All journal publications (1904-2014)

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2012
Schnörr, S.J., Steenbergen, P.J., Richardson, M.K., Champagne, D.L. , Measuring thigmotaxis in larval zebrafish, Behav Brain Res, vol. 228, no. 2, pp. 367-374. DOI
Converse, A.K., Aubert, Y., Farhoud, M., Weichert, J.P., Rowland, I.J., Ingrisano, N.M., Allers, K.A., Sommer, B., Abbott, D.H. , Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets, Neuroimage, vol. 60, no. 1, pp. 447-55. DOI
2010
Sarabdjitsingh, R.A., Isenia, S., Polman, J.A., Mijalkovic, J., Lachize, S.B., Datson, N.A., de Kloet, E.R., Meijer, O.C. , Disrupted corticosterone pulsatile patterns attenuate responsiveness to glucocorticoid signaling in rat brain, Endocrinology, vol. 151, no. 3, pp. 1177-1186. DOI
Dijkmans, T.F., van Hooijdonk, L.W., Fitzsimons, C.P., Vreugdenhil, E. , The doublecortin gene family and disorders of neuronal structure, Cent Nerv Syst Agents Med Chem, vol. 10, no. 1, pp. 32-46.
de Kloet, E.R. , From vasotocin to stress and cognition, Eur J Pharmacol, vol. 626, no. 1, pp. 18-26. DOI
van Leeuwen, N., Kumsta, R., Entringer, S., de Kloet, E.R., Zitman, F.G., De Rijk, R.H., Wust, S. , Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone, Psychoneuroendocrinology, vol. 35, no. 3, pp. 339-349. DOI
Bohnke, R., Bertsch, K., Kruk, M.R., Richter, S., Naumann, E. , Exogenous cortisol enhances aggressive behavior in females, but not in males, Psychoneuroendocrinology, vol. 35, no. 7, pp. 1034-1044. DOI
Schwabe, L., Wolf, O.T., Oitzl, M.S. , Memory formation under stress: quantity and quality, Neurosci Biobehav Rev, vol. 34, no. 4, pp. 584-591. DOI
Van Batenburg, M.F., Li, H., Polman, J.A., Lachize, S.B., Datson, N.A., Bussemaker, H.J., Meijer, O.C. , Paired hormone response elements predict caveolin-1 as a glucocorticoid target gene, PLoS One, vol. 5, no. 1, pp. 1-9. DOI
Sarabdjitsingh, R.A., Spiga, F., Oitzl, M.S., Kershaw, Y., Meijer, O.C., Lightman, S.L., De Kloet, E.R. , Recovery from disrupted ultradian glucocorticoid rhythmicity reveals a dissociation between hormonal and behavioral stress responsiveness, J Neuroendocrinol, vol. 22, no. 8, pp. 862-871. DOI
Bohnke, R., Bertsch, K., Kruk, M.R., Naumann, E. , The relationship between basal and acute HPA axis activity and aggressive behavior in adults, J Neural Transm, vol. 117, no. 5, pp. 629-637. DOI
Murphy, K.J., Ter Horst, J.P., Cassidy, A.W., DeSouza, I.E., Morgunova, M., Li, C., Connole, L.M., O'Sullivan, N.C., Loscher, J.S., Brady, A.T., Rombach, N., Connellan, J., McGettigan, P.A., Scully, D., Fedriani, R., Lukasz, B., Moran, M.P., McCabe, O.M., Wantuch, C.M., Hughes, Z.A., Mulvany, S.K., Higgins, D.G., Pangalos, M.N., Marquis, K.L., O'Connor, W.T., Ring, R.H., von Schack, D., Regan, C.M. , Temporal dysregulation of cortical gene expression in the isolation reared Wistar rat, J Neurochem, vol. 113, no. 3, pp. 601-614. DOI
2009
Richardson, M.K., Gobes, S.M., van Leeuwen, A.C., Polman, J.A., Pieau, C., Sanchez-Villagra, M.R. , Heterochrony in limb evolution: developmental mechanisms and natural selection, J Exp Zool B Mol Dev Evol, vol. 312, no. 6, pp. 639-664. DOI
de Kloet, E.R., Fitzsimons, C.P., Datson, N.A., Meijer, O.C., Vreugdenhil, E. , Glucocorticoid signaling and stress-related limbic susceptibility pathway: about receptors, transcription machinery and microRNA, Brain Res, vol. 1293, pp. 129-141. DOI
van Gemert, N.G., Carvalho, D.M., Karst, H., van der Laan, S., Zhang, M., Meijer, O.C., Hell, J.W., Joels, M. , Dissociation between rat hippocampal CA1 and dentate gyrus cells in their response to corticosterone: effects on calcium channel protein and current, Endocrinology, vol. 150, no. 10, pp. 4615-4624. DOI
Lachize, S.B., Apostolakis, E.M., van der Laan, S., Tijssen, A.M., Xu, J., de Kloet, E.R., Meijer, O.C. , Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids, PNAS, vol. 106, no. 19, pp. 8038-8042. DOI
Vreugdenhil, E., Verissimo, C.S., Mariman, R., Kamphorst, J.T., Barbosa, J.S., Zweers, T., Champagne, D.L., Schouten, T., Meijer, O.C., de Kloet, E.R., Fitzsimons, C.P. , MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain, Endocrinology, vol. 150, no. 5, pp. 2220-2228. DOI
Champagne, D.L., de Kloet, E.R., Joels, M. , Fundamental aspects of the impact of glucocorticoids on the (immature) brain, Semin Fetal Neonatal Med, vol. 14, no. 3, pp. 136-142. DOI
de Jong, I.E., Steenbergen, P.J., de Kloet, E.R. , Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine, Psychopharmacology, vol. 204, no. 4, pp. 693-703. DOI
Dijkmans, T.F., van Hooijdonk, L.W., Schouten, T.G., Kamphorst, J.T., Fitzsimons, C.P., Vreugdenhil, E. , Identification of new Nerve Growth Factor-responsive immediate-early genes, Brain Res, vol. 1249, pp. 19-33. DOI
Sarabdjitsingh, R.A., Meijer, O.C., Schaaf, M.J., de Kloet, E.R. , Subregion-specific differences in translocation patterns of mineralocorticoid and glucocorticoid receptors in rat hippocampus, Brain Res, vol. 1249, pp. 43-53. DOI
Natarajan, D., de Vries, H., Saaltink, D.J., de Boer, S.F., Koolhaas, J.M. , Delineation of violence from functional aggression in mice: an ethological approach, Behav Genet, vol. 39, no. 1, pp. 73-90. DOI
Breuer, M.E., van Gaalen, M.M., Wernet, W., Claessens, S.E., Oosting, R.S., Behl, B., Korte, S.M., Schoemaker, H., Gross, G., Olivier, B., Groenink, L. , SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model, Naunyn Schmiedebergs Arch Pharmacol, vol. 379, no. 1, pp. 101-106. DOI
de Jong, I.E., de Kloet, E.R. , Critical time-window for the actions of adrenal glucocorticoids in behavioural sensitisation to cocaine, Eur J Pharmacol, vol. 604, no. 1-3, pp. 66-73. DOI
Fitzsimons, C.P., van Hooijdonk, L.W., Morrow, J.A., Peeters, B.W., Hamilton, N., Craighead, M., Vreugdenhil, E. , Antiglucocorticoids, neurogenesis and depression, Mini Rev Med Chem, vol. 9, no. 2, pp. 249-264.
Revsin, Y., Rekers, N.V., Louwe, M.C., Saravia, F.E., De Nicola, A.F., de Kloet, E.R., Oitzl, M.S. , Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice, Neuropsychopharmacology, vol. 34, no. 3, pp. 747-758. DOI
Daskalakis, N.P., Kaperoni, M., Koros, C., de Kloet, E.R., Kitraki, E. , Environmental and tactile stimulation modulates the neonatal handling effect on adult rat spatial memory, Int J Dev Neurosci, vol. 27, no. 8, pp. 747-755. DOI
Datson, N.A., Morsink, M.C., Steenbergen, P.J., Aubert, Y., Schlumbohm, C., Fuchs, E., de Kloet, E.R. , A molecular blueprint of gene expression in hippocampal subregions CA1, CA3, and DG is conserved in the brain of the common marmoset, Hippocampus, vol. 19, no. 8, pp. 739-752. DOI
Brinks, V., Berger, S., Gass, P., de Kloet, E.R., Oitzl, M.S. , Mineralocorticoid receptors in control of emotional arousal and fear memory, Horm Behav, vol. 56, no. 2, pp. 232-238. DOI
Brinks, V., de Kloet, E.R., Oitzl, M.S. , Corticosterone facilitates extinction of fear memory in BALB/c mice but strengthens cue related fear in C57BL/6 mice, Exp Neurol, vol. 216, no. 2, pp. 375-382. DOI
van Hooijdonk, L.W., Ichwan, M., Dijkmans, T.F., Schouten, T.G., de Backer, M.W., Adan, R.A., Verbeek, F.J., Vreugdenhil, E., Fitzsimons, C.P. , Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression, BMC Neurosci, vol. 10, no. 2, pp. 1-19. DOI
Bagot, R.C., van Hasselt, F.N., Champagne, D.L., Meaney, M.J., Krugers, H.J., Joels, M. , Maternal care determines rapid effects of stress mediators on synaptic plasticity in adult rat hippocampal dentate gyrus, Neurobiol Learn Mem, vol. 92, no. 3, pp. 292-300. DOI
Brittijn, S.A., Duivesteijn, S.J., Belmamoune, M., Bertens, L.F., Bitter, W., de Bruijn, J.D., Champagne, D.L., Cuppen, E., Flik, G., Vandenbroucke-Grauls, C.M., Janssen, R.A., de Jong, I.M., de Kloet, E.R., Kros, A., Meijer, A.H., Metz, J.R., van der Sar, A.M., Schaaf, M.J., Schulte-Merker, S., Spaink, H.P., Tak, P.P., Verbeek, F.J., Vervoordeldonk, M.J., Vonk, F.J., Witte, F., Yuan, H., Richardson, M.K. , Zebrafish development and regeneration: new tools for biomedical research, Int J Dev Biol, vol. 53, no. 5-6, pp. 835-850. DOI
2008
van der Laan, S., Sarabdjitsingh, R.A., Van Batenburg, M.F., Lachize, S.B., Li, H., Dijkmans, T.F., Vreugdenhil, E., de Kloet, E.R., Meijer, O.C. , Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain, J Neurochem, vol. 106, no. 6, pp. 2515-2523. DOI
Dalm, S., Brinks, V., van der Mark, M.H., de Kloet, E.R., Oitzl, M.S. , Non-invasive stress-free application of glucocorticoid ligands in mice, J Neurosci Methods, vol. 170, no. 1, pp. 77-84. DOI
de Jong, I.E., Steenbergen, P.J., de Kloet, E.R. , Strain differences in the effects of adrenalectomy on the midbrain dopamine system: implication for behavioral sensitization to cocaine, Neuroscience, vol. 153, no. 3, pp. 594-604. DOI
de Rijk, R.H., van Leeuwen, N., Klok, M.D., Zitman, F.G. , Corticosteroid receptor-gene variants: modulators of the stress-response and implications for mental health, Eur J Pharmacol, vol. 585, no. 2-3, pp. 492-501. DOI
de Kloet, E.R., de Jong, I.E., Oitzl, M.S. , Neuropharmacology of glucocorticoids: focus on emotion, cognition and cocaine, Eur J Pharmacol, vol. 585, no. 2-3, pp. 473-482. DOI
de Kloet, E.R., Karst, H., Joels, M. , Corticosteroid hormones in the central stress response: quick-and-slow, Front Neuroendocrinol, vol. 29, no. 2, pp. 268-272. DOI
Olijslagers, J.E., de Kloet, E.R., Elgersma, Y., van Woerden, G.M., Joels, M., Karst, H. , Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors, Eur J Neurosci, vol. 27, no. 10, pp. 2542-2550. DOI
van der Veen, R., Abrous, D.N., de Kloet, E.R., Piazza, P.V., Koehl, M. , Impact of intra- and interstrain cross-fostering on mouse maternal care, Genes Brain Behav, vol. 7, no. 2, pp. 184-192. DOI
Champagne, D.L., Bagot, R.C., van Hasselt, F., Ramakers, G., Meaney, M.J., de Kloet, E.R., Joels, M., Krugers, H. , Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress, J Neurosci, vol. 28, no. 23, pp. 6037-6045. DOI
Enthoven, L., de Kloet, E.R., Oitzl, M.S. , Differential development of stress system (re)activity at weaning dependent on time of disruption of maternal care, Brain Res, vol. 1217, pp. 62-69. DOI
de Kloet, E.R. , About stress hormones and resilience to psychopathology, J Neuroendocrinol, vol. 20, no. 6, pp. 885-892. DOI
Revsin, Y., van Wijk, D., Saravia, F.E., Oitzl, M.S., De Nicola, A.F., de Kloet, E.R. , Adrenal hypersensitivity precedes chronic hypercorticism in streptozotocin-induced diabetes mice, Endocrinology, vol. 149, no. 7, pp. 3531-3539. DOI
de Kloet, E.R., Sarabdjitsingh, R.A. , Everything has rhythm: focus on glucocorticoid pulsatility, Endocrinology, vol. 149, no. 7, pp. 3241-3243. DOI
Joels, M., Karst, H., de Rijk, R.H., de Kloet, E.R. , The coming out of the brain mineralocorticoid receptor, Trends Neurosci, vol. 31, no. 1, pp. 1-7. DOI
Enthoven, L., de Kloet, E.R., Oitzl, M.S. , Effects of maternal deprivation of CD1 mice on performance in the water maze and swim stress, Behav Brain Res, vol. 187, no. 1, pp. 195-199. DOI
van der Laan, S., Lachize, S.B., Vreugdenhil, E., de Kloet, E.R., Meijer, O.C. , Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene, Endocrinology, vol. 149, no. 2, pp. 725-732. DOI
Fitzsimons, C.P., Ahmed, S., Wittevrongel, C.F., Schouten, T.G., Dijkmans, T.F., Scheenen, W.J., Schaaf, M.J., de Kloet, E.R., Vreugdenhil, E. , The microtubule-associated protein doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells, Mol Endocrinol, vol. 22, no. 2, pp. 248-262. DOI
Enthoven, L., Oitzl, M.S., Koning, N., van der Mark, M.H., de Kloet, E.R. , Hypothalamic-pituitary-adrenal axis activity of newborn mice rapidly desensitizes to repeated maternal absence but becomes highly responsive to novelty, Endocrinology, vol. 149, no. 12, pp. 6366-6377. DOI
Datson, N.A., Morsink, M.C., Meijer, O.C., de Kloet, E.R. , Central corticosteroid actions: Search for gene targets, Eur J Pharmacol, vol. 583, no. 2-3, pp. 272-289. DOI
de Kloet, E.R., Han, F., Meijer, O.C. , From the stalk to down under about brain glucocorticoid receptors, stress and development, Neurochem Res, vol. 33, no. 4, pp. 637-642. DOI
Revsin, Y. , Type 1 Diabetes, Glucocorticoids and the Brain: a sweet connection, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University.
Beauquis, J., Homo-Delarche, F., Revsin, Y., De Nicola, A.F., Saravia, F. , Brain alterations in autoimmune and pharmacological models of diabetes mellitus: focus on hypothalamic-pituitary-adrenocortical axis disturbances, Neuroimmunomodulation, vol. 15, no. 1, pp. 61-67. DOI
Boekhoorn, K., Sarabdjitsingh, R.A., Kommerie, H., de Punder, K., Schouten, T.G., Lucassen, P.J., Vreugdenhil, E. , Doublecortin (DCX) and doublecortin-like (DCL) are differentially expressed in the early but not late stages of murine neocortical development, J Comp Neurol, vol. 507, no. 4, pp. 1639-1652. DOI
Schaaf, M.J., Champagne, D.L., van Laanen, I, van Wijk, D.C., Meijer, A.H., Meijer, O.C., Spaink, H.P., Richardson, M.K. , Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish, Endocrinology, vol. 149, no. 4, pp. 1591-1599. DOI
Topic, B., Oitzl, M.S., Meijer, O.C., Huston, J.P., Silva, M.A.D. , Differential Susceptibility to Extinction-Induced Despair and Age-Dependent Alterations in the Hypothalamic-Pituitary-Adrenal Axis and Neurochemical Parameters, Neuropsychobiology, vol. 58, no. 3-4, pp. 138-153. DOI
Ter Horst, J.P., Loscher, J.S., Pickering, M., Regan, C.M., Murphy, K.J. , Learning-associated regulation of polysialylated neural cell adhesion molecule expression in the rat prefrontal cortex is region-, cell type- and paradigm-specific, Eur J Neurosci, vol. 28, no. 3, pp. 419-427. DOI
van der Veen, R., Koehl, M., Abrous, D.N., de Kloet, E.R., Piazza, P.V., Deroche-Gamonet, V. , Maternal environment influences cocaine intake in adulthood in a genotype-dependent manner, PLoS One, vol. 3, no. 5, pp. 1-9. DOI
de Kloet, E.R. , Nothing is carved in stone, Tijdschr Psychiatr, vol. 50, no. 12, pp. 781-783. DOI
Frasca, A., Fumagalli, F., Ter Horst, J.P., Racagni, G., Murphy, K.J., Riva, M.A. , Olanzapine, but not haloperidol, enhances PSA-NCAM immunoreactivity in rat prefrontal cortex, Int J Neuropsychopharmacol, vol. 11, no. 5, pp. 591-595. DOI
Brinks, V., de Kloet, E.R., Oitzl, M.S. , Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice, Prog Brain Res, vol. 167, pp. 257-261. DOI
2007
Schmidt, M.V., Oitzl, M.S., Steenbergen, P.J., Lachize, S.B., Wurst, W., Muller, M.B., de Kloet, E.R., Meijer, O.C. , Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function, Brain Res, vol. 1174, pp. 1-6. DOI
Conway-Campbell, B.L., McKenna, M.A., Wiles, C.C., Atkinson, H.C., de Kloet, E.R., Lightman, S.L. , Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone, Endocrinology, vol. 148, no. 11, pp. 5470-5477. DOI
Morsink, M.C., Van Gemert, N.G., Steenbergen, P.J., Joels, M., De Kloet, E.R., Datson, N.A. , Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes, Brain Res, vol. 1150, pp. 14-20. DOI
Veenema, A.H., de Kloet, E.R., de Wilde, M.C., Roelofs, A.J., Kawata, M., Buwalda, B., Neumann, I.D., Koolhaas, J.M., Lucassen, P.J. , Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice, J Neuroendocrinol, vol. 19, no. 7, pp. 489-498. DOI
Berry, A., Capone, F., Giorgio, M., Pelicci, P.G., de Kloet, E.R., Alleva, E., Minghetti, L., Cirulli, F. , Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice, Exp Gerontol, vol. 42, no. 1-2, pp. 37-45. DOI
Sibug, R.M., Datson, N.A., Tijssen, A.M., Morsink, M.C., de Koning, J., de Kloet, E.R., Helmerhorst, F.M. , Effects of urinary and recombinant gonadotrophins on gene expression profiles during the murine peri-implantation period, Hum Reprod, vol. 22, no. 1, pp. 75-82. DOI
de Jong, I.E., Oitzl, M.S., de Kloet, E.R. , Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner, Behav Brain Res, vol. 177, no. 2, pp. 329-339. DOI
Schenk, G.J., Engels, B.M., Zhang, Y.P., Fitzsimons, C.P., Schouten, T., Kruidering, M., de Kloet, E.R., Vreugdenhil, E. , A potential role for calcium / calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence, Eur J Neurosci, vol. 26, no. 12, pp. 3411-3420. DOI
Oomen, C.A., Mayer, J.L., de Kloet, E.R., Joels, M., Lucassen, P.J. , Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress, Eur J Neurosci, vol. 26, no. 12, pp. 3395-3401. DOI
de Kloet, E.R. , Commentary: neuroendocrine basis, Prog Brain Res, vol. 167, pp. 53-62. DOI
Oitzl, M.S. , Commentary: behavioral phenotype, Prog Brain Res, vol. 167, pp. 111-117. DOI
Oitzl, M.S. , Avoidance, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 297-301. DOI
Brinks, V., van der Mark, M.H., de Kloet, E.R., Oitzl, M.S. , Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition, Neural Plast, vol. 2007, no. Articlr ID, pp. 1-11. DOI
Datson, N.A., Morsink, M.C., Atanasova, S., Armstrong, V.W., Zischler, H., Schlumbohm, C., Dutilh, B.E., Huynen, M.A., Waegele, B., Ruepp, A., de Kloet, E.R., Fuchs, E. , Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate, BMC Genomics, vol. 8, no. 190, pp. 1-9. DOI
Gorter, J.A., van Vliet, E.A., Rauwerda, H., Breit, T., Stad, R., van Schaik, L., Vreugdenhil, E., Redeker, S., Hendriksen, E., Aronica, E., Lopes da Silva, F.H., Wadman, W.J. , Dynamic changes of proteases and protease inhibitors revealed by microarray analysis in CA3 and entorhinal cortex during epileptogenesis in the rat, Epilepsia, vol. 48, no. Suppl-5, pp. 53-64. DOI
Vreugdenhil, E., Kolk, S.M., Boekhoorn, K., Fitzsimons, C.P., Schaaf, M.J., Schouten, T., Sarabdjitsingh, R.A., Sibug, R.M., Lucassen, P.J. , Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability, Eur J Neurosci, vol. 25, no. 3, pp. 635-648. DOI
2006
van Gemert, N.G., Meijer, O.C., Morsink, M.C., Joels, M. , Effect of brief corticosterone administration on SGK1 and RGS4 mRNA expression in rat hippocampus, Stress, vol. 9, no. 3, pp. 165-170. DOI
Schmidt, M.V., Deussing, J.M., Oitzl, M.S., Ohl, F., Levine, S., Wurst, W., Holsboer, F., Muller, M.B., de Kloet, E.R. , Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice, Eur J Neurosci, vol. 24, no. 8, pp. 2291-2298. DOI
Lucassen, P.J., Heine, V.M., Muller, M.B., van der Beek, E.M., Wiegant, V.M., De Kloet, E.R., Joels, M., Fuchs, E., Swaab, D.F., Czeh, B. , Stress, depression and hippocampal apoptosis, CNS Neurol Disord Drug Targets, vol. 5, no. 5, pp. 531-546. DOI
Schmidt, M.V., Levine, S., Alam, S., Harbich, D., Sterlemann, V., Ganea, K., de Kloet, E.R., Holsboer, F., Muller, M.B. , Metabolic signals modulate hypothalamic-pituitary-adrenal axis activation during maternal separation of the neonatal mouse, J Neuroendocrinol, vol. 18, no. 11, pp. 865-874. DOI
Morsink, M.C., Joels, M., Sarabdjitsingh, R.A., Meijer, O.C., De Kloet, E.R., Datson, N.A. , The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells, J Neurochem, vol. 99, no. 4, pp. 1282-1298. DOI
Feldker, D.E., Morsink, M.C., Veenema, A.H., Datson, N.A., Proutski, V., Lathouwers, D., de Kloet, E.R., Vreugdenhil, E. , The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates, Brain Res, vol. 1089, no. 1, pp. 10-20. DOI
