V.M. , Stress and Neuropathology, Boerhaave cursus, no. viii, 153 , Leiden, Boerhaave Commissie voor Postacademisch Onderwijs in de Geneeskunde, Rijksuniversiteit Leiden, pp. 7-22.
Rostene, W., Sarrieau, A., Nicot, A., Scarceriaux, V., Betancur, C., Gully, D., Meaney, M., Rowe, W., De Kloet, E.R., Pelaprat, D. , Steroid effects on brain functions: an example of the action of glucocorticoids on central dopaminergic and neurotensinergic systems, J Psychiatry Neurosci, vol. 20, no. 5, pp. 349-356.
van Steensel, B., Binnendijk, E., van der Meulen, K., Jenster, G., Damm, K., Hornsby, C.D., Wansink, D.G., De Kloet, E.R., vanDriel, R. , Steroid-Receptors, Transcription and Nuclear Architecture, J Cellular Biochemistry, pp. 141-141.
Visser, G.M., Krugers, H.J., Luurtsema, G., Van Waarde, A., Elsinga, P.H., De Kloet, E.R., Groen, M.B., Bohus, B., Go, K.G., Paans, A.M.J., Korf, J., Vaalburg, W. , Synthesis and Organ Distribution of [F-18]Fluoro-Org-6141 in the Rat - A Potential Glucocorticoid Receptor-Ligand for Positron Emission Tomography, Nuclear Medicine and Biology, vol. 22, no. 7, pp. 915-920. DOI
Bressers, W.M., Kruk, M.R., Van Erp, A.M.M., Willekens-Bramer, D.C., Haccou, P., Meelis, E. , Time structure of self-grooming in the rat: self-facilitation and effects of hypothalamic stimulation and neuropeptides, Behav Neurosci, vol. 109, no. 5, pp. 955-964. DOI
Molewijk, H.E., van der Poel, A.M., Olivier, B. , The ambivalent behaviour "stretched approach posture" in the rat as a paradigm to characterize anxiolytic drugs, Psychopharmacology, vol. 121, no. 1, pp. 81-90. DOI
1994
Sutanto, W., de Kloet, E.R. , The use of various animal models in the study of stress and stress-related phenomena, Lab Anim, vol. 28, no. 4, pp. 293-306. DOI
Meijer, O.C., Oitzl, M.S., de Kloet, E.R. , Adrenalectomy leads to a different responsiveness to 8-OH-DPAT in a water-maze learning task, Ann N Y Acad Sci, vol. 746, pp. 408-10. DOI
de Kloet, E.R., Rots, N.Y., van den Berg, D.T., Oitzl, M.S. , Brain mineralocorticoid receptor function, Ann N Y Acad Sci, vol. 746, pp. 8-20; discussion 20-1, 64-7. DOI
Hornsby, C.D., de Kloet, E.R. , Dexamethasone does not prevent apoptosis in the hippocampus of the rat, Ann N Y Acad Sci, vol. 746, pp. 470-2. DOI
Carey, M.P., de Kloet, E.R. , Interaction of progesterone with the hippocampal mineralocorticoid receptor, Ann N Y Acad Sci, vol. 746, pp. 434-7. DOI
Korte, S.M., Buwalda, B., de Kloet, E.R., Bohus, B. , Social defeat impairs plasma corticosterone response to the 5-HT1A agonist 8-OH-DPAT in the rat, Ann N Y Acad Sci, vol. 746, pp. 426-8. DOI
Cirulli, F., van Oers, H., De Kloet, E.R., Levine, S. , Differential influence of corticosterone and dexamethasone on schedule-induced polydipsia in adrenalectomized rats, Behav Brain Res, vol. 65, no. 1, pp. 33-9. DOI
Schobitz, B., De Kloet, E.R., Holsboer, F. , Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain, Prog Neurobiol, vol. 44, no. 4, pp. 397-432. DOI
Griep, E.N., Boersma, J.W., de Kloet, E.R. , Pituitary release of growth hormone and prolactin in the primary fibromyalgia syndrome, J Rheumatol, vol. 21, no. 11, pp. 2125-30.
Nicot, A., Berod, A., Gully, D., Rowe, W., Quirion, R., de Kloet, E.R., Rostene, W. , Blockade of neurotensin binding in the rat hypothalamus and of the central action of neurotensin on the hypothalamic-pituitary-adrenal axis with non-peptide receptor antagonists, Neuroendocrinology, vol. 59, no. 6, pp. 572-578. DOI
Joels, M., Hesen, W., Karst, H., de Kloet, E.R. , Steroids and electrical activity in the brain, J Steroid Biochem Mol Biol, vol. 49, no. 4-6, pp. 391-398. DOI