van Gemert, N.G., van Riel, E., Meijer, O.C., Fehr, S., Schachner, M., Joels, M. , No effect of prolonged corticosterone over-exposure on NCAM, SGK1, and RGS4 mRNA expression in rat hippocampus, Brain Res, vol. 1093, no. 1, pp. 161-166. DOI
Herbert, J., Goodyer, I.M., Grossman, A.B., Hastings, M.H., de Kloet, E.R., Lightman, S.L., Lupien, S.J., Roozendaal, B., Seckl, J.R. , Do corticosteroids damage the brain?, J Neuroendocrinol, vol. 18, no. 6, pp. 393-411. DOI
Saravia, F.E., Beauquis, J., Revsin, Y., Homo-Delarche, F., de Kloet, E.R., De Nicola, A.F. , Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment, Cell Mol Neurobiol, vol. 26, no. 4-6, pp. 943-957. DOI
De Rijk, R.H., Wust, S., Meijer, O.C., Zennaro, M.C., Federenko, I.S., Hellhammer, D.H., Giacchetti, G., Vreugdenhil, E., Zitman, F.G., de Kloet, E.R. , A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness, J Clin Endocrinol Metab, vol. 91, no. 12, pp. 5083-5089. DOI
Mayer, J.L., Klumpers, L., Maslam, S., de Kloet, E.R., Joels, M., Lucassen, P.J. , Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis, J Neuroendocrinol, vol. 18, no. 8, pp. 629-631. DOI
Morsink, M.C., Steenbergen, P.J., Vos, J.B., Karst, H., Joels, M., De Kloet, E.R., Datson, N.A. , Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time, J Neuroendocrinol, vol. 18, no. 4, pp. 239-252. DOI
Bekker, M.N., van den Akker, N.M., Bartelings, M.M., Arkesteijn, J.B., Fischer, S.G., Polman, J.A., Haak, M.C., Webb, S., Poelmann, R.E., van Vugt, J.M., Gittenberger-de Groot, A.C. , Nuchal edema and venous-lymphatic phenotype disturbance in human fetuses and mouse embryos with aneuploidy, J Soc Gynecol Investig, vol. 13, no. 3, pp. 209-216. DOI
Wright, R.L., Lightner, E.N., Harman, J.S., Meijer, O.C., Conrad, C.D. , Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory, Eur J Neurosci, vol. 24, no. 2, pp. 595-605. DOI
Joels, M., Pu, Z., Wiegert, O., Oitzl, M.S., Krugers, H.J. , Learning under stress: how does it work?, Trends Cogn Sci, vol. 10, no. 4, pp. 152-158. DOI
Hoekstra, M., Stitzinger, M., van Wanrooij, E.J., Michon, I.N., Kruijt, J.K., Kamphorst, J., Van Eck, M., Vreugdenhil, E., Van Berkel, T.J., Kuiper, J. , Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet, J Lipid Res, vol. 47, no. 10, pp. 2198-2207. DOI
Haller, J., Kruk, M.R. , Normal and abnormal aggression: human disorders and novel laboratory models, Neurosci Biobehav Rev, vol. 30, no. 3, pp. 292-303. DOI
de Rijk, R.H., De Kloet, E.R. , Stress, glucocorticoids, and the brain, Nutrients, stress, and medical disorders, Totowa, N.J, Humana Press, pp. 111-135. DOI
de Jong, I.E.M., van den Buuse, M. , SCH 23390 in the prefrontal cortex enhances the effect of apomorphine on prepulse inhibition of rats, Neuropharmacology, vol. 51, no. 3, pp. 438-446. DOI
Meijer, O.C., van der Laan, S., Lachize, S.B., Steenbergen, P.J., de Kloet, E.R. , Steroid receptor coregulator diversity: what can it mean for the stressed brain?, Neuroscience, vol. 138, no. 3, pp. 891-899. DOI
Meijer, O.C. , Understanding stress through the genome, Stress, vol. 9, no. 2, pp. 61-67. DOI
2005
van der Laan, S., Lachize, S.B., Schouten, T.G., Vreugdenhil, E., de Kloet, E.R., Meijer, O.C. , Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain, Brain Res, vol. 1059, no. 2, pp. 113-121. DOI
Revsin, Y., Saravia, F., Roig, P., Lima, A., de Kloet, E.R., Homo-Delarche, F., De Nicola, A.F. , Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes, Brain Res, vol. 1038, no. 1, pp. 22-31. DOI
Schmidt, M.V., Levine, S., Oitzl, M.S., van der Mark, M.H., Muller, M.B., Holsboer, F., de Kloet, E.R. , Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse, Endocrinology, vol. 146, no. 3, pp. 1458-1464. DOI
Meijer, O.C., Kalkhoven, E., van der Laan, S., Steenbergen, P.J., Houtman, S.H., Dijkmans, T.F., Pearce, D., de Kloet, E.R. , Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling, Endocrinology, vol. 146, no. 3, pp. 1438-1448. DOI
Sibug, R.M., de Koning, J., Tijssen, A.M., de Ruiter, M.C., de Kloet, E.R., Helmerhorst, F.M. , Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period, Hum Reprod, vol. 20, no. 3, pp. 649-656. DOI
de Kloet, E.R., Joels, M., Holsboer, F. , Stress and the brain: from adaptation to disease, Nat Rev Neurosci, vol. 6, no. 6, pp. 463-475. DOI
Veenema, A.H., Sijtsma, B., Koolhaas, J.M., de Kloet, E.R. , The stress response to sensory contact in mice: genotype effect of the stimulus animal, Psychoneuroendocrinology, vol. 30, no. 6, pp. 550-557. DOI
Karssen, A.M., Meijer, O.C., Berry, A., Sanjuan Pinol, R., de Kloet, E.R. , Low doses of dexamethasone can produce a hypocorticosteroid state in the brain, Endocrinology, vol. 146, no. 12, pp. 5587-5595. DOI
de Kloet, E.R., Sibug, R.M., Helmerhorst, F.M., Schmidt, M.V. , Stress, genes and the mechanism of programming the brain for later life, Neurosci Biobehav Rev, vol. 29, no. 2, pp. 271-281. DOI
Dalm, S., Enthoven, L., Meijer, O.C., van der Mark, M.H., Karssen, A.M., de Kloet, E.R., Oitzl, M.S. , Age-related changes in hypothalamic-pituitary-adrenal axis activity of male C57BL/6J mice, Neuroendocrinology, vol. 81, no. 6, pp. 372-380. DOI
Meijer, O.C., Topic, B., Steenbergen, P.J., Jocham, G., Huston, J.P., Oitzl, M.S. , Correlations between hypothalamus-pituitary-adrenal axis parameters depend on age and learning capacity, Endocrinology, vol. 146, no. 3, pp. 1372-1381. DOI
Ingram, N., Martin, S., Wang, J.H., van der Laan, S., Loiacono, R., van den Buuse, M. , Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice, Neuropharmacology, vol. 48, no. 1, pp. 80-92. DOI
2004
Datson, N.A., Meijer, L., Steenbergen, P.J., Morsink, M.C., van der Laan, S., Meijer, O.C., de Kloet, E.R. , Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression, Eur J Neurosci, vol. 20, no. 10, pp. 2541-2554. DOI
Veenema, A.H., Koolhaas, J.M., de Kloet, E.R. , Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines, Ann N Y Acad Sci, vol. 1018, pp. 255-265. DOI
de Jong, I.E., de Kloet, E.R. , Glucocorticoids and vulnerability to psychostimulant drugs: toward substrate and mechanism, Ann N Y Acad Sci, vol. 1018, pp. 192-198. DOI
De Kloet, E.R. , Hormones and the stressed brain, Ann N Y Acad Sci, vol. 1018, pp. 1-15. DOI
van Riel, E., van Gemert, N.G., Meijer, O.C., Joels, M. , Effect of early life stress on serotonin responses in the hippocampus of young adult rats, Synapse, vol. 53, no. 1, pp. 11-19. DOI
Grootendorst, J., Enthoven, L., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice, Behav Brain Res, vol. 148, no. 1-2, pp. 167-177. DOI
Schmidt, M.V., Enthoven, L., van Woezik, J.H., Levine, S., de Kloet, E.R., Oitzl, M.S. , The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation, J Neuroendocrinol, vol. 16, no. 1, pp. 52-57. DOI
Karssen, A.M., Meijer, O.C., Pons, D., De Kloet, E.R. , Localization of mRNA expression of P-glycoprotein at the blood-brain barrier and in the hippocampus, Ann N Y Acad Sci, vol. 1032, pp. 308-311. DOI
Enthoven, L., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Swim posture of mice does not affect performance in the water maze, Brain Res, vol. 1003, no. 1-2, pp. 36-41. DOI
Blain, J.F., Paradis, E., Gaudreault, S.B., Champagne, D.L., Richard, D., Poirier, J. , A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain, Neurobiol Dis, vol. 15, no. 3, pp. 510-9. DOI
Schmidt, M.V. , Stress system development: Molecular mechanisms of activation and inhibition, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, pp. 186.
Haller, J., Halasz, J., Mikics, E., Kruk, M.R. , Chronic glucocorticoid deficiency-induced abnormal aggression, autonomic hypoarousal, and social deficit in rats, J Neuroendocrinol, vol. 16, no. 6, pp. 550-557. DOI
Engels, B.M., Schouten, T.G., van Dullemen, J., Gosens, I, Vreugdenhil, E. , Functional differences between two DCLK splice variants, Brain Res Mol Brain Res, vol. 120, no. 2, pp. 103-114. DOI
Kruk, M.R., Halasz, J., Meelis, W., Haller, J. , Fast positive feedback between the adrenocortical stress response and a brain mechanism involved in aggressive behavior, Behav Neurosci, vol. 118, no. 5, pp. 1062-1070. DOI
Mulder, M., Jansen, P.J., Janssen, B.J., van de Berg, W.D., van der Boom, H., Havekes, L.M., De Kloet, E.R., Ramaekers, F.C., Blokland, A. , Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus, Neurobiol Dis, vol. 16, no. 1, pp. 212-219. DOI
van der Beek, E.M., Wiegant, V.M., Schouten, W.G., van Eerdenburg, F.J., Loijens, L.W., van der Plas, C., Benning, M.A., de Vries, H., de Kloet, E.R., Lucassen, P.J. , Neuronal number, volume, and apoptosis of the left dentate gyrus of chronically stressed pigs correlate negatively with basal saliva cortisol levels, Hippocampus, vol. 14, no. 6, pp. 688-700. DOI
Saravia, F.E., Revsin, Y., Lux-Lantos, V., Beauquis, J., Homo-Delarche, F., De Nicola, A.F. , Oestradiol restores cell proliferation in dentate gyrus and subventricular zone of streptozotocin-diabetic mice, J Neuroendocrinol, vol. 16, no. 8, pp. 704-710. DOI
Flugge, G., Van Kampen, M., Mijnster, M.J. , Perturbations in brain monoamine systems during stress, Cell Tissue Res, vol. 315, no. 1, pp. 1-14. DOI
Heilbronner, U., Van Kampen, M., Flugge, G. , The alpha-2B adrenoceptor in the paraventricular thalamic nucleus is persistently upregulated by chronic psychosocial stress, Cell Mol Neurobiol, vol. 24, no. 6, pp. 815-831. DOI
2003
Feldker, D.E., de Kloet, E.R., Kruk, M.R., Datson, N.A. , Large-scale gene expression profiling of discrete brain regions: potential, limitations, and application in genetics of aggressive behavior, Behav Genet, vol. 33, no. 5, pp. 537-48. DOI
Spaargaren, M., Beuling, E.A., Rurup, M.L., Meijer, H.P., Klok, M.D., Middendorp, S., Hendriks, R.W., Pals, S.T. , The B cell antigen receptor controls integrin activity through Btk and PLCgamma2, J Exp Med, vol. 198, no. 10, pp. 1539-1550. DOI
Bredy, T.W., Grant, R.J., Champagne, D.L., Meaney, M.J. , Maternal care influences neuronal survival in the hippocampus of the rat, Eur J Neurosci, vol. 18, no. 10, pp. 2903-9. DOI
de Kloet, E.R., Oitzl, M.S. , Who cares for a stressed brain? The mother, the kid or both?, Neurobiol Aging, vol. 24 Suppl 1, pp. S61-5; discussion S67-8. DOI
Schmidt, M.V., Enthoven, L., van der Mark, M.H., Levine, S., de Kloet, E.R., Oitzl, M.S. , The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse, Int J Dev Neurosci, vol. 21, no. 3, pp. 125-132. DOI
Veenema, A.H., Meijer, O.C., de Kloet, E.R., Koolhaas, J.M. , Genetic selection for coping style predicts stressor susceptibility, J Neuroendocrinol, vol. 15, no. 3, pp. 256-67. DOI
de Kloet, E.R. , Hormones, brain and stress, Endocr Regul, vol. 37, no. 2, pp. 51-68.
Meijer, O.C., Karssen, A.M., de Kloet, E.R. , Cell- and tIssue-specific effects of corticosteroids in relation to glucocorticoid resistance: examples from the brain, J Endocrinol, vol. 178, no. 1, pp. 13-18. DOI
Veenema, A.H., Meijer, O.C., de Kloet, E.R., Koolhaas, J.M., Bohus, B.G. , Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression, Horm Behav, vol. 43, no. 1, pp. 197-204. DOI
Feldker, D.E., Datson, N.A., Veenema, A.H., Meulmeester, E., de Kloet, E.R., Vreugdenhil, E. , Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice, Eur J Neurosci, vol. 17, no. 2, pp. 379-387. DOI
Feldker, D.E., Datson, N.A., Veenema, A.H., Proutski, V., Lathouwers, D., De Kloet, E.R., Vreugdenhil, E. , GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications, J Neurosci Res, vol. 74, no. 5, pp. 701-16. DOI
Arbesman, S., Enthoven, L., Monteiro, A. , Ancient Wings: animating the evolution of butterfly wing patterns, Biosystems, vol. 71, no. 3, pp. 289-295. DOI
Flugge, G., Van Kampen, M., Meyer, H., Fuchs, E. , Alpha2A and alpha2C-adrenoceptor regulation in the brain: alpha2A changes persist after chronic stress, Eur J Neurosci, vol. 17, no. 5, pp. 917-928. DOI
Jonker, D.M., van de Mheen, C., Eilers, P.H., Kruk, M.R., Voskuyl, R.A., Danhof, M. , Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat, Behav Neurosci, vol. 117, no. 5, pp. 1076-1085. DOI
van Riel, E., Meijer, O.C., Steenbergen, P.J., Joels, M. , Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons, Neuroscience, vol. 120, no. 3, pp. 649-658. DOI
Qin, Y., Nair, S., Karst, H., Vreugdenhil, E., Datson, N.A., Joels, M. , Gene expression changes in single dentate granule neurons after adrenalectomy of rats, Mol Brain Res, vol. 111, no. 1-2, pp. 17-23. DOI
Schmidt, M.V., Oitzl, M.S., Muller, M.B., Ohl, F., Wurst, W., Holsboer, F., Levine, S., De Kloet, E.R. , Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice, Neuroscience, vol. 119, no. 2, pp. 589-595. DOI
Champagne, D.L., Pearson, D., Dea, D., Rochford, J., Poirier, J. , The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease, Neuroscience, vol. 121, no. 1, pp. 99-110. DOI
2002
Grootendorst, J., Kempes, M.M., Lucassen, P.J., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Differential effect of corticosterone on spatial learning abilities in apolipoprotein E knockout and C57BL/6J mice, Brain Res, vol. 953, no. 1-2, pp. 281-285. DOI
Karssen, A.M., Meijer, O.C., van der Sandt, I.C., De Boer, A.G., De Lange, E.C., De Kloet, E.R. , The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone, J Endocrinol, vol. 175, no. 1, pp. 251-260. DOI
Sibug, R.M., Helmerhorst, F.M., Tijssen, A.M., de Kloet, E.R., de Koning, J. , Estrogen reduces vascular endothelial growth factor(164) expression in the mouse nucleus paraventricularis of the hypothalamus, Neurosci Lett, vol. 333, no. 3, pp. 199-202. DOI
Schmidt, M.V., Oitzl, M.S., Levine, S., de Kloet, E.R. , The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation, Brain Res Dev Brain Res, vol. 139, no. 1, pp. 39-49. DOI
de Kloet, E.R., Grootendorst, J., Karssen, A.M., Oitzl, M.S. , Gene x environment interaction and cognitive performance: animal studies on the role of corticosterone, Neurobiol Learn Mem, vol. 78, no. 3, pp. 570-7. DOI
Sibug, R.M., Helmerhorst, F.M., Tijssen, A.M., de Kloet, E.R., de Koning, J. , Gonadotrophin stimulation reduces VEGF(120) expression in the mouse uterus during the peri-implantation period, Hum Reprod, vol. 17, no. 6, pp. 1643-1648. DOI
van Acker, S.A., Oitzl, M.S., Fluttert, M.F., de Kloet, E.R. , Centrally regulated blood pressure response to vasoactive peptides is modulated by corticosterone, J Neuroendocrinol, vol. 14, no. 1, pp. 56-63. DOI
Rahmouni, K., Sibug, R.M., De Kloet, E.R., Barthelmebs, M., Grima, M., Imbs, J.L., De Jong, W. , Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension, Eur J Pharmacol, vol. 436, no. 3, pp. 207-16. DOI
van den Buuse, M., van Acker, S.A., Fluttert, M.F., de Kloet, E.R. , Involvement of corticosterone in cardiovascular responses to an open-field novelty stressor in freely moving rats, Physiol Behav, vol. 75, no. 1-2, pp. 207-15. DOI
Van Kampen, M., De Kloet, E.R., Flugge, G., Fuchs, E. , Blockade of glucocorticoid receptors with ORG 34116 does not normalize stress-induced symptoms in male tree shrews, Eur J Pharmacol, vol. 457, no. 2-3, pp. 207-16. DOI
Evans, S.J., Datson, N.A., Kabbaj, M., Thompson, R.C., Vreugdenhil, E., De Kloet, E.R., Watson, S.J., Akil, H. , Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis. Serial Analysis of Gene Expression, Eur J Neurosci, vol. 16, no. 3, pp. 409-413. DOI
Horvath, K.M., Hartig, W., van der Veen, R., Keijser, J.N., Mulder, J., Ziegert, M., Van der Zee, E.A., Harkany, T., Luiten, P.G.M. , 17 beta-estradiol enhances cortical cholinergic innervation and preserves synaptic density following excitotoxic lesions to the rat nucleus basalis magnocellularis, Neuroscience, vol. 110, no. 3, pp. 489-504. DOI
Champagne, D.L., Dupuy, J.B., Rochford, J., Poirier, J. , Apolipoprotein E knockout mice display procedural deficits in the Morris water maze: analysis of learning strategies in three versions of the task, Neuroscience, vol. 114, no. 3, pp. 641-54. DOI
Meijer, O.C. , Coregulator proteins and corticosteroid action in the brain, J Neuroendocrinol, vol. 14, no. 6, pp. 499-505. DOI
Saravia, F.E., Pietranera, L., Lima, A., Roig, P., Revsin, Y., De Nicola, A.F. , Deoxycorticosterone stimulates the activity of nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase immunoreactivity in hypothalamic nuclei of rats, Neurosci Lett, vol. 329, no. 3, pp. 344-348. DOI
Halasz, J., Liposits, Z., Meelis, W., Kruk, M.R., Haller, J. , Hypothalamic attack area-mediated activation of the forebrain in aggression, Neuroreport, vol. 13, no. 10, pp. 1267-1270.
van Riel, E., Meijer, O.C., Veenema, A.H., Joels, M. , Hippocampal serotonin responses in short and long attack latency mice, J Neuroendocrinol, vol. 14, no. 3, pp. 234-239. DOI
Saravia, F.E., Revsin, Y., Gonzalez Deniselle, M.C., Gonzalez, S.L., Roig, P., Lima, A., Homo-Delarche, F., De Nicola, A.F. , Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice, Brain Res, vol. 957, no. 2, pp. 345-353. DOI
Schmidt, M.V., Okimoto, D.K., Dent, G.W., Gordon, M.K., Levine, S. , Maternal regulation of the hypothalamic-pituitary-adrenal axis in the 20-day-old rat: consequences of laboratory weaning, J Neuroendocrinol, vol. 14, no. 6, pp. 450-457. DOI
Halasz, J., Liposits, Z., Kruk, M.R., Haller, J. , Neural background of glucocorticoid dysfunction-induced abnormal aggression in rats: involvement of fear- and stress-related structures, Eur J Neurosci, vol. 15, no. 3, pp. 561-569. DOI
Bartolomucci, A., de Biurrun, G., Czeh, B., Van Kampen, M., Fuchs, E. , Selective enhancement of spatial learning under chronic psychosocial stress, Eur J Neurosci, vol. 15, no. 11, pp. 1863-1866. DOI
De Kloet, E.R. , Stress in the brain: implications for treatment of depression, Acta Neuropsychiatrica, vol. 14, no. 4, pp. 155-166. DOI
Van Kampen, M., Kramer, M., Hiemke, C., Flugge, G., Fuchs, E. , The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders, Stress, vol. 5, no. 1, pp. 37-46. DOI
2001
Van Acker, S.A., Fluttert, M.F., Sibug, R.M., De Kloet, E.R. , Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses to brief restraint stress, Eur J Pharmacol, vol. 430, no. 1, pp. 87-91. DOI
Oitzl, M.S., Reichardt, H.M., Joels, M., de Kloet, E.R. , Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory, PNAS, vol. 98, no. 22, pp. 12790-12795. DOI
Vreugdenhil, E., Engels, B.M., Middelburg, R., van Koningsbruggen, S., Knol, J., Veldhuisen, B., de Kloet, E.R. , Multiple transcripts generated by the DCAMKL gene are expressed in the rat hippocampus, Brain Res Mol Brain Res, vol. 94, no. 1-2, pp. 67-74. DOI
Schaaf, M.J., Workel, J.O., Lesscher, H.M., Vreugdenhil, E., Oitzl, M.S., de Kloet, E.R. , Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats, Brain Res, vol. 915, no. 2, pp. 227-33. DOI
Grootendorst, J., de Kloet, E.R., Vossen, C., Dalm, S., Oitzl, M.S. , Repeated exposure to rats has persistent genotype-dependent effects on learning and locomotor activity of apolipoprotein E knockout and C57Bl/6 mice, Behav Brain Res, vol. 125, no. 1-2, pp. 249-59. DOI
De Rijk, R.H., Schaaf, M.J., Turner, G., Datson, N.A., Vreugdenhil, E., Cidlowski, J., de Kloet, E.R., Emery, P., Sternberg, E.M., Detera-Wadleigh, S.D. , A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis, J Rheumatol, vol. 28, no. 11, pp. 2383-8.
Grootendorst, J., Oitzl, M.S., Dalm, S., Enthoven, L., Schachner, M., de Kloet, E.R., Sandi, C. , Stress alleviates reduced expression of cell adhesion molecules (NCAM, L1), and deficits in learning and corticosterone regulation of apolipoprotein E knockout mice, Eur J Neurosci, vol. 14, no. 9, pp. 1505-1514. DOI
van den Buuse, M., Van Acker, S.A., Fluttert, M.F., De Kloet, E.R. , Blood pressure, heart rate, and behavioral responses to psychological "novelty" stress in freely moving rats, Psychophysiology, vol. 38, no. 3, pp. 490-499. DOI
Karssen, A.M., Meijer, O.C., van der Sandt, I.C., Lucassen, P.J., de Lange, E.C., de Boer, A.G., de Kloet, E.R. , Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain, Endocrinology, vol. 142, no. 6, pp. 2686-2694. DOI
Mulder, M., Blokland, A., van den Berg, D.J., Schulten, H., Bakker, A.H., Terwel, D., Honig, W., de Kloet, E.R., Havekes, L.M., Steinbusch, H.W., de Lange, E.C. , Apolipoprotein E protects against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging, Lab Invest, vol. 81, no. 7, pp. 953-60. DOI
Lucassen, P.J., Vollmann-Honsdorf, G.K., Gleisberg, M., Czeh, B., De Kloet, E.R., Fuchs, E. , Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew, Eur J Neurosci, vol. 14, no. 1, pp. 161-166. DOI
Workel, J.O., Oitzl, M.S., Fluttert, M.F., Lesscher, H., Karssen, A.M., de Kloet, E.R. , Differential and age-dependent effects of maternal deprivation on the hypothalamic-pituitary-adrenal axis of brown norway rats from youth to senescence, J Neuroendocrinol, vol. 13, no. 7, pp. 569-80. DOI
Vreugdenhil, E., de Kloet, E.R., Schaaf, M.J., Datson, N.A. , Genetic dissection of corticosterone receptor function in the rat hippocampus, Eur Neuropsychopharmacol, vol. 11, no. 6, pp. 423-30. DOI
Sibug, R.M., Oitzl, M.S., Workel, J.O., de Kloet, E.R. , Maternal deprivation increases 5-HT(1A) receptor expression in the CA1 and CA3 areas of senescent Brown Norway rats, Brain Res, vol. 912, no. 1, pp. 95-8. DOI
Datson, N.A., van der Perk, J., de Kloet, E.R., Vreugdenhil, E. , Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression, Eur J Neurosci, vol. 14, no. 4, pp. 675-689. DOI
Hendriksen, H., Datson, N.A., Ghijsen, W.E., van Vliet, E.A., da Silva, F.H., Gorter, J.A., Vreugdenhil, E. , Altered hippocampal gene expression prior to the onset of spontaneous seizures in the rat post-status epilepticus model, Eur J Neurosci, vol. 14, no. 9, pp. 1475-1484. DOI
Kruidering, M., Schouten, T., Evan, G. I, Vreugdenhil, E. , Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis, J Biol Chem, vol. 276, no. 42, pp. 38417-38425. DOI
Meyer, U., Van Kampen, M., Isovich, E., Flugge, G., Fuchs, E. , Chronic psychosocial stress regulates the expression of both GR and MR mRNA in the hippocampal formation of tree shrews, Hippocampus, vol. 11, no. 3, pp. 329-336. DOI
Haller, J., van de Schraaf, J., Kruk, M.R. , Deviant forms of aggression in glucocorticoid hyporeactive rats: a model for 'pathological' aggression?, J Neuroendocrinol, vol. 13, no. 1, pp. 102-107. DOI
Datson, N.A., van der Perk, J., de Kloet, E.R., Vreugdenhil, E. , Expression profile of 30,000 genes in rat hippocampus using SAGE, Hippocampus, vol. 11, no. 4, pp. 430-44. DOI
Hof, P.R., Mobbs, C.V. , Functional neurobiology of aging, , no. xxvii, 960, San Diego, Calif, Academic.
Kreeft, A.J., Moen, C.J., Hofker, M.H., Frants, R.R., Vreugdenhil, E., Gijbels, M.J., Havekes, L.M., Datson, N.A. , Identification of differentially regulated genes in mildly hyperlipidemic ApoE3-Leiden mice by use of serial analysis of gene expression, Arterioscler Thromb Vasc Biol, vol. 21, no. 12, pp. 1984-1990. DOI
Vis, P., Della Paschoa, O.E., Kruk, M.R., Martin, D., Mocaer, E., Danhof, M., Jochemsen, R. , Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-HT(1A) receptor agonist, using a behavioural model in rats, Eur J Pharmacol, vol. 414, no. 2-3, pp. 233-243. DOI
Grootendorst, J., de Kloet, E.R., Dalm, S., Oitzl, M.S. , Reversal of cognitive deficit of apolipoprotein E knockout mice after repeated exposure to a common environmental experience, Neuroscience, vol. 108, no. 2, pp. 237-47. DOI
Czeh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., Van Kampen, M., Bartolomucci, A., Fuchs, E. , Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine, PNAS, vol. 98, no. 22, pp. 12796-12801. DOI
2000
de Kloet, E.R. , Stress in the brain, Eur J Pharmacol, vol. 405, no. 1-3, pp. 187-98. DOI
Sibug, R.M., Compaan, J.C., Meijer, O.C., Van der Gugten, J., Olivier, B., De Kloet, E.R. , Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus, Eur J Pharmacol, vol. 404, no. 1-2, pp. 111-9. DOI
Karst, H., Karten, Y.J., Reichardt, H.M., de Kloet, E.R., Schutz, G., Joels, M. , Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers, Nat Neurosci, vol. 3, no. 10, pp. 977-8. DOI
Oitzl, M.S., Workel, J.O., Fluttert, M.F., Frosch, F., De Kloet, E.R. , Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats, Eur J Neurosci, vol. 12, no. 10, pp. 3771-3780. DOI
Schaaf, M.J., De Kloet, E.R., Vreugdenhil, E. , Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation, Stress, vol. 3, no. 3, pp. 201-208. DOI
Grootendorst, J., Mulder, M., Haasdijk, E., de Kloet, E.R., Jaarsma, D. , Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion, Brain Res, vol. 868, no. 2, pp. 165-75. DOI
Meijer, O.C., Steenbergen, P.J., De Kloet, E.R. , Differential expression and regional distribution of steroid receptor coactivators SRC-1 and SRC-2 in brain and pituitary, Endocrinology, vol. 141, no. 6, pp. 2192-2199. DOI
Schaaf, M.J., Duurland, R., de Kloet, E.R., Vreugdenhil, E. , Circadian variation in BDNF mRNA expression in the rat hippocampus, Brain Res Mol Brain Res, vol. 75, no. 2, pp. 342-344. DOI
Dalm, S., Grootendorst, J., de Kloet, E.R., Oitzl, M.S. , Quantification of swim patterns in the Morris water maze, Behav Res Methods Instrum Comput, vol. 32, no. 1, pp. 134-139. DOI
de Kloet, E.R., Van Acker, S.A., Sibug, R.M., Oitzl, M.S., Meijer, O.C., Rahmouni, K., de Jong, W. , Brain mineralocorticoid receptors and centrally regulated functions, Kidney Int, vol. 57, no. 4, pp. 1329-36. DOI
Bhatnagar, S., Viau, V., Chu, A., Soriano, L., Meijer, O.C., Dallman, M.F. , A cholecystokinin-mediated pathway to the paraventricular thalamus is recruited in chronically stressed rats and regulates hypothalamic-pituitary-adrenal function, J Neurosci, vol. 20, no. 14, pp. 5564-5573.
Fluttert, M.F., Dalm, S., Oitzl, M.S. , A refined method for sequential blood sampling by tail incision in rats, Lab Anim, vol. 34, no. 4, pp. 372-378. DOI
Van Kampen, M., Schmitt, U., Hiemke, C., Fuchs, E. , Diazepam has no beneficial effects on stress-induced behavioural and endocrine changes in male tree shrews, Pharmacol Biochem Behav, vol. 65, no. 3, pp. 539-546. DOI
Bhargava, A., Meijer, O.C., Dallman, M.F., Pearce, D. , Plasma membrane calcium pump isoform 1 gene expression is repressed by corticosterone and stress in rat hippocampus, J Neurosci, vol. 20, no. 9, pp. 3129-3138.
Pearce, D., Verrey, F., Chen, S.Y., Mastroberardino, L., Meijer, O.C., Wang, J., Bhargava, A. , Role of SGK in mineralocorticoid-regulated sodium transport, Kidney Int., vol. 57, no. 4, pp. 1283-1289. DOI
Wissink, S., Meijer, O.C., Pearce, D., van der Burg, B., van der Saag, P.T. , Regulation of the rat serotonin-1A receptor gene by corticosteroids, J Biol Chem, vol. 275, no. 2, pp. 1321-1326. DOI
Cabrera, R., Korte, S.M., Lentjes, E.G., Romijn, F., Schonbaum, E., De Nicola, A., De Kloet, E.R. , The amount of free corticosterone is increased during lipopolysaccharide-induced fever, Life Sci, vol. 66, no. 7, pp. 553-562. DOI
Haller, J., Millar, S., van de Schraaf, J., De Kloet, E.R., Kruk, M.R. , The active phase-related increase in corticosterone and aggression are linked, J Neuroendocrinol, vol. 12, no. 5, pp. 431-436. DOI
Meijer, O.C., Williamson, A., Dallman, M.F., Pearce, D. , Transcriptional repression of the 5-HT1A receptor promoter by corticosterone via mineralocorticoid receptors depends on the cellular context, J Neuroendocrinol, vol. 12, no. 3, pp. 245-254. DOI
Haller, J., Halasz, J., Mikics, E., Kruk, M.R., Makara, G.B. , Ultradian corticosterone rhythm and the propensity to behave aggressively in male rats, J Neuroendocrinol, vol. 12, no. 10, pp. 937-940. DOI
1999
de Kloet, E.R., Oitzl, M.S., Joels, M. , Stress and cognition: are corticosteroids good or bad guys?, Trends Neurosci, vol. 22, no. 10, pp. 422-6. DOI
Datson, N.A., van der Perk-de Jong, J., van den Berg, M.P., de Kloet, E.R., Vreugdenhil, E. , MicroSAGE: a modified procedure for serial analysis of gene expression in limited amounts of tissue, Nucleic Acids Res, vol. 27, no. 5, pp. 1300-1307. DOI
Saravia, F.E., Grillo, C.A., Ferrini, M., Roig, P., Lima, A.E., de Kloet, E.R., De Nicola, A.F. , Changes of hypothalamic and plasma vasopressin in rats with deoxycorticosterone-acetate induced salt appetite, J Steroid Biochem Mol Biol, vol. 70, no. 1-3, pp. 47-57. DOI
Engels, B.M., Lucassen, P.J., de Kloet, E.R., Vreugdenhil, E. , Regional distribution of a novel calcium/calmodulin-dependent protein kinase mRNA in the rat brain, Brain Res, vol. 835, no. 2, pp. 365-8. DOI
Schaaf, M.J., Sibug, R.M., Duurland, R., Fluttert, M.F., Oitzl, M.S., De Kloet, E.R., Vreugdenhil, E. , Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training, Stress, vol. 3, no. 2, pp. 173-183. DOI
van Oers, H.J., de Kloet, E.R., Levine, S. , Persistent effects of maternal deprivation on HPA regulation can be reversed by feeding and stroking, but not by dexamethasone, J Neuroendocrinol, vol. 11, no. 8, pp. 581-8. DOI
Vreugdenhil, E., Datson, N.A., Engels, B.M., de Jong, J., van Koningsbruggen, S., Schaaf, M.J., de Kloet, E.R. , Kainate-elicited seizures induce mRNA encoding a CaMK-related peptide: a putative modulator of kinase activity in rat hippocampus, J Neurobiol, vol. 39, no. 1, pp. 41-50. DOI
Kruk, M.R., Haller, J. , Corticosteroids and the escalation of violence in hypothalamic and territorial aggression in male rats, 5th IBRO world congress of neurosience: IBRO world congress, 11.-15.7.1999, pp. 36-36.
Danik, M., Champagne, D.L., Petit-Turcotte, C., Beffert, U., Poirier, J. , Brain lipoprotein metabolism and its relation to neurodegenerative disease, Crit Rev Neurobiol, vol. 13, no. 4, pp. 357-407.
Chen, S.Y., Bhargava, A., Mastroberardino, L., Meijer, O.C., Wang, J., Buse, P., Firestone, G.L., Verrey, F., Pearce, D. , Epithelial sodium channel regulated by aldosterone-induced protein sgk, PNAS, vol. 96, no. 5, pp. 2514-2519. DOI
Karten, Y.J.G., Nair, S.M., van Essen, L., Sibug, R.M., Joels, M. , Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons, PNAS, vol. 96, no. 23, pp. 13456-13461. DOI
Siegel, A., Roeling, T.A.P., Gregg, T.R., Kruk, M.R. , Neuropharmacology of brain-stimulation-evoked aggression, Neurosci Biobehav Rev, vol. 23, no. 3, pp. 359-389. DOI
Dallman, M.F., Akana, S.F., Bhatnagar, S., Bell, M.E., Choi, S., Chu, A., Horsley, C., Levin, N., Meijer, O.C., Soriano, L.R., Strack, A.M., Viau, V. , Starvation: early signals, sensors, and sequelae, Endocrinology, vol. 140, no. 9, pp. 4015-4023. DOI
1998
Betancur, C., Cabrera, R., de Kloet, E.R., Pelaprat, D., Rostene, W. , Role of endogenous neurotensin in the behavioral and neuroendocrine effects of cocaine, Neuropsychopharmacology, vol. 19, no. 4, pp. 322-32. DOI
Schaaf, M.J., de Jong, J., de Kloet, E.R., Vreugdenhil, E. , Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone, Brain Res, vol. 813, no. 1, pp. 112-120. DOI
Oitzl, M.S., Fluttert, M.F., de Kloet, E.R. , Acute blockade of hippocampal glucocorticoid receptors facilitates spatial learning in rats, Brain Res, vol. 797, no. 1, pp. 159-162. DOI
Meijer, O.C., Kortekaas, R., Oitzl, M.S., de Kloet, E.R. , Acute rise in corticosterone facilitates 5-HT(1A) receptor-mediated behavioural responses, Eur J Pharmacol, vol. 351, no. 1, pp. 7-14. DOI
van Oers, H.J., de Kloet, E.R., Li, C., Levine, S. , The ontogeny of glucocorticoid negative feedback: influence of maternal deprivation, Endocrinology, vol. 139, no. 6, pp. 2838-2846. DOI
Sibug, R.M., Compaan, J.C., Meijer, O.C., Van der Gugten, J., Olivier, B., De Kloet, E.R. , Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels, Eur J Pharmacol, vol. 353, no. 2-3, pp. 207-14. DOI
Champagne, D.L., Beaulieu, J., Drolet, G. , CRFergic innervation of the paraventricular nucleus of the rat hypothalamus: a tract-tracing study, J Neuroendocrinol, vol. 10, no. 2, pp. 119-31. DOI
Gomez, F., De Kloet, E.R., Armario, A. , Glucocorticoid negative feedback on the HPA axis in five inbred rat strains, Am J Physiol Regul Integr Comp Physiol, vol. 274, no. 2, pp. R420-R427.
van Oers, H.J., de Kloet, E.R., Levine, S. , Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress, Brain Res Dev Brain Res, vol. 111, no. 2, pp. 245-252. DOI
van Oers, H.J., de Kloet, E.R., Whelan, T., Levine, S. , Maternal deprivation effect on the infant's neural stress markers is reversed by tactile stimulation and feeding but not by suppressing corticosterone, J Neurosci, vol. 18, no. 23, pp. 10171-10179.
Oitzl, M.S., Fluttert, M.F., Sutanto, W., de Kloet, E.R. , Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats, Eur J Neurosci, vol. 10, no. 12, pp. 3759-3766. DOI
Grillo, C.A., Saravia, F., Ferrini, M., Piroli, G., Roig, P., Garcia, S. I, de Kloet, E.R., De Nicola, A.F. , Increased expression of magnocellular vasopressin mRNA in rats with deoxycorticosterone-acetate induced salt appetite, Neuroendocrinology, vol. 68, no. 2, pp. 105-115. DOI
Meijer, O.C., de Lange, E.C., Breimer, D.D., de Boer, A.G., Workel, J.O., de Kloet, E.R. , Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice, Endocrinology, vol. 139, no. 4, pp. 1789-1793. DOI
De Nicola, A.F., Ferrini, M., Gonzalez, S.L., Gonzalez Deniselle, M.C., Grillo, C.A., Piroli, G., Saravia, F., de Kloet, E.R. , Regulation of gene expression by corticoid hormones in the brain and spinal cord, J Steroid Biochem Mol Biol, vol. 65, no. 1-6, pp. 253-272. DOI
Haller, J., Abraham, I, Zelena, D., Juhasz, G., Makara, G.B., Kruk, M.R. , Aggressive experience affects the sensitivity of neurons towards pharmacological treatment in the hypothalamic attack area, Behavioural Pharmacology, vol. 9, no. 5-6, pp. 469-475.
Haller, J., Halasz, J., Makara, G.B., Kruk, M.R. , Acute effects of glucocorticoids: behavioral and pharmacological perspectives, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 337-344. DOI
Ohl, F., Oitzl, M.S., Fuchs, E. , Assessing cognitive functions in tree shrews: visuo-spatial and spatial learning in the home cage, J Neurosci Methods, vol. 81, no. 1-2, pp. 35-40. DOI
Van Kampen, M., Fuchs, E. , Age-related levels of urinary free cortisol in the tree shrew, Neurobiol Aging, vol. 19, no. 4, pp. 363-366. DOI
Haller, J., Makara, G.B., Kruk, M.R. , Catecholaminergic involvement in the control of aggression: hormones, the peripheral sympathetic, and central noradrenergic systems, Neurosci Biobehav Rev, vol. 22, no. 1, pp. 85-97. DOI
Joels, M., Vreugdenhil, E. , Corticosteroids in the brain. Cellular and molecular actions, Mol Neurobiol, vol. 17, no. 1-3, pp. 87-108. DOI
Della Paschoa, O.E., Kruk, M.R., Voskuyl, R.A., Danhof, M. , Effects of repeated seizure induction on seizure activity, post-ictal and interictal behavior, Brain Res, vol. 814, no. 1-2, pp. 199-208. DOI
van Kesteren, R.E., Fainzilber, M., Hauser, G., van Minnen, J., Vreugdenhil, E., Smit, A.B., Ibanez, C.F., Geraerts, W.P., Bulloch, A.G. , Early evolutionary origin of the neurotrophin receptor family, EMBO J, vol. 17, no. 9, pp. 2534-2542. DOI
Haller, J., Millar, S., Kruk, M.R. , Mineralocorticoid receptor blockade inhibits aggressive behaviour in male rats, Stress, vol. 2, no. 3, pp. 201-207. DOI
Tensen, C.P., Cox, K.J., Burke, J.F., Leurs, R., van der Schors, R.C., Geraerts, W.P., Vreugdenhil, E., Heerikhuizen, H. , Molecular cloning and characterization of an invertebrate homologue of a neuropeptide Y receptor, Eur J Neurosci, vol. 10, no. 11, pp. 3409-3416. DOI
van Oers, H.J. , Maternal Deprivation: Implications for the ontogeny of the neural stress circuitry, LACDR, Medical Pharmacology, vol. PhD, Leiden, Leiden University, LACDR, Dept. Medical Pharmacology.
Della Paschoa, O.E., Kruk, M.R., Danhof, M. , Phamacokinetic-pharmacodynamic modelling of behavioural responses, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 229-236. DOI
Della Paschoa, O.E., Kruk, M.R., Hamstra, R., Voskuyl, R.A., Danhof, M. , Pharmacodynamic interaction between phenytoin and sodium valproate changes seizure thresholds and pattern, Br J Pharmacol, vol. 125, no. 5, pp. 997-1004. DOI
Kruk, M.R., Westphal, K.G., Van Erp, A.M.M., van Asperen, J., Cave, B.J., Slater, E., de Koning, J., Haller, J. , The hypothalamus: cross-roads of endocrine and behavioural regulation in grooming and aggression, Neurosci Biobehav Rev, vol. 23, no. 2, pp. 163-177. DOI
Tensen, C.P., Cox, K.J., Smit, A.B., van der Schors, R.C., Meyerhof, W., Richter, D., Planta, R.J., Hermann, P.M., van Minnen, J., Geraerts, W.P., Knol, J.C., Burke, J.F., Vreugdenhil, E., van Heerikhuizen, H. , The lymnaea cardioexcitatory peptide (LyCEP) receptor: a G-protein-coupled receptor for a novel member of the RFamide neuropeptide family, J Neurosci, vol. 18, no. 23, pp. 9812-9821.
1997
Karst, H., de Kloet, E.R., Joels, M. , Effect of ORG 34116, a corticosteroid receptor antagonist, on hippocampal Ca2+ currents, Eur J Pharmacol, vol. 339, no. 1, pp. 17-26. DOI
Workel, J.O., Oitzl, M.S., Ledeboer, A., De Kloet, E.R. , The Brown Norway rat displays enhanced stress-induced ACTH reactivity at day 18 after 24-h maternal deprivation at day 3, Brain Res Dev Brain Res, vol. 103, no. 2, pp. 199-203. DOI
Karst, H., Bosma, A., Hendriksen, E., Kamphuis, W., de Kloet, E.R., Joels, M. , Effect of adrenalectomy in kindled rats, Neuroendocrinology, vol. 66, no. 5, pp. 348-359. DOI
van Haarst, A.D., Oitzl, M.S., de Kloet, E.R. , Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus, Neurochem Res, vol. 22, no. 11, pp. 1323-1328. DOI
Oitzl, M.S., de Kloet, E.R., Joels, M., Schmid, W., Cole, T.J. , Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption, Eur J Neurosci, vol. 9, no. 11, pp. 2284-2296. DOI
Bhatnagar, M., Cintra, A., Chadi, G., Lindberg, J., Oitzl, M.S., De Kloet, E.R., Moller, A., Agnati, L.F., Fuxe, K. , Neurochemical changes in the hippocampus of the brown Norway rat during aging, Neurobiol Aging, vol. 18, no. 3, pp. 319-327. DOI
Schaaf, M.J., Hoetelmans, R.W., de Kloet, E.R., Vreugdenhil, E. , Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus, J Neurosci Res, vol. 48, no. 4, pp. 334-41. DOI
Oitzl, M.S., Mulder, M., Lucassen, P.J., Havekes, L.M., Grootendorst, J., de Kloet, E.R. , Severe learning deficits in apolipoprotein E-knockout mice in a water maze task, Brain Res, vol. 752, no. 1-2, pp. 189-196. DOI
Meijer, O.C., Cole, T.J., Schmid, W., Schutz, G., Joels, M., De Kloet, E.R. , Regulation of hippocampal 5-HT1A receptor mRNA and binding in transgenic mice with a targeted disruption of the glucocorticoid receptor, Brain Res Mol Brain Res, vol. 46, no. 1-2, pp. 290-296. DOI
Krugers, H.J., Mulder, M., Korf, J., Havekes, L., de Kloet, E.R., Joels, M. , Altered synaptic plasticity in hippocampal CA1 area of apolipoprotein E deficient mice, Neuroreport, vol. 8, no. 11, pp. 2505-2510.
Szuran, T.F., van Haarst, A.D., de Kloet, E.R., Pliska, V. , Steroid receptors in the rat hippocampus: a note to the methodology of their binding assay, J Recept Signal Transduct Res, vol. 17, no. 1-3, pp. 337-354. DOI
Ferrini, M.G., Grillo, C.A., Piroli, G., de Kloet, E.R., De Nicola, A.F. , Sex difference in glucocorticoid regulation of vasopressin mRNA in the paraventricular hypothalamic nucleus, Cell Mol Neurobiol, vol. 17, no. 6, pp. 671-686. DOI
Nicot, A., Rowe, W.B., De Kloet, E.R., Betancur, C., Jessop, D.S., Lightman, S.L., Quirion, R., Rostene, W., Berod, A. , Endogenous neurotensin regulates hypothalamic-pituitary-adrenal axis activity and peptidergic neurons in the rat hypothalamic paraventricular nucleus, J Neuroendocrinol, vol. 9, no. 4, pp. 263-269. DOI
Oitzl, M.S., van Haarst, A.D., de Kloet, E.R. , Behavioral and neuroendocrine responses controlled by the concerted action of central mineralocorticoid (MRS) and glucocorticoid receptors (GRS), Psychoneuroendocrinology, vol. 22, no. Suppl-1, pp. S87-S93. DOI
Cox, K.J., Tensen, C.P., van der Schors, R.C., Li, K.W., van Heerikhuizen, H., Vreugdenhil, E., Geraerts, W.P., Burke, J.F. , Cloning, characterization, and expression of a G-protein-coupled receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide, PSFHSWSamide, as its endogenous ligand, J Neurosci, vol. 17, no. 4, pp. 1197-1205.
Gerhardt, C.C., Lodder, H.C., Vincent, M., Bakker, R.A., Planta, R.J., Vreugdenhil, E., Kits, K.S., van Heerikhuizen, H. , Cloning and expression of a complementary DNA encoding a molluscan octopamine receptor that couples to chloride channels in HEK293 cells, J Biol Chem, vol. 272, no. 10, pp. 6201-6207. DOI
Joels, M., Karten, Y., Hesen, W., de Kloet, E.R. , Corticosteroid effects on electrical properties of brain cells: temporal aspects and role of antiglucocorticoids, Psychoneuroendocrinology, vol. 22 Suppl 1, pp. S81-S86. DOI
Wilckens, T., de Rijk, R.H. , Glucocorticoids and immune function: unknown dimensions and new frontiers, Immunol Today, vol. 18, no. 9, pp. 418-424. DOI
Gerhardt, C.C., Bakker, R.A., Piek, G.J., Planta, R.J., Vreugdenhil, E., Leysen, J.E., van Heerikhuizen, H. , Molecular cloning and pharmacological characterization of a molluscan octopamine receptor, Mol Pharmacol, vol. 51, no. 2, pp. 293-300.
Smith, M.A., Kim, S.Y., van Oers, H.J., Levine, S. , Maternal deprivation and stress induce immediate early genes in the infant rat brain, Endocrinology, vol. 138, no. 11, pp. 4622-4628. DOI
Della Paschoa, O.E., Kruk, M.R., Hamstra, R., Voskuyl, R.A., Danhof, M. , Seizure patterns in kindling and cortical stimulation models of experimental epilepsy, Brain Res, vol. 770, no. 1-2, pp. 221-227. DOI
1996
Vreugdenhil, E., de Jong, J., Schaaf, M.J., Meijer, O.C., Busscher, J., Vuijst, C., de Kloet, E.R. , Molecular dissection of corticosteroid action in the rat hippocampus. Application of the differential display techniques, J Mol Neurosci, vol. 7, no. 2, pp. 135-146. DOI
De Kloet, E.R., Korte, S.M., Rots, N.Y., Kruk, M.R. , Stress hormones, genotype, and brain organization. Implications for aggression, Ann N Y Acad Sci, vol. 794, pp. 179-91. DOI
Korte, S.M., Meijer, O.C., de Kloet, E.R., Buwalda, B., Keijser, J., Sluyter, F., van Oortmerssen, G., Bohus, B. , Enhanced 5-HT1A receptor expression in forebrain regions of aggressive house mice, Brain Res, vol. 736, no. 1-2, pp. 338-343. DOI
Hesen, W., Karst, H., Meijer, O.C., Cole, T.J., Schmid, W., de Kloet, E.R., Schutz, G., Joels, M. , Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption, J Neurosci, vol. 16, no. 21, pp. 6766-6774.
Korte-Bouws, G.A., Korte, S.M., De Kloet, E.R., Bohus, B. , Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis, J Neuroendocrinol, vol. 8, no. 11, pp. 877-881. DOI
van Haarst, A.D., Oitzl, M.S., Workel, J.O., de Kloet, E.R. , Chronic brain glucocorticoid receptor blockade enhances the rise in circadian and stress-induced pituitary-adrenal activity, Endocrinology, vol. 137, no. 11, pp. 4935-4943. DOI
Rots, N.Y., Cools, A.R., Oitzl, M.S., de Jong, J., Sutanto, W., de Kloet, E.R. , Divergent prolactin and pituitary-adrenal activity in rats selectively bred for different dopamine responsiveness, Endocrinology, vol. 137, no. 5, pp. 1678-1686. DOI
Korte, S.M., Korte-Bouws, G.A., Koob, G.F., De Kloet, E.R., Bohus, B. , Mineralocorticoid and glucocorticoid receptor antagonists in animal models of anxiety, Pharmacol Biochem Behav, vol. 54, no. 1, pp. 261-267. DOI
de Kloet, E.R., Rots, N.Y., Cools, A.R. , Brain-corticosteroid hormone dialogue: slow and persistent, Cell Mol Neurobiol, vol. 16, no. 3, pp. 345-356. DOI
Vreugdenhil, E., de Jong, J., Busscher, J.S., de Kloet, E.R. , Kainic acid-induced gene expression in the rat hippocampus is severely affected by adrenalectomy, Neurosci Lett, vol. 212, no. 2, pp. 75-78. DOI
Rots, N.Y., de Jong, J., Workel, J.O., Levine, S., Cools, A.R., De Kloet, E.R. , Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine, J Neuroendocrinol, vol. 8, no. 7, pp. 501-506. DOI
Korte, S.M., Buwalda, B., De Kloet, E.R., Bohus, B. , Adrenaline release by the 5-HT1A receptor agonist 8-OH-DPAT is partly responsible for pituitary activation, Eur J Pharmacol, vol. 309, no. 3, pp. 281-286. DOI
van Haarst, A.D., Welberg, L.A., Sutanto, W., Oitzl, M.S., de Kloet, E.R. , 11 beta-Hydroxysteroid dehydrogenase activity in the hippocampus: implications for in vivo corticosterone receptor binding and cell nuclear retention, J Neuroendocrinol, vol. 8, no. 8, pp. 595-600. DOI
Rots, N.Y., Workel, J., Oitzl, M.S., Berod, A., Rostene, W., Cools, A.R., De Kloet, E.R. , Development of divergence in dopamine responsiveness in genetically selected rat lines is preceded by changes in pituitary-adrenal activity, Brain Res Dev Brain Res, vol. 92, no. 2, pp. 164-171. DOI
Sutanto, W., Rosenfeld, P., de Kloet, E.R., Levine, S. , Long-term effects of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors, Brain Res Dev Brain Res, vol. 92, no. 2, pp. 156-163. DOI
Korte, S.M., De Kloet, E.R., Buwalda, B., Bouman, S.D., Bohus, B. , Antisense to the glucocorticoid receptor in hippocampal dentate gyrus reduces immobility in forced swim test, Eur J Pharmacol, vol. 301, no. 1-3, pp. 19-25. DOI
Beaulieu, J., Champagne, D.L., Drolet, G. , Enkephalin innervation of the paraventricular nucleus of the hypothalamus: distribution of fibers and origins of input, J Chem Neuroanat, vol. 10, no. 2, pp. 79-92. DOI
van Steensel, B., van Binnendijk, E.P., Hornsby, C.D., van der Voort, H.T., Krozowski, Z.S., de Kloet, E.R., van Driel, R. , Partial colocalization of glucocorticoid and mineralocorticoid receptors in discrete compartments in nuclei of rat hippocampus neurons, J Cell Sci, vol. 109, no. 4, pp. 787-792.
De Kloet, E.R., Joels, M. , Corticosteroid hormones in neuroprotection and brain damage, Current Opinion in Endocrinology & Diabetes, vol. 3, no. 2, pp. 184-192.
Semina, E.V., Reiter, R., Leysens, N.J., Alward, W.L., Small, K.W., Datson, N.A., Siegel-Bartelt, J., Bierke-Nelson, D., Bitoun, P., Zabel, B.U., Carey, J.C., Murray, J.C. , Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome, Nat Genet, vol. 14, no. 4, pp. 392-399. DOI
van Kesteren, R.E., Tensen, C.P., Smit, A.B., van Minnen, J., Kolakowski, L.F., Meyerhof, W., Richter, D., van Heerikhuizen, H., Vreugdenhil, E., Geraerts, W.P. , Co-evolution of ligand-receptor pairs in the vasopressin/oxytocin superfamily of bioactive peptides, J Biol Chem, vol. 271, no. 7, pp. 3619-3626. DOI
Gerhardt, C.C., Leysen, J.E., Planta, R.J., Vreugdenhil, E., van Heerikhuizen, H. , Functional characterisation of a 5-HT2 receptor cDNA cloned from Lymnaea stagnalis, Eur J Pharmacol, vol. 311, no. 2-3, pp. 249-258. DOI
Sibug, R.M., Kuppers, E., Beyer, C., Maxson, S.C., Pilgrim, C., Reisert, I , Genotype-dependent sex differentiation of dopaminergic neurons in primary cultures of embryonic mouse brain, Brain Res Dev Brain Res, vol. 93, no. 1-2, pp. 136-142. DOI
Molewijk, H.E., Hartog, K., van der Poel, A.M., Mos, J., Olivier, B. , Reduction of guinea pig pup isolation calls by anxiolytic and antidepressant drugs, Psychopharmacology, vol. 128, no. 1, pp. 31-38. DOI
Vazquez, D.M., van Oers, H.J., Levine, S., Akil, H. , Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat, Brain Res, vol. 731, no. 1-2, pp. 79-90. DOI
Datson, N.A., van de Vosse, E., Dauwerse, H.G., Bout, M., van Ommen, G.J., den Dunnen, J.T. , Scanning for genes in large genomic regions: cosmid-based exon trapping of multiple exons in a single product, Nucleic Acids Res, vol. 24, no. 6, pp. 1105-1111. DOI
1995
van Steensel, B., Brink, M., van der Meulen, K., van Binnendijk, E.P., Wansink, D.G., de Jong, L., de Kloet, E.R., van Driel, R. , Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus, J Cell Sci, vol. 108, no. 9, pp. 3003-3011.
de Kloet, E.R. , Steroids, stability and stress, Front Neuroendocrinol, vol. 16, no. 4, pp. 416-425. DOI
Sutanto, W., de Kloet, E.R. , Corticosteroid receptor antagonists: a current perspective, Pharm World Sci, vol. 17, no. 2, pp. 31-41. DOI
Van Eekelen, J.A., Oitzl, M.S., De Kloet, E.R. , Adrenocortical hyporesponsiveness and glucocorticoid feedback resistance in old male brown Norway rats, J Gerontol A Biol Sci Med Sci, vol. 50A, no. 2, pp. B83-B89. DOI
Joels, M., Hesen, W., de Kloet, E.R. , Long-term control of neuronal excitability by corticosteroid hormones, J Steroid Biochem Mol Biol, vol. 53, no. 1-6, pp. 315-323. DOI
Korte, S.M., Buwalda, B., Meijer, O.C., De Kloet, E.R., Bohus, B. , Socially defeated male rats display a blunted adrenocortical response to a low dose of 8-OH-DPAT, Eur J Pharmacol, vol. 272, no. 1, pp. 45-50. DOI
Rots, N.Y., Cools, A.R., de Jong, J., De Kloet, E.R. , Corticosteroid feedback resistance in rats genetically selected for increased dopamine responsiveness, J Neuroendocrinol, vol. 7, no. 2, pp. 153-161. DOI
Vallee, S.M., Grillo, C.A., Gonzalez, S., Cosen-Binker, L., de Kloet, E.R., McEwen, B.S., De Nicola, A.F. , Further studies in deoxycorticosterone acetate treated rats: brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake, Neuroendocrinology, vol. 61, no. 2, pp. 117-124. DOI
Carey, M.P., Deterd, C.H., de Koning, J., Helmerhorst, F., de Kloet, E.R. , The influence of ovarian steroids on hypothalamic-pituitary-adrenal regulation in the female rat, J Endocrinol, vol. 144, no. 2, pp. 311-321. DOI
Bressers, W.M., Kruk, M.R., Van Erp, A.M.M., Willekens-Bramer, D.C., Haccou, P., Meelis, E. , A time-structured analysis of hypothalamically induced increases in self-grooming and activity in the rat, Behav Neurosci, vol. 109, no. 6, pp. 1158-1171. DOI
Knol, J.C., van der Slik, A.R., van Kesteren, E.R., Planta, R.J., van Heerikhuizen, H., Vreugdenhil, E. , A novel G protein alpha subunit containing atypical guanine nucleotide-binding domains is differentially expressed in a molluscan nervous system, J Biol Chem, vol. 270, no. 32, pp. 18804-18808. DOI
Korte, S.M., de Boer, S.F., de Kloet, E.R., Bohus, B. , Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze, Psychoneuroendocrinology, vol. 20, no. 4, pp. 385-394. DOI
Suchecki, D., Nelson, D.Y., van Oers, H.J., Levine, S. , Activation and inhibition of the hypothalamic-pituitary-adrenal axis of the neonatal rat: effects of maternal deprivation, Psychoneuroendocrinology, vol. 20, no. 2, pp. 169-182. DOI
van Kesteren, R.E., Tensen, C.P., Smit, A.B., van Minnen, J., van Soest, P.F., Kits, K.S., Meyerhof, W., Richter, D., van Heerikhuizen, H., Vreugdenhil, E. , A novel G protein-coupled receptor mediating both vasopressin- and oxytocin-like functions of Lys-conopressin in Lymnaea stagnalis, Neuron, vol. 15, no. 4, pp. 897-908. DOI
Knol, J.C., Ramnatsingh, S., van Kesteren, E.R., van Minnen, J., Planta, R.J., van Heerikhuizen, H., Vreugdenhil, E. , Cloning of a molluscan G protein alpha subunit of the Gq class which is expressed differentially in identified neurons, Eur J Biochem, vol. 230, no. 1, pp. 193-199. DOI
Molewijk, H.E., van der Poel, A.M., Mos, J., Van der Heyden, J.A.M., Olivier, B. , Conditioned ultrasonic distress vocalizations in adult male rats as a behavioural paradigm for screening anti-panic drugs, Psychopharmacology, vol. 117, no. 1, pp. 32-40. DOI
Roovers, E., Vincent, M.E., van Kesteren, E.R., Geraerts, W.P., Planta, R.J., Vreugdenhil, E., van Heerikhuizen, H. , Characterization of a putative molluscan insulin-related peptide receptor, Gene, vol. 162, no. 2, pp. 181-188. DOI
Noach, E.L. , Ethical assessment of biomedical experiments in The Netherlands, Verh K Acad Geneeskd Belg, vol. 57, no. 3, pp. 158-179; discussion 179-182.
Van Erp, A.M.M., Kruk, M.R., Veening, J.G., Roeling, T.A.P., Meelis, W. , Neuronal substrate of electrically induced grooming in the PVH of the rat: involvement of oxytocinergic systems?, Physiol Behav, vol. 57, no. 5, pp. 881-885. DOI
Van Erp, A.M.M., Kruk, M.R., Willekens-Bramer, D.C., Fermont, P.C., Nijsen, M.J. , PVH lesions do not inhibit stressor-induced grooming in the rat, Physiol Behav, vol. 57, no. 5, pp. 887-892. DOI
Drolet, G., Beaulieu, J., Mansi, J.A., Champagne, D.L., Laforest, S. , Relationship between exposure to stress and development of hypertension, Ann Endocrinol (Paris), vol. 56, no. 3, pp. 187-191.
Rostene, W., Sarrieau, A., Nicot, A., Scarceriaux, V., Betancur, C., Gully, D., Meaney, M., Rowe, W., De Kloet, E.R., Pelaprat, D. , Steroid effects on brain functions: an example of the action of glucocorticoids on central dopaminergic and neurotensinergic systems, J Psychiatry Neurosci, vol. 20, no. 5, pp. 349-356.
Visser, G.M., Krugers, H.J., Luurtsema, G., Van Waarde, A., Elsinga, P.H., De Kloet, E.R., Groen, M.B., Bohus, B., Go, K.G., Paans, A.M.J., Korf, J., Vaalburg, W. , Synthesis and Organ Distribution of [F-18]Fluoro-Org-6141 in the Rat - A Potential Glucocorticoid Receptor-Ligand for Positron Emission Tomography, Nuclear Medicine and Biology, vol. 22, no. 7, pp. 915-920. DOI
Bressers, W.M., Kruk, M.R., Van Erp, A.M.M., Willekens-Bramer, D.C., Haccou, P., Meelis, E. , Time structure of self-grooming in the rat: self-facilitation and effects of hypothalamic stimulation and neuropeptides, Behav Neurosci, vol. 109, no. 5, pp. 955-964. DOI
Molewijk, H.E., van der Poel, A.M., Olivier, B. , The ambivalent behaviour "stretched approach posture" in the rat as a paradigm to characterize anxiolytic drugs, Psychopharmacology, vol. 121, no. 1, pp. 81-90. DOI
1994
Sutanto, W., de Kloet, E.R. , The use of various animal models in the study of stress and stress-related phenomena, Lab Anim, vol. 28, no. 4, pp. 293-306. DOI
Meijer, O.C., Oitzl, M.S., de Kloet, E.R. , Adrenalectomy leads to a different responsiveness to 8-OH-DPAT in a water-maze learning task, Ann N Y Acad Sci, vol. 746, pp. 408-10. DOI
de Kloet, E.R., Rots, N.Y., van den Berg, D.T., Oitzl, M.S. , Brain mineralocorticoid receptor function, Ann N Y Acad Sci, vol. 746, pp. 8-20; discussion 20-1, 64-7. DOI
Hornsby, C.D., de Kloet, E.R. , Dexamethasone does not prevent apoptosis in the hippocampus of the rat, Ann N Y Acad Sci, vol. 746, pp. 470-2. DOI
Carey, M.P., de Kloet, E.R. , Interaction of progesterone with the hippocampal mineralocorticoid receptor, Ann N Y Acad Sci, vol. 746, pp. 434-7. DOI
Korte, S.M., Buwalda, B., de Kloet, E.R., Bohus, B. , Social defeat impairs plasma corticosterone response to the 5-HT1A agonist 8-OH-DPAT in the rat, Ann N Y Acad Sci, vol. 746, pp. 426-8. DOI
Cirulli, F., van Oers, H., De Kloet, E.R., Levine, S. , Differential influence of corticosterone and dexamethasone on schedule-induced polydipsia in adrenalectomized rats, Behav Brain Res, vol. 65, no. 1, pp. 33-9. DOI
Schobitz, B., De Kloet, E.R., Holsboer, F. , Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain, Prog Neurobiol, vol. 44, no. 4, pp. 397-432. DOI
Nicot, A., Berod, A., Gully, D., Rowe, W., Quirion, R., de Kloet, E.R., Rostene, W. , Blockade of neurotensin binding in the rat hypothalamus and of the central action of neurotensin on the hypothalamic-pituitary-adrenal axis with non-peptide receptor antagonists, Neuroendocrinology, vol. 59, no. 6, pp. 572-578. DOI
Joels, M., Hesen, W., Karst, H., de Kloet, E.R. , Steroids and electrical activity in the brain, J Steroid Biochem Mol Biol, vol. 49, no. 4-6, pp. 391-398. DOI
Oitzl, M.S., Fluttert, M.F., de Kloet, E.R. , The effect of corticosterone on reactivity to spatial novelty is mediated by central mineralocorticosteroid receptors, Eur J Neurosci, vol. 6, no. 7, pp. 1072-1079. DOI
Meijer, O.C., de Kloet, E.R. , Corticosterone suppresses the expression of 5-HT1A receptor mRNA in rat dentate gyrus, Eur J Pharmacol, vol. 266, no. 3, pp. 255-261.
Van den Berg, D.T., de Kloet, E.R., de Jong, W. , Central effects of mineralocorticoid antagonist RU-28318 on blood pressure of DOCA-salt hypertensive rats, Am J Physiol Endocrinol Metab, vol. 267, no. 6, pp. E927-E933.
Wiegers, G.J., Reul, J.M., Holsboer, F., de Kloet, E.R. , Enhancement of rat splenic lymphocyte mitogenesis after short term preexposure to corticosteroids in vitro, Endocrinology, vol. 135, no. 6, pp. 2351-2357. DOI
Van den Berg, D.T., de Jong, W., de Kloet, E.R. , Mineralocorticoid antagonist inhibits stress-induced blood pressure response after repeated daily warming, Am J Physiol Endocrinol Metab, vol. 267, no. 6, pp. E921-E926.
Schobitz, B., Sutanto, W., Carey, M.P., Holsboer, F., de Kloet, E.R. , Endotoxin and interleukin 1 decrease the affinity of hippocampal mineralocorticoid (type I) receptor in parallel to activation of the hypothalamic-pituitary-adrenal axis, Neuroendocrinology, vol. 60, no. 2, pp. 124-133. DOI
Schobitz, B., Holsboer, F., Sutanto, W., Gross, G., Schonbaum, E., de Kloet, E.R. , Corticosterone modulates interleukin-evoked fever in the rat, Neuroendocrinology, vol. 59, no. 4, pp. 387-395. DOI
Knol, J.C., Roovers, E., van Kesteren, E.R., Planta, R.J., Vreugdenhil, E., van Heerikhuizen, H. , A G-protein beta subunit that is expressed in the central nervous system of the mollusc Lymnaea stagnalis identified through cDNA cloning, Biochim Biophys Acta, vol. 1222, no. 1, pp. 129-133. DOI
Noach, E.L. , Appetite regulation by serotoninergic mechanisms and effects of d-fenfluramine, Netherlands Journal of Medicine, vol. 45, no. 3, pp. 123-133.
Tensen, C.P., van Kesteren, E.R., Planta, R.J., Cox, K.J., Burke, J.F., van Heerikhuizen, H., Vreugdenhil, E. , A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction, PNAS, vol. 91, no. 11, pp. 4816-4820.
Tilders, F.J., de Rijk, R.H., Van Dam, A.M., Vincent, V.A., Schotanus, K., Persoons, J.H. , Activation of the hypothalamus-pituitary-adrenal axis by bacterial endotoxins: routes and intermediate signals, Psychoneuroendocrinology, vol. 19, no. 2, pp. 209-232. DOI
Cintra, A., Lindberg, J., Chadi, G., Tinner, B., Moller, A., Gustafsson, J.A., De Kloet, E.R., Oitzl, M.S., Nishikawa, K., Agnati, L.F. , Basic fibroblast growth factor and steroid receptors in the aging hippocampus of the brown Norway rat: immunocytochemical analysis in combination with stereology, Neurochem Int, vol. 25, no. 1, pp. 39-45. DOI
De Kloet, E.R., Oitzl, M.S., Schobitz, B. , Cytokines and the brain corticosteroid receptor balance: relevance to pathophysiology of neuroendocrine-immune communication, Psychoneuroendocrinology, vol. 19, no. 2, pp. 121-134. DOI
de Rijk, R.H., Sternberg, E.M. , Corticosteroid action and neuroendocrine-immune interactions, Ann N Y Acad Sci, vol. 746, pp. 33-41. DOI
Jongen-Relo, A.L., Docter, G.J., Jonker, A.J., Vreugdenhil, E., Groenewegen, H.J., Voorn, P. , Differential effects of dopamine depletion on the binding and mRNA levels of dopamine receptors in the shell and core of the rat nucleus accumbens, Brain Res Mol Brain Res, vol. 25, no. 3-4, pp. 333-343. DOI
Roeling, T.A.P., Veening, J.G., Kruk, M.R., Peters, J.P., Vermelis, M.E., Nieuwenhuys, R. , Efferent connections of the hypothalamic "aggression area" in the rat, Neuroscience, vol. 59, no. 4, pp. 1001-1024. DOI
de Rijk, R.H., Berkenbosch, F. , Hypothermia to endotoxin involves the cytokine tumor necrosis factor and the neuropeptide vasopressin in rats, Am J Physiol Regul Integr Comp Physiol, vol. 266, no. 1, pp. R9-R14.
de Rijk, R.H., Van Kampen, M., Van Rooijen, N., Berkenbosch, F. , Hypothermia to endotoxin involves reduced thermogenesis, macrophage-dependent mechanisms, and prostaglandins, Am J Physiol Regul Integr Comp Physiol, vol. 266, no. 1, pp. R1-R8.
de Rijk, R.H., Boelen, A., Tilders, F.J., Berkenbosch, F. , Induction of plasma interleukin-6 by circulating adrenaline in the rat, Psychoneuroendocrinology, vol. 19, no. 2, pp. 155-163. DOI
de Groot, A.J., Jansen, J.G., van Valkenburg, C.F.M., van Zeeland, A.A. , Molecular dosimetry of 7-alkyl- and O6-alkylguanine in DNA by electrochemical detection, Mutat Res, vol. 307, no. 1, pp. 61-66. DOI
Burges, J., Vincent, A., Molenaar, P.C., Newsom-Davis, J., Peers, C., Wray, D. , Passive transfer of seronegative myasthenia gravis to mice, Muscle Nerve, vol. 17, no. 12, pp. 1393-1400. DOI
Van Kempen, G.T.H., Molenaar, P.C., Slater, C.R. , Release and synthesis of acetylcholine at ectopic neuromuscular junctions in the rat, J Physiol, vol. 478 ( Pt 2, no. 2, pp. 229-238.
Madsen, C.S., Brooks, J.E., De Kloet, E., de Kloet, S.R. , Sequence conservation of an avian centromeric repeated DNA component, Genome, vol. 37, no. 3, pp. 351-355. DOI
Plomp, J.J., Van Kempen, G.T.H., Molenaar, P.C. , The upregulation of acetylcholine release at endplates of alpha-bungarotoxin-treated rats: its dependency on calcium, J Physiol, vol. 478 ( Pt 1, pp. 125-136.
1993
Joels, M., de Kloet, E.R. , Corticosteroid actions on amino acid-mediated transmission in rat CA1 hippocampal cells, J Neurosci, vol. 13, no. 9, pp. 4082-90.
Schobitz, B., de Kloet, E.R., Sutanto, W., Holsboer, F. , Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain, Eur J Neurosci, vol. 5, no. 11, pp. 1426-1435. DOI
Oitzl, M.S., van Oers, H., Schobitz, B., de Kloet, E.R. , Interleukin-1 beta, but not interleukin-6, impairs spatial navigation learning, Brain Res, vol. 613, no. 1, pp. 160-163. DOI
van Dijken, H.H., de Goeij, D.C., Sutanto, W., Mos, J., de Kloet, E.R., Tilders, F.J. , Short inescapable stress produces long-lasting changes in the brain-pituitary-adrenal axis of adult male rats, Neuroendocrinology, vol. 58, no. 1, pp. 57-64. DOI
Rothuizen, J., Reul, J.M., van Sluijs, F.J., Mol, J.A., Rijnberk, A., de Kloet, E.R. , Increased neuroendocrine reactivity and decreased brain mineralocorticoid receptor-binding capacity in aged dogs, Endocrinology, vol. 132, no. 1, pp. 161-168. DOI
de Kloet, E.R., Sutanto, W., van den Berg, D.T., Carey, M.P., van Haarst, A.D., Hornsby, C.D., Meijer, O.C., Rots, N.Y., Oitzl, M.S. , Brain mineralocorticoid receptor diversity: functional implications, J Steroid Biochem Mol Biol, vol. 47, no. 1-6, pp. 183-190. DOI
Wiegers, G.J., Croiset, G., Reul, J.M., Holsboer, F., de Kloet, E.R. , Differential effects of corticosteroids on rat peripheral blood T-lymphocyte mitogenesis in vivo and in vitro, Am J Physiol Endocrinol Metab, vol. 265, no. 6 Pt 1, pp. E825-E830.
de Kloet, E.R., Oitzl, M.S., Joels, M. , Functional implications of brain corticosteroid receptor diversity, Cell Mol Neurobiol, vol. 13, no. 4, pp. 433-455. DOI
Rosenfeld, P., van Eekelen, J.A., Levine, S., de Kloet, E.R. , Ontogeny of corticosteroid receptors in the brain, Cell Mol Neurobiol, vol. 13, no. 4, pp. 295-319. DOI
Schobitz, B., Van Den Dobbelsteen, M., Holsboer, F., Sutanto, W., De Kloet, E.R. , Regulation of interleukin 6 gene expression in rat, Endocrinology, vol. 132, no. 4, pp. 1569-1576. DOI
Oitzl, M.S., Josephy, M., Spruijt, B.M. , An ACTH/MSH(4-9) analog counteracts the behavioral effects of a mineralocorticoid receptor antagonist, Pharmacol Biochem Behav, vol. 44, no. 2, pp. 447-450. DOI
Roeling, T.A.P., Kruk, M.R., Schuurmans, R., Veening, J.G. , Behavioural responses of bicucculline methiodide injections into the ventral hypothalamus of freely moving, socially interacting rats, Brain Res, vol. 615, no. 1, pp. 121-127. DOI
Van Erp, A.M.M., Kruk, M.R., van Oers, H.J., Hemmers, N.M. , Differential effect of ACTH1-24 and alpha-MSH induced grooming in the paraventricular nucleus of the hypothalamus, Brain Res, vol. 603, no. 2, pp. 296-301. DOI
Molenaar, P.C., Biewenga, J.E., Van Kempen, G.T.H., De Priester, J.A. , Effect of ephedrine on muscle weakness in a model of myasthenia gravis in rats, Neuropharmacology, vol. 32, no. 4, pp. 373-376. DOI
Molenaar, P.C., Van Kempen, G.T.H. , Effect of diazepam on muscle weakness in a model of myasthenia gravis in rats, J Neural Transm, vol. 93, no. 3, pp. 181-185. DOI
de Rijk, R.H., Strijbos, P.J., Van Rooijen, N., Rothwell, N.J., Berkenbosch, F. , Fever and thermogenesis in response to bacterial endotoxin involve macrophage-dependent mechanisms in rats, Am J Physiol Regul Integr Comp Physiol, vol. 265, no. 5, pp. R1179-R1183.
Van Erp, A.M.M., Kruk, M.R., Semple, D.M., Verbeet, D.W. , Initiation of self-grooming in resting rats by local PVH infusion of oxytocin but not alpha-MSH, Brain Res, vol. 607, no. 1-2, pp. 108-112. DOI
Molenaar, G.J., Lugard-Kok, C., Meloen, R.H., Oonk, R.B., de Koning, J., Wensing, C.J. , Lesions in the hypothalamus after active immunisation against GnRH in the pig, J Neuroimmunol, vol. 48, no. 1, pp. 1-11. DOI
Olivier, B., Bosch, L., Van Hest, A., Van der Heyden, J., Mos, J., van der Poel, A.M., Schipper, J., Tulp, M. , Preclinical evidence on the psychotropic profile of fluvoxamine, Pharmacopsychiatry, vol. 26 Suppl 1, pp. 2-9. DOI
Van Erp, A.M.M., Kruk, M.R., Meelis, W., Veening, J.G. , Periaqueductal gray lesions do not affect grooming, induced electrically in the hypothalamic paraventricular area in the rat, Behav Brain Res, vol. 59, no. 1-2, pp. 95-101. DOI
1992
Voorhuis, T.A., de Kloet, E.R. , Immunoreactive vasotocin in the zebra finch brain (Taeniopygia guttata), Brain Res Dev Brain Res, vol. 69, no. 1, pp. 1-10. DOI
Schobitz, B., Holsboer, F., Kikkert, R., Sutanto, W., De Kloet, E.R. , Peripheral and central regulation of IL-6 gene expression in endotoxin-treated rats, Endocr Regul, vol. 26, no. 3, pp. 103-109.
Schobitz, B., Voorhuis, D.A., De Kloet, E.R. , Localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain, Neurosci Lett, vol. 136, no. 2, pp. 189-192. DOI
Brink, M., Humbel, B.M., De Kloet, E.R., Van Driel, R. , The unliganded glucocorticoid receptor is localized in the nucleus, not in the cytoplasm, Endocrinology, vol. 130, no. 6, pp. 3575-3581. DOI
van Eekelen, J.A., Rots, N.Y., Sutanto, W., de Kloet, E.R. , The effect of aging on stress responsiveness and central corticosteroid receptors in the brown Norway rat, Neurobiol Aging, vol. 13, no. 1, pp. 159-170. DOI
Joels, M., de Kloet, E.R. , Control of neuronal excitability by corticosteroid hormones, Trends Neurosci, vol. 15, no. 1, pp. 25-30. DOI
Oitzl, M.S., de Kloet, E.R. , Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning, Behav Neurosci, vol. 106, no. 1, pp. 62-71. DOI
Van der Krogt, J.A., Pauwels, E.K., Van Doremalen, P.A., Wijnhoven, G., Reiffers, S., van Valkenburg, C.F.M., Buruma, O.J. , 4-[123I]iodospiperone as a ligand for dopamine DA receptors: in vitro and in vivo experiments in a rat model, Int J Rad Appl Instrum B, vol. 19, no. 7, pp. 759-763. DOI
Plomp, J.J., Van Kempen, G.T.H., Molenaar, P.C. , Adaptation of quantal content to decreased postsynaptic sensitivity at single endplates in alpha-bungarotoxin-treated rats, J Physiol, vol. 458, no. 1, pp. 487-499.
Sutanto, W., Oitzl, M.S., Rots, N.Y., Schobitz, B., Van den Berg, D.T.W.M., van Dijken, H.H., Mos, J., Cools, A.R., Tilders, F.J., Koolhaas, J.M., De Kloet, E.R. , Corticosteroid receptor plasticity in the central nervous system of various rat models, Endocr Regul, vol. 26, no. 3, pp. 111-118.
Van Eekelen, J.A., De Kloet, E.R. , Co-localization of brain corticosteroid receptors in the rat hippocampus, Prog Histochem Cytochem, vol. 26, no. 1-4, pp. 250-258.
de Rijk, R.H., Berkenbosch, F. , Development and application of a radioimmunoassay to detect interleukin-1 in rat peripheral circulation, Am J Physiol Endocrinol Metab, vol. 263, no. 6, pp. E1092-E1098.
Van Kempen, G.T.H., Molenaar, P.C. , Effect of estradiol and progesterone on muscle weight and acetylcholine receptors in "myasthenic" rats, J Neural Transm, vol. 87, no. 3, pp. 193-197. DOI
Westenend, P.J., Nooyen, Y.A., Van der Krogt, J.A., van Brummelen, P., Weening, J.J. , Functional and structural determinants of glomerulosclerosis in the fawn-hooded rat, Eur J Clin Invest, vol. 22, no. 6, pp. 391-395. DOI
Barnard, E.A., Bateson, A.N., Darlison, M.G., Glencorse, T.A., Harvey, R.J., Hicks, A.A., Lasham, A., Shingai, R., Usherwood, P.N., Vreugdenhil, E. , Genes for the GABAA receptor subunit types and their expression, Adv Biochem Psychopharmacol, vol. 47, pp. 17-27.
Knol, J.C., Weidemann, W., Planta, R.J., Vreugdenhil, E., van Heerikhuizen, H. , Molecular cloning of G protein alpha subunits from the central nervous system of the mollusc Lymnaea stagnalis, FEBS Lett, vol. 314, no. 3, pp. 215-219. DOI
Elands, J., de Kloet, E.R., de Wied, D. , Neurohypophyseal hormone receptors: relation to behavior, Prog Brain Res, vol. 91, pp. 459-464. DOI
Burbach, J.P., Meijer, O.C. , The structure of neuropeptide receptors, Eur J Pharmacol, vol. 227, no. 1, pp. 1-18.
de Rijk, R.H., Van Rooijen, N., Berkenbosch, F. , The role of macrophages in the hypothalamic-pituitary-adrenal activation in response to endotoxin (LPS), Res Immunol, vol. 143, no. 2, pp. 224-229. DOI
Westenend, P.J., Nooyen, Y.A., Van der Krogt, J.A., van Brummelen, P., Weening, J.J. , The effect of a converting enzyme inhibitor upon renal damage in spontaneously hypertensive Fawn Hooded rats, J Hypertens, vol. 10, no. 5, pp. 417-422.
1991
Sijbesma, H., Schipper, J., Molewijk, H.E., Bosch, A. I, de Kloet, E.R. , 8-hydroxy-2-(di-N-propylamino)tetralin increases the activity of adenylate cyclase in the hippocampus of freely-moving rats, Neuropharmacology, vol. 30, no. 9, pp. 967-975. DOI
van Steensel, B., van Haarst, A.D., de Kloet, E.R., van Driel, R. , Binding of corticosteroid receptors to rat hippocampus nuclear matrix, FEBS Lett, vol. 292, no. 1-2, pp. 229-231. DOI
Eijgelshoven, M.H., De Kloet, E.R., Van den Berg, D.T., Van Giersbergen, P.L. , Activation of glucocorticoid receptors and the effect of naloxone during hemorrhagic hypotension, Eur J Pharmacol, vol. 205, no. 2, pp. 183-189. DOI
Sutanto, W., de Kloet, E.R. , Mineralocorticoid receptor ligands: biochemical, pharmacological, and clinical aspects, Med Res Rev, vol. 11, no. 6, pp. 617-639. DOI
Voorhuis, T.A., De Kloet, E.R., De Wied, D. , Ontogenetic and seasonal changes in immunoreactive vasotocin in the canary brain, Brain Res Dev Brain Res, vol. 61, no. 1, pp. 23-31. DOI
van Eekelen, J.A., Bohn, M.C., de Kloet, E.R. , Postnatal ontogeny of mineralocorticoid and glucocorticoid receptor gene expression in regions of the rat tel- and diencephalon, Brain Res Dev Brain Res, vol. 61, no. 1, pp. 33-43. DOI
Sijbesma, H., Schipper, J., de Kloet, E.R., Mos, J., van Aken, H., Olivier, B. , Postsynaptic 5-HT1 receptors and offensive aggression in rats: a combined behavioural and autoradiographic study with eltoprazine, Pharmacol Biochem Behav, vol. 38, no. 2, pp. 447-458. DOI
Voorhuis, T.A., De Kloet, E.R., De Wied, D. , Effect of a vasotocin analog on singing behavior in the canary, Horm Behav, vol. 25, no. 4, pp. 549-559. DOI
Sijbesma, H., Schipper, J., Cornelissen, J.C., de Kloet, E.R. , Species differences in the distribution of central 5-HT1 binding sites: a comparative autoradiographic study between rat and guinea pig, Brain Res, vol. 555, no. 2, pp. 295-304. DOI
Joels, M., Hesen, W., de Kloet, E.R. , Mineralocorticoid hormones suppress serotonin-induced hyperpolarization of rat hippocampal CA1 neurons, J Neurosci, vol. 11, no. 8, pp. 2288-2294.
Molenaar, P.C., Oen, B.S., Plomp, J.J., Van Kempen, G.T.H., Jennekens, F.G., Hesselmans, L.F. , A non-immunogenic myasthenia gravis model and its application in a study of transsynaptic regulation at the neuromuscular junction, Eur J Pharmacol, vol. 196, no. 1, pp. 93-101. DOI
Reul, J.M., Rothuizen, J., de Kloet, E.R. , Age-related changes in the dog hypothalamic-pituitary-adrenocortical system: neuroendocrine activity and corticosteroid receptors, J Steroid Biochem Mol Biol, vol. 40, no. 1-3, pp. 63-69. DOI
Rothuizen, J., Reul, J.M., Rijnberk, A., Mol, J.A., de Kloet, E.R. , Aging and the hypothalamus-pituitary-adrenocortical axis, with special reference to the dog, Acta Endocrinologica, vol. 125, no. 6, Suppl 1, pp. 73-76. DOI
van Dieten, J.A.M.J., de Koning, J., van Rees, G.P. , Autonomous FSH synthesis in vitro in anterior pituitary glands and grafts from female rats, J Endocrinol, vol. 129, no. 1, pp. 27-33. DOI
De Kloet, E.R. , Brain Corticosteroid Receptor Balance and Homeostatic Control, Front Neuroendocrinol, vol. 12, no. 2, pp. 95-164.
Roeling, T.A.P., Van Erp, A.M.M., Meelis, W., Kruk, M.R., Veening, J.G. , Behavioural effects of NMDA injected into the hypothalamic paraventricular nucleus of the rat, Brain Res, vol. 550, no. 2, pp. 220-224. DOI
Rotteveel, F.T.M., Verhoef, M.H.A.M., de Rijk, R.H., van den Berg, H., Wolvers, D.A.W., Berkenbosch, F. , Both interleukin-1 alpha and interleukin-1 beta are involved as accessory signals in primary antigen (tetanus toxoid) induced human T-cell activation, Cell Immunol, vol. 138, no. 1, pp. 245-250. DOI
van Eekelen, J.A., Rots, N.Y., Sutanto, W., Oitzl, M.S., de Kloet, E.R. , Brain corticosteroid receptor gene expression and neuroendocrine dynamics during aging, J Steroid Biochem Mol Biol, vol. 40, no. 4-6, pp. 679-683. DOI
Lasham, A., Vreugdenhil, E., Bateson, A.N., Barnard, E.A., Darlison, M.G. , Conserved organization of gamma-aminobutyric acidA receptor genes: cloning and analysis of the chicken beta 4-subunit gene, J Neurochem, vol. 57, no. 1, pp. 352-355. DOI
Sibug, R.M., Stumpf, W.E., Shughrue, P.J., Hochberg, R.B., Drews, U. , Distribution of estrogen target sites in the 2-day-old mouse forebrain and pituitary gland during the 'critical period' of sexual differentiation, Brain Res Dev Brain Res, vol. 61, no. 1, pp. 11-22. DOI
Joels, M., de Kloet, E.R. , Effect of corticosteroid hormones on electrical activity in rat hippocampus, J Steroid Biochem Mol Biol, vol. 40, no. 1-3, pp. 83-86. DOI
Kruk, M.R. , Ethology and pharmacology of hypothalamic aggression in the rat, Neurosci Biobehav Rev, vol. 15, no. 4, pp. 527-538. DOI
Van Erp, A.M.M., Kruk, M.R., Willekens-Bramer, D.C., Bressers, W.M., Roeling, T.A.P., Veening, J.G., Spruyt, B.M. , Grooming induced by intrahypothalamic injection of ACTH in the rat: comparison with grooming induced by intrahypothalamic electrical stimulation and i.c.v. injection of ACTH, Brain Res, vol. 538, no. 2, pp. 203-210. DOI
de Kloet, E.R., Joels, M., Oitzl, M.S., Sutanto, W. , Implication of brain corticosteroid receptor diversity for the adaptation syndrome concept, Methods Achiev Exp Pathol, vol. 14, pp. 104-132.
Berkenbosch, F., Wolvers, D.A., de Rijk, R.H. , Neuroendocrine and immunological mechanisms in stress-induced immunomodulation, J Steroid Biochem Mol Biol, vol. 40, no. 4-6, pp. 639-647. DOI
De Kloet, E.R., Sutanto, W., Rots, N., van Haarst, A., van den Berg, D.T., Oitzl, M.S., van Eekelen, A., Voorhuis, D. , Plasticity and function of brain corticosteroid receptors during aging, Acta Endocrinologica, vol. 125, no. 6, Suppl 1, pp. 65-72. DOI
de Rijk, R.H., Van Rooijen, N., Tilders, F.J., Besedovsky, H.O., Delrey, A., Berkenbosch, F. , Selective depletion of macrophages prevents pituitary-adrenal activation in response to subpyrogenic, but not to pyrogenic, doses of bacterial endotoxin in rats, Endocrinology, vol. 129, no. 1, pp. 330-338. DOI
Harvey, R.J., Vreugdenhil, E., Zaman, S.H., Bhandal, N.S., Usherwood, P.N., Barnard, E.A., Darlison, M.G. , Sequence of a functional invertebrate GABAA receptor subunit which can form a chimeric receptor with a vertebrate alpha subunit, EMBO J, vol. 10, no. 11, pp. 3239-3245.
De Bruijn, E.A., Driessen, O.M., Hermans, J. , The CMF-regimen. Toxicity patterns following stepwise combinations of cyclophosphamide, methotrexate and fluorouracil, Int J Cancer, vol. 48, no. 1, pp. 67-72. DOI
de Rijk, R.H., Berkenbosch, F. , The immune-hypothalamo-pituitary-adrenal axis and autoimmunity, Int J Neurosci, vol. 59, no. 1-3, pp. 91-100. DOI
1990
de Kloet, E.R., Reul, J.M., Sutanto, W. , Corticosteroids and the brain, J Steroid Biochem Mol Biol, vol. 37, no. 3, pp. 387-394. DOI
Elands, J., Resink, A., De Kloet, E.R. , Neurohypophyseal hormone receptors in the rat thymus, spleen, and lymphocytes, Endocrinology, vol. 126, no. 5, pp. 2703-2710. DOI
Rosenfeld, P., Sutanto, W., Levine, S., de Kloet, E.R. , Ontogeny of mineralocorticoid (type 1) receptors in brain and pituitary: an in vivo autoradiographical study, Brain Res Dev Brain Res, vol. 52, no. 1-2, pp. 57-62. DOI
van den Berg, D.T., de Kloet, E.R., van Dijken, H.H., de Jong, W. , Differential central effects of mineralocorticoid and glucocorticoid agonists and antagonists on blood pressure, Endocrinology, vol. 126, no. 1, pp. 118-124. DOI
Reul, J.M., de Kloet, E.R., van Sluijs, F.J., Rijnberk, A., Rothuizen, J. , Binding characteristics of mineralocorticoid and glucocorticoid receptors in dog brain and pituitary, Endocrinology, vol. 127, no. 2, pp. 907-915. DOI
Barnard, E.A., Darlinson, M.G., Harvey, R., Marshall, J., Moss, S.J., Sattelle, D.B., Smart, T.G., Vreugdenhil, E. , Cloned genes for ligand-operated ion channels and their expression in vitro, Adv Second Messenger Phosphoprotein Res, vol. 24, pp. 20-29.
Harvey, R.J., Vreugdenhil, E., Barnard, E.A., Darlison, M.G. , Cloning of genomic and cDNA sequences encoding an invertebrate gamma-aminobutyric acidA receptor subunit, Biochem Soc Trans, vol. 18, no. 3, pp. 438-439. DOI
Reul, J.M., Sutanto, W., van Eekelen, J.A., Rothuizen, J., de Kloet, E.R. , Central action of adrenal steroids during stress and adaptation, Adv Exp Med Biol, vol. 274, pp. 243-256.
Thesleff, S., Heilbronn, E., Molenaar, P.C., Engel, A.G. , Future prospects of cholinergic research on neuromuscular transmission, Prog Brain Res, vol. 84, pp. 171-174. DOI
Berkenbosch, F., de Rijk, R.H., Delrey, A., Besedovsky, H.O. , Neuroendocrinology of interleukin-1, Adv Exp Med Biol, vol. 274, pp. 303-314.
Oitzl, M.S., Hasenohrl, R.U., Huston, J.P. , Reinforcing effects of peripherally administered substance P and its C-terminal sequence pGlu6-SP6-11 in the rat, Psychopharmacology, vol. 100, no. 3, pp. 308-315. DOI
Molenaar, P.C. , Synaptic adaptation in diseases of the neuromuscular junction, Prog Brain Res, vol. 84, pp. 145-149. DOI
De Bruijn, E.A., Geng, Y., Hermans, J., Driessen, O.M. , The CMF-regimen. Modulation of cyclophosphamide uptake and clearance by methotrexate and fluorouracil, Int J Cancer, vol. 45, no. 5, pp. 935-939. DOI
van Valkenburg, C.F.M., Marani, E., Boon, M.E., Visser, P. , The use of microwave irradiation with low formalin concentrations to enhance the conversion of dopamine into norsalsolinol in rat brain: a pilot study, Histochem J, vol. 22, no. 6-7, pp. 353-357. DOI
1989
Joels, M., de Kloet, E.R. , Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus, Science, vol. 245, no. 4925, pp. 1502-1505. DOI
van den Berg, D.T., de Kloet, E.R., van Dijken, H.H., de Jong, W. , Brain corticosteroid receptors and regulation of arterial blood pressure, J Hypertens Suppl, vol. 7, no. 6, pp. S202-S203.
Ratka, A., Sutanto, W., Bloemers, M., de Kloet, E.R. , On the role of brain mineralocorticoid (type I) and glucocorticoid (type II) receptors in neuroendocrine regulation, Neuroendocrinology, vol. 50, no. 2, pp. 117-123. DOI
Emonds, A.J., de Vos, D. , Analysis of mucin as raw material and in a saliva substitute by isotachophoresis, Pharm Weekbl Sci, vol. 11, no. 2, pp. 61-63. DOI
Molenaar, P.C. , Acetylcholine compartments in skeletal muscle, Cell Biol Int Rep, vol. 13, no. 12, pp. 1077-1084. DOI
van den Dungen, H.M., van Dieten, J.A.M.J., Tilders, F.J., van Rees, G.P., Schoemaker, J. , Administration of a GnRH-antagonist to immature rats affects subsequent female and male pubertal development differently, Acta Endocrinologica, vol. 120, no. 6, pp. 778-784. DOI
Hasenöhrl, R.U., Oitzl, M.S., Huston, J.P. , Conditioned place preference in the corral: a procedure for measuring reinforcing properties of drugs, J Neurosci Methods, vol. 30, no. 2, pp. 141-146. DOI
Dirks, R.W., Raap, A.K., van Minnen, J., Vreugdenhil, E., Smit, A.B., Van der Ploeg, M. , Detection of mRNA molecules coding for neuropeptide hormones of the pond snail Lymnaea stagnalis by radioactive and non-radioactive in situ hybridization: a model study for mRNA detection, J Histochem Cytochem, vol. 37, no. 1, pp. 7-14.
Molenaar, P.C., Polak, R.L. , Effect of potassium propionate on free and bound acetylcholine in frog muscle, Brain Res, vol. 477, no. 1-2, pp. 109-117. DOI
van den Dungen, H.M., Dijkstra, H., Hiehle, M.A., van Rees, G.P., Schoemaker, J. , Effects of LHRH antagonist administration to immature male rats on sexual development, Physiol Behav, vol. 46, no. 5, pp. 779-785. DOI
van Minnen, J., Dirks, R.W., Vreugdenhil, E., van Diepen, J. , Expression of the egg-laying hormone genes in peripheral neurons and exocrine cells in the reproductive tract of the mollusc Lymnaea stagnalis, Neuroscience, vol. 33, no. 1, pp. 35-46. DOI
Lammers, J.H.C.M., van der Noordaa, J., Kruk, M.R., Meelis, W., van der Poel, A.M. , Interactions between simultaneously activated behavioral systems in the rat, Behav Neurosci, vol. 103, no. 4, pp. 784-789. DOI
Driessen, O.M., Hamelink, R., Hermans, J., Franken, H., Emonds, A.J., Davelaar, J. , Plasma spermidine and putrescine as markers of cancer management, Methods Find Exp Clin Pharmacol, vol. 11, no. 1, pp. 11-16.
Ceccarelli, B., Molenaar, P.C., Oen, B.S., Polak, R.L., Torri-Tarelli, F., van Kempen, G.T. , The effect of anions on bound acetylcholine in frog sartorius muscle, J Physiol, vol. 408, no. 1, pp. 233-249.
van der Poel, A.M., Noach, E.J.K., Miczek, K.A. , Temporal patterning of ultrasonic distress calls in the adult rat: effects of morphine and benzodiazepines, Psychopharmacology, vol. 97, no. 2, pp. 147-148. DOI
1988
Van Eekelen, J.A., Jiang, W., De Kloet, E.R., Bohn, M.C. , Distribution of the mineralocorticoid and the glucocorticoid receptor mRNAs in the rat hippocampus, J Neurosci Res, vol. 21, no. 1, pp. 88-94. DOI
Edwards, C.R., Stewart, P.M., Burt, D., Brett, L., McIntyre, M.A., Sutanto, W.S., de Kloet, E.R., Monder, C. , Localisation of 11 beta-hydroxysteroid dehydrogenase--tissue specific protector of the mineralocorticoid receptor, Lancet, vol. 2, no. 8618, pp. 986-989. DOI
Ratka, A., Sutanto, W., De Kloet, E.R. , Long-lasting glucocorticoid suppression of opioid-induced antinociception, Neuroendocrinology, vol. 48, no. 4, pp. 439-444. DOI
Elands, J., Beetsma, A., Barberis, C., de Kloet, E.R. , Topography of the oxytocin receptor system in rat brain: an autoradiographical study with a selective radioiodinated oxytocin antagonist, J Chem Neuroanat, vol. 1, no. 6, pp. 293-302.
Reul, J.M., Tonnaer, J.A., De Kloet, E.R. , Neurotrophic ACTH analogue promotes plasticity of type I corticosteroid receptor in brain of senescent male rats, Neurobiol Aging, vol. 9, no. 3, pp. 253-260. DOI
Sutanto, W., van Eekelen, J.A., Reul, J.M., de Kloet, E.R. , Species-specific topography of corticosteroid receptor types in rat and hamster brain, Neuroendocrinology, vol. 47, no. 5, pp. 398-404. DOI
Elands, J., Barberis, C., Jard, S., Lammek, B., Manning, M., Sawyer, W.H., de Kloet, E.R. , 125I-d(CH2)5[Tyr(Me)2, Tyr(NH2)9]AVP: iodination and binding characteristics of a vasopressin receptor ligand, FEBS Lett, vol. 229, no. 2, pp. 251-255. DOI
Elands, J., Resink, A., De Kloet, E.R. , Oxytocin receptors in the rat thymic gland, Eur J Pharmacol, vol. 151, no. 2, pp. 345-346. DOI
Rosenfeld, P., Sutanto, W., Levine, S., De Kloet, E.R. , Ontogeny of type I and type II corticosteroid receptors in the rat hippocampus, Brain Res, vol. 470, no. 1, pp. 113-118.
Rosenfeld, P., Van Eekelen, J.A., Levine, S., De Kloet, E.R. , Ontogeny of the type 2 glucocorticoid receptor in discrete rat brain regions: an immunocytochemical study, Brain Res, vol. 470, no. 1, pp. 119-127.
Ratka, A., Veldhuis, H.D., De Kloet, E.R. , Corticosteroid effects on morphine-induced antinociception as a function of two types of corticosteroid receptors in brain, Neuropharmacology, vol. 27, no. 1, pp. 15-21. DOI
Lebouille, J.L., Burbach, J.P., De Kloet, E.R., Wiegant, V.M., Sweep, C.G., De Wied, D. , Leu-Phe cleaving endopeptidase activity, gamma-endorphin, and beta-endorphin in the rat pituitary gland and brain. Effect of adrenalectomy and corticosterone substitution, Neuroendocrinology, vol. 47, no. 1, pp. 7-12. DOI
Voorhuis, T.A., Kiss, J.Z., de Kloet, E.R., de Wied, D. , Testosterone-sensitive vasotocin-immunoreactive cells and fibers in the canary brain, Brain Res, vol. 442, no. 1, pp. 139-46. DOI
De Kloet, E.R., De Kock, S., Schild, V., Veldhuis, H.D. , Antiglucocorticoid RU 38486 attenuates retention of a behaviour and disinhibits the hypothalamic-pituitary adrenal axis at different brain sites, Neuroendocrinology, vol. 47, no. 2, pp. 109-115. DOI
Kiss, J.Z., Van Eekelen, J.A., Reul, J.M., Westphal, H.M., De Kloet, E.R. , Glucocorticoid receptor in magnocellular neurosecretory cells, Endocrinology, vol. 122, no. 2, pp. 444-449. DOI
Ratka, A., De Kloet, E.R. , Vasopressin and adrenalectomy-induced sensitivity to morphine, Eur J Pharmacol, vol. 153, no. 1, pp. 65-71. DOI
Voorhuis, T.A., de Kloet, E.R., de Wied, D. , The distribution and plasticity of [3H]vasopressin-labelled specific binding sites in the canary brain, Brain Res, vol. 457, no. 1, pp. 148-53. DOI
Seger, M.A., van Eekelen, J.A., Kiss, J.Z., Burbach, J.P., de Kloet, E.R. , Stimulation of pro-opiomelanocortin gene expression by glucocorticoids in the denervated rat intermediate pituitary gland, Neuroendocrinology, vol. 47, no. 4, pp. 350-357. DOI
Molenaar, P.C., Oen, B.S. , Analysis of quantal acetylcholine noise at end-plates of frog muscle during rapid transmitter secretion, J Physiol, vol. 400, no. 1, pp. 335-348.
Sutanto, W., Reul, J.M., van Eekelen, J.A., de Kloet, E.R. , Corticosteroid receptor analyses in rat and hamster brains reveal species specificity in the type I and type II receptors, J Steroid Biochem, vol. 30, no. 1-6, pp. 417-420. DOI
Smit, A.B., Vreugdenhil, E., Ebberink, R.H., Geraerts, W.P., Klootwijk, J., Joosse, J. , Growth-controlling molluscan neurons produce the precursor of an insulin-related peptide, Nature, vol. 331, no. 6156, pp. 535-538. DOI
Lammers, J.H.C.M., Kruk, M.R., Meelis, W., van der Poel, A.M. , Hypothalamic substrates for brain stimulation-induced patterns of locomotion and escape jumps in the rat, Brain Res, vol. 449, no. 1-2, pp. 294-310. DOI
Lammers, J.H.C.M., Kruk, M.R., Meelis, W., van der Poel, A.M. , Hypothalamic substrates for brain stimulation-induced attack, teeth-chattering and social grooming in the rat, Brain Res, vol. 449, no. 1-2, pp. 311-327. DOI
Vreugdenhil, E., Jackson, J.F., Bouwmeester, T., Smit, A.B., van Minnen, J., van Heerikhuizen, H., Klootwijk, J., Joosse, J. , Isolation, characterization, and evolutionary aspects of a cDNA clone encoding multiple neuropeptides involved in the stereotyped egg-laying behavior of the freshwater snail Lymnaea stagnalis, J Neurosci, vol. 8, no. 11, pp. 4184-4191.
De Wied, D., De Kloet, E.R. , Pro-opiomelanocortin and behavioral homeostasis, Hosp Pract (Off Ed), vol. 23, no. 10, pp. 83-91.
van Langevelde, A., van der Molen, H.D., Journee-de Korver, J.G., Paans, A.M., Pauwels, E.K., Vaalburg, W. , Potential radiopharmaceuticals for the detection of ocular melanoma. Part III. A study with 14C and 11C labelled tyrosine and dihydroxyphenylalanine, Eur J Nucl Med, vol. 14, no. 7-8, pp. 382-387. DOI
De Kloet, E.R., Rosenfeld, P., Van Eekelen, J.A., Sutanto, W., Levine, S. , Stress, glucocorticoids and development, Prog Brain Res, vol. 73, pp. 101-20. DOI
Emonds, A.J., Van de Ven, M., Hermans, J., Driessen, O.M. , The elimination of spermidine from plasma in rats, Methods Find Exp Clin Pharmacol, vol. 10, no. 1, pp. 33-37.
Lambalk, C.B., van Rees, G.P., Schoemaker, J., de Koning, J., van Dieten, J.A.M.J. , The influence of pulsatile GnRH administration to the ovariectomized rat on the pituitary response to GnRH and the occurrence of spontaneous LH pulses, Acta Endocrinologica, vol. 117, no. 3, pp. 373-380. DOI
Van der Krogt, J.A., van Valkenburg, C.F.M., Belfroid, R.D. , Tritium isotope effect in reversed-phase high-performance liquid chromatographic analysis of dopamine and dihydroxyphenylacetic acid, J Chromatogr B, vol. 427, no. 1, pp. 9-17. DOI
1987
Kiss, J.Z., Voorhuis, T.A., van Eekelen, J.A., de Kloet, E.R., de Wied, D. , Organization of vasotocin-immunoreactive cells and fibers in the canary brain, J Comp Neurol, vol. 263, no. 3, pp. 347-64. DOI
Sutanto, W., De Kloet, E.R. , Species-specificity of corticosteroid receptors in hamster and rat brains, Endocrinology, vol. 121, no. 4, pp. 1405-1411. DOI
Reul, J.M., van den Bosch, F.R., de Kloet, E.R. , Differential response of type I and type II corticosteroid receptors to changes in plasma steroid level and circadian rhythmicity, Neuroendocrinology, vol. 45, no. 5, pp. 407-412. DOI
Joels, M., Van Veldhuizen, M., Urban, I.J., De Kloet, E.R. , N-acetyl-aspartylglutamate: binding sites and excitatory action in the dorsolateral septum of rats, Brain Res, vol. 403, no. 1, pp. 192-7. DOI
van Eekelen, J.A., Kiss, J.Z., Westphal, H.M., de Kloet, E.R. , Immunocytochemical study on the intracellular localization of the type 2 glucocorticoid receptor in the rat brain, Brain Res, vol. 436, no. 1, pp. 120-8. DOI
de Kloet, E.R., Reul, J.M., van den Bosch, F.R., Tonnaer, J.A., Saito, H. , Ginsenoside RG1 and corticosteroid receptors in rat brain, Endocrinol Jpn, vol. 34, no. 2, pp. 213-220.
De Kloet, E.R., Ratka, A., Reul, J.M., Sutanto, W., Van Eekelen, J.A. , Corticosteroid receptor types in brain: regulation and putative function, Ann N Y Acad Sci, vol. 512, pp. 351-61. DOI
Kruk, M.R., van der Poel, A.M., Lammers, J.H.C.M., Hagg, T., de Hey, A.M.D.M., Oostwegel, S. , Ethopharmacology of hypothalamic aggression in the rat, Ethopharmacology of Agonistic Behaviour in Animals and Humans, Dordrecht, Martinus Nijhoff Publishers, pp. 33-45.
de Greef, W.J., Eilers, G.A., de Koning, J., Karels, B., de Jong, F.H. , Effects of ovarian inhibin on pulsatile release of gonadotrophins and secretion of LHRH in ovariectomized rats: evidence against a central action of inhibin, J Endocrinol, vol. 113, no. 3, pp. 449-455. DOI
Molenaar, P.C., Oen, B.S., Polak, R.L. , Effect of chloride ions on giant miniature end-plate potentials at the frog neuromuscular junction, J Physiol, vol. 383, no. 1, pp. 143-152.
Lammers, J.H.C.M., Meelis, W., Kruk, M.R., van der Poel, A.M. , Hypothalamic substrates for brain stimulation-induced grooming, digging and circling in the rat, Brain Res, vol. 418, no. 1, pp. 1-19. DOI
De Bruijn, E.A., Driessen, O.M., Leeflang, P., Van Strijen, E., van den Bosch, N., Hermans, J. , Interactions of methotrexate and cyclophosphamide with the pharmacokinetics of 5-fluorouracil in an animal model, Cancer Treat Rep, vol. 71, no. 12, pp. 1267-1269.
de Greef, W.J., de Koning, J., Tijssen, A.M. I, Karels, B. , Levels of LH-releasing hormone in hypophysial stalk plasma during an oestrogen-stimulated surge of LH in ovariectomized rats, J Endocrinol, vol. 112, no. 3, pp. 351-359. DOI
Mos, J., Olivier, B., van der Poel, A.M. , Modulatory actions of benzodiazepine receptor ligands on agonistic behaviour, Physiol Behav, vol. 41, no. 3, pp. 265-278. DOI
De Wied, D., De Kloet, E.R. , Pro-opiomelanocortin (POMC) as homeostatic control system, Ann N Y Acad Sci, vol. 512, pp. 328-37. DOI
Emonds, A.J., Driessen, O.M., Leeuwin, R.S., de Vos, D. , pH modulates cisplatin toxicity, Res Commun Chem Pathol Pharmacol, vol. 56, no. 2, pp. 281-284.
Mos, J., Olivier, B., Lammers, J.H.C.M., van der Poel, A.M., Kruk, M.R., Zethof, T. , Postpartum aggression in rats does not influence threshold currents for EBS-induced aggression, Brain Res, vol. 404, no. 1-2, pp. 263-266. DOI
Molenaar, P.C., Oen, B.S., Polak, R.L., van der Laaken, A.L. , Surplus acetylcholine and acetylcholine release in the rat diaphragm, J Physiol, vol. 385, no. 1, pp. 147-167.
1986
McEwen, B.S., De Kloet, E.R., Rostene, W. , Adrenal steroid receptors and actions in the nervous system, Physiol Rev, vol. 66, no. 4, pp. 1121-1188.
de Kloet, E.R., Reul, J.M., de Ronde, F.S., Bloemers, M., Ratka, A. , Function and plasticity of brain corticosteroid receptor systems: action of neuropeptides, J Steroid Biochem, vol. 25, no. 5B, pp. 723-31. DOI
Franken, N.A., Van Langevelde, A., Pauwels, E.K., Journee-de Korver, J.G., Bakker, C.N., Oosterhuis, J.A. , Radio-iodine-labelled 5-iodo-2-thiouracil: a potential radiopharmaceutical for establishing the viability of ocular melanoma after radiation therapy, Nucl Med Commun, vol. 7, no. 11, pp. 797-809.
Koiter, T.R., van der Schaaf-Verdonk, G.C., Broers, S., Pols-Valkhof, N., Schuiling, G.A. , Studies on the modulation of the desensitization of the pituitary gland by luteinizing hormone-releasing hormone in the ovariectomized rat, Experientia, vol. 42, no. 3, pp. 304-307. DOI
Lebouille, J.L., Burbach, J.P., De Kloet, E.R., Rommerts, F.F. , gamma-Endorphin-generating endopeptidase: distribution in body tissues and cellular localization in rat testis, Endocrinology, vol. 118, no. 1, pp. 372-376. DOI
de Kloet, E.R., Voorhuis, D.A., Boschma, Y., Elands, J. , Estradiol modulates density of putative 'oxytocin receptors' in discrete rat brain regions, Neuroendocrinology, vol. 44, no. 4, pp. 415-21. DOI
Jackson, J.F., Vreugdenhil, E., Johnson, K.J., Hall, F.K. , Genes encoding molluscan gonadotropic hormones, Biochem Soc Symp, vol. 52, pp. 83-90.
De Bruijn, E.A., Driessen, O.M., Leeflang, P., van den Bosch, N., Van Strijen, E., Slee, P.H.T.J., Hermans, J. , Pharmacokinetic interactions of cyclophosphamide and 5-fluorouracil with methotrexate in an animal model, Cancer Treat Rep, vol. 70, no. 10, pp. 1159-1165.
Van Langevelde, A., Bakker, C.N., Boer, H., Ilmer, T.A., Journee-de Korver, J.A., Kaspersen, F.M., Noach, E.L., Oosterhuis, J.A., Pauwels, E.K. , Potential radiopharmaceuticals for the detection of ocular melanoma. Part II. Iodoquinoline derivatives and 67Ga-citrate, Eur J Nucl Med, vol. 12, no. 2, pp. 96-104. DOI
De Kloet, E.R., Sijbesma, H., Reul, H.M. , Selective control by corticosterone of serotonin1 receptor capacity in raphe-hippocampal system, Neuroendocrinology, vol. 42, no. 6, pp. 513-521. DOI
Driessen, O.M., Duyff, R.F., Emonds, A.J., Luk, C.M.J., Schuit, J.C. , The influence of anaesthesia on plasma spermidine concentration and renal excretion in rats, Methods Find Exp Clin Pharmacol, vol. 8, no. 7, pp. 431-435.
1985
Veldhuis, H.D., De Korte, C.C., De Kloet, E.R. , Glucocorticoids facilitate the retention of acquired immobility during forced swimming, Eur J Pharmacol, vol. 115, no. 2-3, pp. 211-217. DOI
Franken, N.A., Van Langevelde, A., Journee-De Korver, J.G., Bakker, C.N., Feitsma, R. I, Van Delft, J.L., Oosterhuis, J.A., Pauwels, E.K. , Uptake of 123I-5-iodo-2-thiouracil, a possible radiopharmaceutical for noninvasive detection of ocular melanoma, in melanotic and amelanotic melanomas in hamsters, Nucl Med Commun, vol. 6, no. 10, pp. 657-663.
De Kloet, E.R., Voorhuis, T.A., Elands, J. , Estradiol induces oxytocin binding sites in rat hypothalamic ventromedial nucleus, Eur J Pharmacol, vol. 118, no. 1-2, pp. 185-186. DOI
Sole, M.J., Benedict, C.R., Versteeg, D.H., de Kloet, E.R. , Digitoxin therapy partially restores cardiac catecholamine and brain serotonin metabolism in congestive heart failure, J Mol Cell Cardiol, vol. 17, no. 11, pp. 1055-1063. DOI
de Kloet, E.R., Voorhuis, T.A., Burbach, J.P., de Wied, D. , Autoradiographic localization of binding sites for the arginine-vasopressin (VP) metabolite, VP4-9, in rat brain, Neurosci Lett, vol. 56, no. 1, pp. 7-11. DOI
De Kloet, E.R., Rotteveel, F., Voorhuis, T.A., Terlou, M. , Topography of binding sites for neurohypophyseal hormones in rat brain, Eur J Pharmacol, vol. 110, no. 1, pp. 113-119. DOI
Lebouille, J.L., Burbach, J.P., de Kloet, E.R. , gamma-Endorphin generating endopeptidase in rat brain: subcellular and regional distribution, Biochem Biophys Res Commun, vol. 127, no. 1, pp. 44-8. DOI
Reul, J.M., de Kloet, E.R. , Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation, Endocrinology, vol. 117, no. 6, pp. 2505-2511. DOI
Broxterman, H.J., Smit, J.S., van der Plas, J., Van Langevelde, A., Belfroid, R.D., van Kempen, G.T., Van der Krogt, J.A. , Binding of [3H]flunitrazepam and [3H]spiperone to melanoma cell membrane preparations, Cancer Lett, vol. 28, no. 2, pp. 177-186. DOI
Emonds, A.J., Driessen, O.M. , Does determination of polyamines in body fluids require heating with hydrochloric acid?, Methods Find Exp Clin Pharmacol, vol. 7, no. 10, pp. 535-538.
Oitzl, M.S., Koroleva, V. I, Bures, J. , D-ala2-Metenkephalinamide blocks the synaptically elicited cortical spreading depression in rats, Cellular and Mol Life Sci (Experientia), vol. 41, no. 5, pp. 625-627. DOI
van Dieten, J.A.M.J., van Rees, G.P. , Effect of pretreatment of long-term ovariectomized (OVX) rats with a competitive LRH antagonist on FSH release in vitro, Acta Endocrinologica, vol. 109, no. 4, pp. 481-484. DOI
van Rees, G.P. , LH-RH antagonists--mechanisms of action, Prog Clin Biol Res, vol. 185A, pp. 155-159.
Olivier, B., Mos, J., Van Oorschot, R. , Maternal aggression in rats: effects of chlordiazepoxide and fluprazine, Psychopharmacology, vol. 86, no. 1-2, pp. 68-76. DOI
Buresova, O., Bures, J., Oitzl, M.S., Zahalka, A. , Radial maze in the water tank: an aversively motivated spatial working memory task, Physiol Behav, vol. 34, no. 6, pp. 1003-1005. DOI
Geraerts, W.P.M., Vreugdenhil, E., Ebberink, R.H., Hogenes, T.M. , Synthesis of multiple peptides from a larger precursor in the neuroendocrine caudo-dorsal cells of Lymnaea stagnalis, Neurosci Lett, vol. 56, no. 2, pp. 241-246. DOI
Koroleva, V. I, Oitzl, M.S., Bures, J. , Threshold of synaptically elicited cortical spreading depression: drug-induced changes in rats, Electroencephalogr Clin Neurophysiol, vol. 60, no. 1, pp. 55-64. DOI
Vreugdenhil, E., Geraerts, W.P., Jackson, J.F., Joosse, J. , The molecular basis of the neuro-endocrine control of egg-laying behaviour in Lymnaea, Peptides, vol. 6 Suppl 3, pp. 465-470. DOI
1984
Cottrell, G.A., Nyakas, C., de Kloet, E.R., Bohus, B. , Hippocampal kindling: corticosterone modulation of induced seizures, Brain Res, vol. 309, no. 2, pp. 377-81. DOI
Rigter, H., Veldhuis, H.D., de Kloet, E.R. , Spatial learning and the hippocampal corticosterone receptor system of old rats: effect of the ACTH4-9 analogue ORG 2766, Brain Res, vol. 309, no. 2, pp. 389-392 . DOI
van Heuven-Nolsen, D., de Kloet, E.R., Versteeg, D.H. , Pro-Leu-GlyNH2 affects dopamine and noradrenaline utilization in rat limbic-forebrain nuclei, Brain Res, vol. 322, no. 2, pp. 213-218. DOI
van den Buuse, M., de Kloet, E.R., Versteeg, D.H., de Jong, W. , Regional brain catecholamine levels and the development of hypertension in the spontaneously hypertensive rat: the effect of 6-hydroxydopamine, Brain Res, vol. 301, no. 2, pp. 221-229. DOI
Laczi, F., Gaffori, O., Fekete, M., de Kloet, E.R., de Wied, D. , Levels of arginine-vasopressin in cerebrospinal fluid during passive avoidance behavior in rats, Life Sci, vol. 34, no. 24, pp. 2385-2391. DOI
Cottrell, G.A., Veldhuis, H.D., Rostene, W.H., de Kloet, E.R. , Behavioral actions of vasoactive intestinal peptide (VIP), Neuropeptides, vol. 4, no. 4, pp. 331-341. DOI
Borrell, J., de Kloet, E.R., Bohus, B. , Corticosterone decreases the efficacy of adrenaline to affect passive avoidance retention of adrenalectomized rats, Life Sci, vol. 34, no. 1, pp. 99-104. DOI
Versteeg, D.H., Van Zoest, I, De Kloet, E.R. , Acute changes in dopamine metabolism in the medio-basal hypothalamus following adrenalectomy, Cellular and Mol Life Sci (Experientia), vol. 40, no. 1, pp. 112-114. DOI
de Kloet, E.R. , Adrenal steroids as modulators of nerve cell function, J Steroid Biochem, vol. 20, no. 1, pp. 175-181. DOI
de Kloet, E.R., Voorhuis, T.A., Leunissen, J.L., Koch, B. , Intracellular CBG-like molecules in the rat pituitary, J Steroid Biochem, vol. 20, no. 1, pp. 367-371. DOI
Biegon, A., Terlou, M., Voorhuis, T.D., de Kloet, E.R. , Arginine-vasopressin binding sites in rat brain: a quantitative autoradiographic study, Neurosci Lett, vol. 44, no. 3, pp. 229-234. DOI
van Heuven-Nolsen, D., De Kloet, E.R., De Wied, D., Versteeg, D.H. , Microinjection of vasopressin and two related peptides into the amygdala: enhancing effect on local dopamine neurotransmission, Brain Res, vol. 293, no. 1, pp. 191-195. DOI
Burbach, J.P., De Hoop, M.J., Schmale, H., Richter, D., De Kloet, E.R., Ten Haaf, J.A., De Wied, D. , Differential responses to osmotic stress of vasopressin-neurophysin mRNA in hypothalamic nuclei, Neuroendocrinology, vol. 39, no. 6, pp. 582-584. DOI
van Heuven-Nolsen, D., De Kloet, E.R., Versteeg, D.H. , Oxytocin affects utilization of noradrenaline in distinct limbic-forebrain regions of the rat brain, Neuropharmacology, vol. 23, no. 12A, pp. 1373-1377. DOI
de Kloet, E.R., Veldhuis, H.D., Wagenaars, J.L., Bergink, E.W. , Relative binding affinity of steroids for the corticosterone receptor system in rat hippocampus, J Steroid Biochem, vol. 21, no. 2, pp. 173-178. DOI
Miledi, R., Molenaar, P.C., Polak, R.L. , Acetylcholinesterase activity in intact and homogenized skeletal muscle of the frog, J Physiol, vol. 349, no. 1, pp. 663-686.
van der Poel, A.M., Mos, J., Kruk, M.R., Olivier, B. , A motivational analysis of ambivalent actions in the agonistic behaviour of rats in tests used to study effects of drugs on aggression, Prog Clin Biol Res, vol. 167, pp. 115-135.
van Valkenburg, C.F.M., Van der Krogt, J.A., Moleman, P., van Berkum, H., Tjaden, U., de Jong, J. , A procedure to measure the specific activities of dopamine and its metabolites in rat striatum, based on HPLC, electrochemical detection and liquid scintillation counting, J Neurosci Methods, vol. 11, no. 1, pp. 29-38. DOI
Kruk, M.R., Van der Laan, C.E., Meelis, W., Phillips, R.E., Mos, J., van der Poel, A.M. , Brain-stimulation induced agonistic behaviour: a novel paradigm in ethopharmacological aggression research, Prog Clin Biol Res, vol. 167, pp. 157-177.
Mos, J., Witte, M.M., Olivier, B., van der Poel, A.M., Kruk, M.R. , Behavioural voltammetry: its application in aggression research, Prog Clin Biol Res, vol. 167, pp. 179-189.
Kruk, M.R., Van der Laan, C.E., Mos, J., van der Poel, A.M., Meelis, W., Olivier, B. , Comparison of aggressive behaviour induced by electrical stimulation in the hypothalamus of male and female rats, Prog Brain Res, vol. 61, pp. 303-314. DOI
Mos, J., Olivier, B., Van Oorschot, R., Dijkstra, H. , Different test situations for measuring offensive aggression in male rats do not result in the same wound pattern, Physiol Behav, vol. 32, no. 3, pp. 453-456. DOI
Moleman, P., van Valkenburg, C.F.M., Van der Krogt, J.A. , Effects of morphine on dopamine metabolism in rat striatum and limbic structures in relation to the activity of dopaminergic neurones, Naunyn Schmiedebergs Arch Pharmacol, vol. 327, no. 3, pp. 208-213. DOI
Olivier, B., Mos, J., van der Poel, A.M., Krijzer, F.N., Kruk, M.R. , Effects of a new psychoactive drug (DU 27716) on different models of rat agonistic behaviour and EEG, Prog Clin Biol Res, vol. 169, pp. 261-279.
de Kloet, E.R. , Function of steroid receptor systems in the central nervous system, Clin Neuropharmacol, vol. 7, no. 4, pp. 272-80.
Straathof, D.J., Driessen, O.M., Meijer, J.W.A., Van Rees, H., Vermeij, P., Vermeij, T.A.C. , Influence of Intralipid infusion on the elimination of phenytoin, Arch Int Pharmacodyn Ther, vol. 267, no. 2, pp. 180-186.
Haffmans, J., De Kloet, E.R., Dzoljic, M.R. , Metabolic rate in different rat brain areas during seizures induced by a specific delta opiate receptor agonist, Brain Res, vol. 302, no. 1, pp. 111-115. DOI
Lang, B., Molenaar, P.C., Newsom-Davis, J., Vincent, A. , Passive transfer of Lambert-Eaton myasthenic syndrome in mice: decreased rates of resting and evoked release of acetylcholine from skeletal muscle, J Neurochem, vol. 42, no. 3, pp. 658-662. DOI
Driessen, O.M., Emonds, A.J., Luk, C.M.J., Van Rees, H. , The fate of infused spermidine in the plasma of rats, Methods Find Exp Clin Pharmacol, vol. 6, no. 9, pp. 491-496.
1983
De Kloet, E.R., Cousin, M.A., Veldhuis, H.D., Voorhuis, T.D., Lando, D. , Glucocorticoids modulate the response of ornithine decarboxylase to unilateral removal of the dorsal hippocampus, Brain Res, vol. 275, no. 1, pp. 91-8. DOI
Mens, W.B., Laczi, F., Tonnaer, J.A., de Kloet, E.R., van Wimersma Greidanus, T.B. , Vasopressin and oxytocin content in cerebrospinal fluid and in various brain areas after administration of histamine and pentylenetetrazol, Pharmacol Biochem Behav, vol. 19, no. 4, pp. 587-591. DOI
Borrell, J., De Kloet, E.R., Versteeg, D.H., Bohus, B. , Inhibitory avoidance deficit following short-term adrenalectomy in the rat: the role of adrenal catecholamines, Behav Neural Biol, vol. 39, no. 2, pp. 241-258. DOI
Broxterman, H.J., van Langevelde, A., Bakker, C.N., Boer, H., Journee-de Korver, J.G., Kaspersen, F.M., Kakebeeke-Kemme, H.M., Pauwels, E.K. , Incorporation of [125I]-5-iodo-2-thiouracil in cultured hamster, rabbit, and human melanoma cells, Cancer Res, vol. 43, no. 3, pp. 1316-1320.
Laczi, F., Gaffori, O., de Kloet, E.R., de Wied, D. , Differential responses in immunoreactive arginine-vasopressin content of microdissected brain regions during passive avoidance behavior, Brain Res, vol. 260, no. 2, pp. 342-346. DOI
Laczi, F., Gaffori, O., De Kloet, E.R., De Wied, D. , Arginine-vasopressin content of hippocampus and amygdala during passive avoidance behavior in rats, Brain Res, vol. 280, no. 2, pp. 309-15. DOI
Nyakas, C., De Kloet, E.R., Veldhuis, H.D., Bohus, B. , Hippocampal corticosterone receptors and novelty-induced behavioral activity: effect of kainic acid lesion in the hippocampus, Brain Res, vol. 288, no. 1-2, pp. 219-28. DOI
De Kloet, E.R., Versteeg, D.H., Kovacs, G.L. , Aldosterone blocks the response to corticosterone in the raphe-hippocampal serotonin system, Brain Res, vol. 264, no. 2, pp. 323-7. DOI
Sole, M.J., Versteeg, D.H., de Kloet, E.R., Hussain, N., Lixfeld, W. , The identification of specific serotonergic nuclei inhibited by cardiac vagal afferents during acute myocardial ischemia in the rat, Brain Res, vol. 265, no. 1, pp. 55-61. DOI
De Kloet, E.R., Drago, F., Mezey, E., Bohus, B., De Wied, D. , Pituitary stalk section transiently impairs the acquisition of shuttle box avoidance behavior, Physiol Behav, vol. 30, no. 4, pp. 499-502. DOI
de Jong, J., Tjaden, U.R., Hof, W., van Valkenburg, C.F.M. , Analysis of serotonin and derivatives by reversed-phase ion-pair partition chromatography with fluorometric and electrochemical detection, J Chromatogr, vol. 282, pp. 443-456. DOI
van der Poel, A.M., van der Hoef, H., Meelis, W., Vletter, G., Mos, J., Kruk, M.R. , A locked, non-rotating, completely embedded, moveable electrode for chronic brain stimulation studies in freely moving, fighting rats, Physiol Behav, vol. 31, no. 2, pp. 259-263. DOI
Emonds, A.J., Driessen, O.M. , Determination of polyamines in plasma by capillary gas chromatography and some applications, Methods Find Exp Clin Pharmacol, vol. 5, no. 6, pp. 391-396.
Kruk, M.R., van der Poel, A.M., Meelis, W., Hermans, J., Mostert, P.G., Mos, J., Lohman, A.H. , Discriminant analysis of the localization of aggression-inducing electrode placements in the hypothalamus of male rats, Brain Res, vol. 260, no. 1, pp. 61-79. DOI
Miledi, R., Molenaar, P.C., Polak, R.L. , Electrophysiological and chemical determination of acetylcholine release at the frog neuromuscular junction, J Physiol, vol. 334, no. 1, pp. 245-254.
Mos, J., Lammers, J.H.C.M., van der Poel, A.M., Bermond, B., Meelis, W., Kruk, M.R. , Effects of Midbrain Central Gray Lesions on Spontaneous and Electrically Induced Aggression in the Rat, Aggressive Behavior, vol. 9, no. 2, pp. 133-155. DOI
Van Rees, H., Telkers-Duijts, G.A., Noach, E.L. , Folic acid and the protective action of diphenylhydantoin against maximal electroshock in rats after single doses, Arch Int Pharmacodyn Ther, vol. 261, no. 1, pp. 16-22.
Natarajan, A.T., De Bruijn, E.A., Leeflang, P., Slee, P.H.T.J., Mohn, G.R., Driessen, O.M. , Induction of chromosomal alterations as an assay for cytostatic drug activity in plasma, Mutat Res, vol. 121, no. 1, pp. 39-45. DOI
Molenaar, P.C., Polak, R.L. , Potassium propionate causes preferential loss of 'bound' acetylcholine in frog muscle, Neurosci Lett, vol. 43, no. 2-3, pp. 209-213. DOI
van Langevelde, A., Bakker, C.N., Broxterman, H.J., Journee-de Korver, J.G., Kaspersen, F.M., Oosterhuis, J.A., Pauwels, E.K. , Potential radiopharmaceuticals for the detection of ocular melanoma. Part I. 5-iodo-2-thiouracil derivatives, Eur J Nucl Med, vol. 8, no. 2, pp. 45-51. DOI
Van der Krogt, J.A., Koot-Gronsveld, E., Van den Berg, C.J. , Subcellular fractionation of striatum: sedimentation properties of dopaminergic synaptosomes, Life Sci, vol. 33, no. 7, pp. 605-613. DOI
1982
De Kloet, E.R., Kovacs, G.L., Szabo, G., Telegdy, G., Bohus, B., Versteeg, D.H. , Decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution, Brain Res, vol. 239, no. 2, pp. 659-63. DOI
Sole, M.J., Hussain, M.N., Versteeg, D.H., de Kloet, E.R., Adams, D., Lixfeld, W. , The identification of specific brain nuclei in which catecholamine turnover is increased by left ventricular receptors during acute myocardial infarction in the rat, Brain Res, vol. 235, no. 2, pp. 315-325. DOI
Veldhuis, H.D., De Kloet, E.R., Van Zoest, I, Bohus, B. , Adrenalectomy reduces exploratory activity in the rat: a specific role of corticosterone, Horm Behav, vol. 16, no. 2, pp. 191-198. DOI
Veldhuis, H.D., Van Koppen, C., Van Ittersum, M., De Kloet, E.R. , Specificity of the adrenal steroid receptor system in rat hippocampus, Endocrinology, vol. 110, no. 6, pp. 2044-2051. DOI
Versteeg, D.H., Kovacs, G.L., Bohus, B., de Kloet, E.R., de Wied, D. , Effect of des-Tyr1-gamma-endorphin and des-Tyr1-alpha-endorphin on alpha-MPT-induced catecholamine disappearance in rat brain nuclei: a dose--response study, Brain Res, vol. 231, no. 2, pp. 343-351. DOI
Versteeg, D.H., De Kloet, E.R., Szabo, G., Kovacs, G.L. , The effects of des-enkephalin-gamma-endorphin and des-Tyr1-a-endorphin on regional serotonin metabolism in rat brain, Brain Res, vol. 245, no. 2, pp. 384-388. DOI
Bermond, B., Mos, J., Meelis, W., van der Poel, A.M., Kruk, M.R. , Aggression induced by stimulation of the hypothalamus: effects of androgens, Pharmacol Biochem Behav, vol. 16, no. 1, pp. 41-45. DOI
van der Poel, A.M., Olivier, B., Mos, J., Kruk, M.R., Meelis, W., van Aken, J.H. , Anti-aggressive effect of a new phenylpiperazine compound (DU27716) on hypothalamically induced behavioural activities, Pharmacol Biochem Behav, vol. 17, no. 1, pp. 147-153. DOI
van Haeringen, N.J., Oosterhuis, J.A., van Delft, J.L., Glasius, E., Noach, E.L. , A comparison of the effects of non-steroidal compounds on the disruption of the blood-aqueous barrier, Exp Eye Res, vol. 35, no. 3, pp. 271-277. DOI
van Valkenburg, C.F.M., Tjaden, U., Van der Krogt, J.A., Van der Leden, B. , Determination of dopamine and its acidic metabolites in brain tissue by HPLC with electrochemical detection in a single run after minimal sample pretreatment, J Neurochem, vol. 39, no. 4, pp. 990-997. DOI
Miledi, R., Molenaar, P.C., Polak, R.L. , Free and bound acetylcholine in frog muscle, J Physiol, vol. 333, no. 1, pp. 189-199.
Miledi, R., Molenaar, P.C., Polak, R.L., Tas, J.W., van der Laaken, T. , Neural and non-neural acetylcholine in the rat diaphragm, Proc R Soc Lond B Biol Sci, vol. 214, no. 1195, pp. 153-168. DOI
Van der Krogt, J.A., van Valkenburg, C.F.M., Belfroid, R.D. , Rat brain monoamine oxidase activity is not affected by repeated administration of haloperidol, J Pharm Pharmacol, vol. 34, no. 8, pp. 529-531. DOI
Angelucci, L., Patacchioli, F.R., Bohus, B., De Kloet, E.R. , Serotoninergic innervation and glucocorticoid binding in the hippocampus: relevance to depression, Adv Biochem Psychopharmacol, vol. 31: Also in "Typical and Atypical antidepressants. Raven Press, New York", pp. 365-370.
Veldhuis, H.D., De Kloet, E.R. , Significance of ACTH4-10 in the control of hippocampal corticosterone receptor capacity of hypophysectomized rats, Neuroendocrinology, vol. 34, no. 5, pp. 374-380. DOI
1981
Kovacs, G.L., Versteeg, D.H., de Kloet, E.R., Bohus, B. , Passive avoidance performance correlates with catecholamine turnover in discrete limbic brain regions, Life Sci, vol. 28, no. 10, pp. 1109-1116. DOI
Nyakas, C., de Kloet, E.R., Veldhuis, H.D., Bohus, B. , Corticosterone binding capacity increases in contralateral hippocampus after partial unilateral hippocampectomy, Neurosci Lett, vol. 21, no. 3, pp. 339-343. DOI
van Dijk, A.M., van Wimersma Greidanus, T.B., Burbach, J.P., de Kloet, E.R., de Wied, D. , Brain adrenocorticotrophin after adrenalectomy and sham-operation of rats, J Endocrinol, vol. 88, no. 2, pp. 243-253. DOI
Burbach, J.P., De Kloet, E.R., Schotman, P., De Wied, D. , Proteolytic conversion of beta-endorphin by brain synaptic membranes. Characterization of generated beta-endorphin fragments and proposed metabolic pathway, J Biol Chem, vol. 256, no. 23, pp. 12463-12469.
Mos, J. , The midbrain central gray and aggression in male rats, Medical Faculty, Pharmacology, vol. PhD, Leiden, Leiden, pp. 104 p..
Broxterman, H.J., Noach, E.L., van Valkenburg, C.F.M., Wijling, A. , Cross-tolerance of dopamine metabolism to baclofen, gamma-butyrolactone and HA-966 in the striatum and olfactory tubercle of the rat, Life Sci, vol. 28, no. 9, pp. 973-981. DOI
De Groot, C.A., Tijssen, A.M. I , Dissociation of antipolyuric action and increase in plasma renin activity caused by chlorothiazide in Brattleboro rats, Arch Int Pharmacodyn Ther, vol. 253, no. 1, pp. 137-147.
van Dieten, J.A.M.J., van Valkenburg, C.F.M., de Koning, J., van Rees, G.P. , Dopaminergic and adrenergic effects on plasma LH levels in rats with hypothalamic islands, Acta Endocrinologica, vol. 97, no. 3, pp. 289-296. DOI
Mos, J., Broxterman, H.J., Van Bennekom, W.P. , In vivo voltammetric investigations into the action of HA-966 on central dopaminergic neurons, Brain Res, vol. 207, no. 2, pp. 465-470. DOI
Robbins, N., Molenaar, P.C. , Investigation of possible cholinergic mechanisms in fertilization of Xenopus eggs, Proc R Soc Lond B Biol Sci, vol. 213, no. 1190, pp. 59-72. DOI
de Kloet, E.R., Palkovits, M., Mezey, E. , Opiocortin peptides: localization, source and avenues of transport, Pharmacol Ther, vol. 12, no. 2, pp. 321-351. DOI
Sprick, U., Oitzl, M.S., Ornstein, K., Huston, J.P. , Spreading depression induced by microinjection of enkephalins into the hippocampus and neocortex, Brain Res, vol. 210, no. 1-2, pp. 243-252. DOI
1980
Ponec, M., De Kloet, E.R., Kempenaar, J.A. , Corticoids and human skin fibroblasts: intracellular specific binding in relation to growth inhibition, J Invest Dermatol, vol. 75, no. 4, pp. 293-296. DOI
Burbach, J.P., Loeber, J.G., Verhoef, J., Wiegant, V.M., de Kloet, E.R., de Wied, D. , Selective conversion of beta-endorphin into peptides related to gamma- and alpha-endorphin, Nature, vol. 283, no. 5742, pp. 96-97. DOI
Burbach, J.P., Loeber, J.G., Verhoef, J., de Kloet, E.R. , beta-Endorphin biotransformation in brain: formation of gamma-endorphin by a synaptosomal plasma membrane associated endopeptidase distinct from cathepsin D, Biochem Biophys Res Commun, vol. 92, no. 2, pp. 725-32. DOI
Wijnen, H.J., Spierenburg, H.A., de Kloet, E.R., de Jong, W., Versteeg, D.H. , Decrease in noradrenergic activity in hypothalamic nuclei during the development of spontaneous hypertension, Brain Res, vol. 184, no. 1, pp. 153-162. DOI
de Kloet, E.R., Veldhuis, H.D. , The hippocampal corticosterone receptor system of the homozygous diabetes insipidus (Brattleboro) rat, Neurosci Lett, vol. 16, no. 2, pp. 187-192. DOI
Burbach, J.P., Schotman, P., Verhoef, J., de Kloet, E.R., de Wied, D. , Conversion of des-tyrosine-gamma-endorphin by brain synaptic membrane associated peptidases: identification of generated peptide fragments, Biochem Biophys Res Commun, vol. 97, no. 3, pp. 995-1004. DOI
Burbach, J.P., Schotman, P., de Kloet, E.R. , Oxytocin biotransformation in the rat limbic brain: chemical characterization of two oxytocin fragments and proposed pathway for oxytocin conversion, Biochem Biophys Res Commun, vol. 97, no. 3, pp. 1005-13. DOI
Broxterman, H.J., Noach, E.L., de Vos, D. , Assay of HA-966 in rat plasma by capillary gas-liquid chromatography with nitrogen-selective detection, J Chromatogr B, vol. 183, no. 2, pp. 185-191. DOI
Molenaar, P.C., Polak, R.L. , Acetylcholine synthesizing enzymes in frog skeletal muscle, J Neurochem, vol. 35, no. 5, pp. 1021-1025. DOI
Broxterman, H.J., Mos, J. , Dopamine hypoactivity measured by in vivo voltammetry, Eur J Pharmacol, vol. 68, no. 3, pp. 389-391. DOI
Broxterman, H.J., van Valkenburg, C.F.M., Noach, E.L. , HA-966 effects on striatal dopamine metabolism: implications for dopamine compartmentalization, J Pharm Pharmacol, vol. 32, no. 1, pp. 67-69. DOI
Schuiling, G.A., Zurcher, A.F., Pols-Valkhof, N., Koiter, T.R. , On the development of pituitary responsiveness to LRH and the characteristics of pre-ovulatory LH-surges in the rat. Effect of oestradiol benzoate, Acta Endocrinologica, vol. 93, no. 2, pp. 162-167. DOI
De Kloet, E.R., Veldhuis, D., Bohus, B. , Significance of neuropeptides in the control of corticosterone receptor activity in rat brain, Adv Biochem Psychopharmacol, vol. 21, pp. 373-382.
Schuiling, G.A., Pols-Valkhof, N., Zurcher, A.F. , Some observations concerning the role of progesterone in the control of ovulation, Acta Endocrinologica, vol. 94, no. 2, pp. 246-250. DOI
Miledi, R., Molenaar, P.C., Polak, R.L. , The effect of lanthanum ions on acetylcholine in frog muscle, J Physiol, vol. 309, no. 1, pp. 199-214.
1979
Kovacs, G.L., Bohus, B., Versteeg, D.H., de Kloet, E.R., de Wied, D. , Effect of oxytocin and vasopressin on memory consolidation: sites of action and catecholaminergic correlates after local microinjection into limbic-midbrain structures, Brain Res, vol. 175, no. 2, pp. 303-314. DOI
Van der Heyden, J.A., de Kloet, E.R., Korf, J., Versteeg, D.H. , GABA content of discrete brain nuclei and spinal cord of the rat, J Neurochem, vol. 33, no. 4, pp. 857-861. DOI
Dorsa, D.M., de Kloet, E.R., Mezey, E., de Wied, D. , Pituitary-brain transport of neurotensin: functional significance of retrograde transport, Endocrinology, vol. 104, no. 6, pp. 1663-1666. DOI
Versteeg, D.H., De Kloet, E.R., van Wimersma Greidanus, T.B., De Wied, D. , Vasopressin modulates the activity of catecholamine containing neurons in specific brain regions, Neurosci Lett, vol. 11, no. 1, pp. 69-73. DOI
Burbach, J.P., Loeber, J.G., Verhoef, J., de Kloet, E.R., de Wied, D. , Biotransformation of endorphins by a synaptosomal plasma membrane preparation of rat brain and by human serum, Biochem Biophys Res Commun, vol. 86, no. 4, pp. 1296-303. DOI
Molenaar, P.C., Polak, R.L., Miledi, R., Alema, S., Vincent, A., Newsom-Davis, J. , Acetylcholine in intercostal muscle from myasthenia gravis patients and in rat diaphragm after blockade of acetylcholine receptors, Prog Brain Res, vol. 49, pp. 449-458. DOI
Schuiling, G.A., Pols-Valkhof, N., Koiter, T.R. , A possible role of corpora lutea with regard to oestrogen-induced changes in pituitary responsiveness to LH-RH, Acta Endocrinologica, vol. 92, no. 1, pp. 46-61. DOI
Gnodde, H.P., van Dieten, J.A.M.J., van Rees, G.P., Rothchild, I , Conversion of progesterone to testosterone in the rat Leydig cell, Proc Soc Exp Biol Med, vol. 160, no. 1, pp. 130-133.
Broxterman, H.J., Noach, E.L., van Valkenburg, C.F.M. , Differential effects of acute and subacute HA-966 treatment on storage and release of striatal dopamine, Eur J Pharmacol, vol. 60, no. 2-3, pp. 153-161. DOI
Gnodde, H.P., van Dieten, J.A.M.J., Van Look, P.F. , Effect of androstenedione on the oestrous cycle of the rat, J Reprod Fertil, vol. 56, no. 2, pp. 675-678. DOI
van Wimersma Greidanus, T.B., Croiset, G., Schuiling, G.A. , Fornix transection: discrimination between neuropeptide effects on attention and memory, Brain Res Bull, vol. 4, no. 5, pp. 625-629. DOI
Nyakas, C., de Kloet, E.R., Bohus, B. , Hippocampal function and putative corticosterone receptors. Effect of septal lesions, Neuroendocrinology, vol. 29, no. 5, pp. 301-312. DOI
van Valkenburg, C.F.M., Noach, E.L., Wijling, A. , Involvement of the nerve impulse flow in the release of extragranular dopamine, Eur J Pharmacol, vol. 57, no. 2-3, pp. 191-199. DOI
Koiter, T.R., Pols-Valkhof, N., Zurcher, A.F., Schuiling, G.A. , LH-secretory responses caused by continuous infusion of LH-RH in pseudopregnant rats, Acta Endocrinologica, vol. 92, no. 1, pp. 28-45. DOI
Mos, J., van Valkenburg, C.F.M. , Specific effect on social stess and aggression on regional dopamine metabolism in rat brain, Neurosci Lett, vol. 15, no. 2-3, pp. 325-327. DOI
De Groot, C.A., Tijssen, A.M. I , The effects of long-term oral treatment with chlorothiazide or furosemide on hereditary diabetes insipidus in rats, Arch Int Pharmacodyn Ther, vol. 237, no. 1, pp. 75-87.
Kruk, M.R., van der Poel, A.M., de Vos-Frerichs, T.P. , The induction of aggressive behaviour by electrical stimulation in the hypothalamus of male rats, Behaviour, vol. 70, no. 3-4, pp. 292-322. DOI
1978
Versteeg, D.H., Tanaka, M., de Kloet, E.R. , Catecholamine concentration and turnover in discrete regions of the brain of the homozygous Brattleboro rat deficient in vasopressin, Endocrinology, vol. 103, no. 5, pp. 1654-1661. DOI
Versteeg, D.H., Tanaka, M., De Kloet, E.R., Van Ree, J.M., De Wied, D. , Prolyl-leucyl-glycinamide (PLG); regional effects on alpha-MPT-induced catecholamine disappearance in rat brain, Brain Res, vol. 143, no. 3, pp. 561-566. DOI
Mezey, E., Palkovits, M., de Kloet, E.R., Verhoef, J., de Wied, D. , Evidence for pituitary-brain transport of a behaviorally potent ACTH analog, Life Sci, vol. 22, no. 10, pp. 831-838. DOI
de Kloet, E.R., Burbach, P. , Selective purification of a single population of glucocorticoid receptors from rat brain, J Neurochem, vol. 30, no. 6, pp. 1505-1507. DOI
Wijnen, H.J., De Kloet, E.R., Versteeg, D.H., De Jong, W. , Differences in regional brain catecholamine metabolism after a decrease in blood pressure, Life Sci, vol. 23, no. 26, pp. 2587-2591. DOI
Kruk, M.R., Kuiper, P., Meelis, W. , An air pressure operated commutator system for electrical brain stimulation in a fighting rat, Physiol Behav, vol. 21, no. 1, pp. 125-127. DOI
Miledi, R., Molenaar, P.C., Polak, R.L. , Alpha-Bungarotoxin enhances transmitter "released" at the neuromuscular junction, Nature, vol. 272, no. 5654, pp. 641-643. DOI
van Valkenburg, C.F.M., Noach, E.L. , Electrical stimulation of the nigrostriatal pathway after HA-966 block of triatal dopamine release, Eur J Pharmacol, vol. 48, no. 2, pp. 171-177. DOI
Kok-van Alphen, C.C., Noach, E.L. , Hormonal influences on ocular refraction in the rat, Nature, vol. 271, no. 5640, pp. 62-64. DOI
Moleman, P., Bruinvels, J., van Valkenburg, C.F.M. , Haloperidol inhibits the disappearance of acidic dopamine metabolites from rat striatum, J Pharm Pharmacol, vol. 30, no. 1, pp. 583-585. DOI
Moleman, P., Bruinvels, J., van Valkenburg, C.F.M. , On the relation between haloperidol-induced alterations in DA release and DA metabolism in rat striatum, Life Sci, vol. 23, no. 6, pp. 611-615. DOI
Herfst, M.J., Van Rees, H. , Suction blister fluid as a model for interstitial fluid in rats, Arch Dermatol Res, vol. 263, no. 3, pp. 325-334. DOI
Emonds, A.J., Driessen, O.M. , Treatment of theophylline intoxication: a model study utilizing peritoneal dialysis, Clin Toxicol, vol. 13, no. 4, pp. 505-511. DOI
1977
van der Gugten, J., de Kloet, E.R., Versteeg, H.G., Slangen, J.L. , Regional hypothalamic catecholamine metabolism and food intake regulation in the rat, Brain Res, vol. 135, no. 2, pp. 325-336. DOI
de Kloet, E.R., Burbach, P., Mulder, G.H. , Localization and role of transcortin-like molecules in the anterior pituitary, Mol Cell Endocrinol, vol. 7, no. 3, pp. 261-273. DOI
Tanaka, M., de Kloet, E.R., de Wied, D., Versteeg, D.H. , Arginine8-vasopressin affects catecholamine metabolism in specific brain nuclei, Life Sci, vol. 20, no. 11, pp. 1799-1808. DOI
Miledi, R., Molenaar, P.C., Polak, R.L. , An analysis of acetylcholine in frog muscle by mass fragmentography, Proc R Soc Lond B Biol Sci, vol. 197, no. 1128, pp. 285-297. DOI
Polak, R.L., Molenaar, P.C., van Gelder, M. , Acetylcholine metabolism and choline uptake in cortical slices, J Neurochem, vol. 29, no. 3, pp. 477-485. DOI
1976
De Kloet, E.R., McEwen, B.S. , A putative glucocorticoid receptor and a transcortin-like macromolecule in pituitary cytosol, Biochim Biophys Acta, vol. 421, no. 1, pp. 115-123. DOI
De Kloet, E.R., McEwen, B.S. , Differences between cytosol receptor complexes with corticosterone and dexamethasone in hippocampal tissue from rat brain, Biochim Biophys Acta, vol. 421, no. 1, pp. 124-132. DOI
Driessen, O.M., Thesingh, C.W., van den Bosch, N. , Autoradiographic model experiments with 67Ga and 99mTc, Histochemistry and Cell Biology, vol. 50, no. 1, pp. 77-80. DOI
Van Zwieten-Boot, B.J., Petri-Bot, A. , Absence of a 'cholinergic link' in the apomorphine-induced feedback inhibition of dopamine synthesis in rat striatum, Eur J Pharmacol, vol. 39, no. 2, pp. 245-250. DOI
Kok-van Alphen, C.C., Noach, E.L., Laman, D. , Endocrine influences on the refraction of the eyes of young rats, Ophthalmologica, vol. 173, no. 3-4, pp. 328-332. DOI
Schuiling, G.A., de Koning, J., Zurcher, A.F., Gnodde, H.P., van Rees, G.P. , Induction of LH surges by continuous infusion of LH-RH1, Neuroendocrinology, vol. 20, no. 2, pp. 151-156. DOI
Schuiling, G.A., Gnodde, H.P. , Site of origin of the pulsatile secretion of luteinizing hormone in long-term ovariectomized rats, J Endocrinol, vol. 70, no. 1, pp. 97-104. DOI
1975
McEwen, B.S., Luine, V.N., Plapinger, L., de Kloet, E.R. , Putative estrogen and glucocorticoid receptors in the limbic brain, J Steroid Biochem, vol. 6, no. 6, pp. 971-977. DOI
Meinardi, H., Van Der Kleijn, E., Meijer, J.W., Van Rees, H. , Absorption and distribution of antiepileptic drugs, Epilepsia, vol. 16, no. 2, pp. 353-365. DOI
De Kloet, E.R., Wallach, G., McEwen, B.S. , Differences in corticosterone and dexamethasone binding to rat brain and pituitary, Endocrinology, vol. 96, no. 3, pp. 598-609. DOI
Kok-van Alphen, C.C., Noach, E.L. , Endocrine influences on the refraction of the eyes of young rats, Exp Eye Res, vol. 20, no. 2, pp. 179-179. DOI
Van Zwieten-Boot, B.J., Noach, E.L. , The effect of blocking dopamine release on synthesis rate of dopamine in the striatum of the rat, Eur J Pharmacol, vol. 33, no. 2, pp. 247-254. DOI
1974
de Kloet, E.R., van der Vies, J., de Wied, D. , The site of the suppressive action of dexamethasone on pituitary-adrenal activity, Endocrinology, vol. 94, no. 1, pp. 61-73. DOI
Schuiling, G.A., van Rees, G.P. , Evidence of an extra-hypothalamic inhibitory influence on the secretion of gonadotropins in the female rat, Neuroendocrinology, vol. 15, no. 2, pp. 73-78. DOI
Schuiling, G.A., van Dieten, J.A.M.J., van Rees, G.P. , Induction and inhibition of ovulation in the rat by intracerebral progesterone implants, Neuroendocrinology, vol. 15, no. 1, pp. 38-50. DOI
Polak, R.L., Molenaar, P.C. , Pitfalls in determination of acetylcholine from brain by pyrolysis-gas chromatography/mass spectrometry, J Neurochem, vol. 23, no. 6, pp. 1295-1297. DOI
Thesingh, C.W., Driessen, O.M., van den Bosch, N. , The localization of 125-iodide and iodinated (125I) albumin in autoradiographic model experiments, Histochemistry and Cell Biology, vol. 39, no. 4, pp. 345-349. DOI
van der Poel, A.M. , The influence of 3-quinuclidinylbenzilate on the behaviour of rats in a circular runway, Psychopharmacologia, vol. 36, no. 2, pp. 151-162. DOI
van Dieten, J.A.M.J., Steijsiger, J., Dullaart, J., van Rees, G.P. , The effect of estradiol benzoate on the pituitary responsiveness to LH-RH in male and female rats, Neuroendocrinology, vol. 15, no. 3-4, pp. 182-188. DOI
Van Rees, H., De Wolff, F.A., Noach, E.L. , The influence of diphenylhydantoin on intestinal glucose absorption in the rat, Eur J Pharmacol, vol. 28, no. 2, pp. 310-315. DOI
1973
Mattie, H., Goslings, W.R., Noach, E.L. , Cloxacillin and nafcillin: serum binding and its relationship to antibacterial effect in mice, J Infect Dis, vol. 128, no. 2, pp. 170-177. DOI
Noach, E.L., Van Rees, H., De Wolff, F.A. , Effects of diphenylhydantoin (DPH) on absorptive processes in the rat jejunum, Arch Int Pharmacodyn Ther, vol. 206, no. 2, pp. 392-393.
Molenaar, P.C., Polak, R.L. , Newly formed acetylcholine in synaptic vesicles in brain tissue, Brain Res, vol. 62, no. 2, pp. 537-542. DOI
Gispen, W.H., van der Poel, A.M., Wimersma Greidanus, T.B. , Pituitary-adrenal influences on behavior: responses to test situation with or without electric footshock, Physiol Behav, vol. 10, no. 2, pp. 345-350. DOI
Molenaar, P.C., Nickolson, V.J., Polak, R.L. , Preferential release of newly synthesized 3 H-acetylcholine from rat cerebral cortex slices in vitro, Br J Pharmacol, vol. 47, no. 1, pp. 97-108.
Driessen, O.M., Thesingh, C.W., van den Bosch, N. , The localization of 125iodide, 3H-inulin and 3H-acetylcholine in autoradiographic model experiments, Histochemistry and Cell Biology, vol. 36, no. 2, pp. 115-121. DOI
Van Rees, H., Noach, E.L. , The intestinal absorption of dyphenylhydantoin from a suspension in rats, Arch Int Pharmacodyn Ther, vol. 206, no. 1, pp. 76-83.
1972
Gispen, W.H., Schotman, P., de Kloet, E.R. , Brain RNA and hypophysectomy; a topographical study, Neuroendocrinology, vol. 9, no. 5, pp. 285-96. DOI
van der Poel, A.M. , Centrally acting cholinolytics and the choice behaviour of the rat, Prog Brain Res, vol. 36, pp. 127-138. DOI
van Rees, G.P. , Control of ovulation by the anterior pituitary gland, Prog Brain Res, vol. 38, pp. 193-210. DOI
1971
Bonta, I.L., De Vos, C.J., Grijsen, H., Hillen, F.C., Noach, E.L., Sim, A.W. , 1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA-like compound, with potential use in extrapyramidal diseases, Br J Pharmacol, vol. 43, no. 3, pp. 514-535.
Hillen, F.C., Noach, E.L. , 1-hydroxy-3-amino-pyrrolidone-2 (HA-966): effects on dopamine metabolism in the rat corpus striatum, Arch Int Pharmacodyn Ther, vol. 189, no. 2, pp. 401-402.
De Wolff, F.A., Suijkerbuijk-Van, B., Van Rees, H., Noach, E.L. , ATPase activity in rat jejunal epithelial cell homogenate: its relation to intestinal sodium chloride absorption and its change under the influence of some drugs, Arch Int Pharmacodyn Ther, vol. 189, no. 2, pp. 399-400.
de Bruijne, A.W., Van Rees, H., van Steveninck, J. , Influence of dimethylsulfoxide on transmembrane transport, Biochem Pharmacol, vol. 20, no. 10, pp. 2687-2693. DOI
Noach, E.L., Hillen, F.C., De Groot, C.A. , Interaction of alpha-methyldopa and guanethidine on the blood pressure of the pithed rat, Arch Int Pharmacodyn Ther, vol. 189, no. 2, pp. 403-404.
Molenaar, P.C., Nickolson, V.J., Polak, R.L. , Preferential release of newly synthesized acetylcholine from rat cerebral cortex in vitro, J Physiol, vol. 213, no. Suppl, pp. 64P-65P.
Bouquet, J., Noach, E.L. , Some aspects of the adrenergic system of the isolated rat seminal vesicle, Arch Int Pharmacodyn Ther, vol. 189, no. 2, pp. 397-398.
Cohen, E.M., Christen, P.J., Mobach, E. , The inactivation by oximes of sarin and soman in plasma from various species. I. The influence of diacetylmonoxime on the hydrolysis of sarin, Proc KNAW Series C-Biological and Medical Sciences, vol. 74, no. 2, pp. 113-131.
De Wolff, F.A., Hillen, F.C., Sprangers, W.J., Suijkerbuijk-Van, B., Noach, E.L. , The influence of folic acid on the action of diphenylhydantoin, Arch Int Pharmacodyn Ther, vol. 194, no. 2, pp. 316-317.
Hillen, F.C., Noach, E.L. , The influence of 1-hydroxy-3-amino pyrrolidinone-2 (HA-966) on dopamine metabolism in the corpus striatum, Eur J Pharmacol, vol. 16, no. 2, pp. 222-224. DOI
Kaasjager, W.A., Woodbury, D.M., van Dieten, J.A.M.J., van Rees, G.P. , The role played by the preoptic region and the hypothalamus in spontaneous ovulation and ovulation induced by progesterone, Neuroendocrinology, vol. 7, no. 1, pp. 54-64. DOI
van der Poel, A.M., Remmelts, M. , The effects of anticholinergics on the behavior of the rat in a solitary and in a social situation, Arch Int Pharmacodyn Ther, vol. 189, no. 2, pp. 394-396.
1970
Fortier, C., Delgado, A., Ducommun, P., Ducommun, S., Dupont, A., Jobin, M., Kraicer, J., Intosh-Hardt, B., Marceau, H., Mialhe, P., Mialhe-Voloss, C., Rerup, C., van Rees, G.P. , Functional interrelationships between the adenohypophysis, thyroid, adrenal cortex and gonads, Can Med Assoc J, vol. 103, no. 8, pp. 864-874.
Molenaar, P.C., Polak, R.L. , Stimulation by atropine of acetylcholine release and synthesis in cortical slices from rat brain, Br J Pharmacol, vol. 40, no. 3, pp. 406-417.
Polak, R.L., Cohen, E.M. , The influence of oximes on the distribution of 32P in the body of the rat after injection of 32P-sarin, Biochem Pharmacol, vol. 19, no. 3, pp. 865-876. DOI
Polak, R.L., Cohen, E.M. , The binding of sarin in the blood plasma of the rat, Biochem Pharmacol, vol. 19, no. 3, pp. 877-881. DOI
1969
Bonta, I.L., De Vos, C.J., Hillen, F.C. , 1-hydroxy-3-amino-pyrrolidone-2 (HA-966). I. Behaviour and motor effects, Arch Int Pharmacodyn Ther, vol. 182, no. 2, pp. 391-393.
Hillen, F.C., Sim, A.W., Vincent, E., Noach, E.L., Bonta, I.L. , 1-hydroxy-3-amino-pyrrolidone-2 (HA-966). 3. Neurochemical aspects, Arch Int Pharmacodyn Ther, vol. 182, no. 2, pp. 396-397.
Cohen, E.M. , Cell structures and their functions, Pharm Weekbl, vol. 104, no. 48, pp. 1485-1503.
De Groot, C.A. , Effect of insulin and blood-sugar changes on ascorbic acid values in ovaries and other tissues, J Endocrinol, vol. 43, no. 4, Suppl, pp. i–xliv. DOI
Driessen, O.M., Noach, E.L. , Effect of testosterone propionate on the distribution of radioactive iodide in recently thyroidectomized rats, Acta Endocrinologica, vol. 60, no. 2, pp. 303-314. DOI
Bouquet, J., Kroon, M.C., Van Rees, H., Stakenburg, J., De Wolff, F.A., Noach, E.L. , Influence of guanethidine on contractions of isolated seminal vesicles of the rat, Arch Int Pharmacodyn Ther, vol. 182, no. 2, pp. 402.
van Rees, G.P. , Induction of ovulation in pseudopregnant rats, J Endocrinol, vol. 43, no. 4, Suppl, pp. i-xliv. DOI
van Rees, G.P. , Regulation of LH secretion in the rat, Acta Physiol Pharmacol Neerl, vol. 15, no. 2, pp. 136-140.
Noach, E.L., Hillen, F.C. , The effect of prenylamine (Segontin) on sympathetic nerve fibers and receptors, Pharm Weekbl, vol. 104, no. 26, pp. 679-686.
1968
Chin A Paw, E.N., Knegt-Verpalen, J.W.M., Noach, E.L. , Absence of modification of tyramine pressor effects by octopamine in reserpinized rats, Eur J Pharmacol, vol. 3, no. 1, pp. 78-80. DOI
Driessen, O.M., Noach, E.L. , Effect of testosterone propionate on the renal excretion of iodide-131 in the rat, Eur J Pharmacol, vol. 3, no. 3, pp. 257-262. DOI